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FAST REVISION
General Medicine
🟡 Jaundice & Liver Disorders
| Condition | Key Features |
|---|---|
| Unconjugated hyperbilirubinemia | No urine bilirubin; seen in hemolysis |
| Conjugated hyperbilirubinemia | Present in Dubin – Johnson syndrome |
| Crigler – Najjar Type II | Autosomal recessive |
| BSP test | Diagnoses Dubin – Johnson |
| ↑ 5’-Nucleotidase | Cholestasis marker |
| ↓ Alk Phosphatase | Seen in hypothyroidism |
🦠 Viral Hepatitis
- Hepatitis E: Feco-oral; dangerous in pregnancy
- Councilman bodies: Acute viral hepatitis
- Most chronic virus: Hepatitis C
- HBV infectivity: HBsAg + HBeAg
- Window period: ↓ HBsAg, ↑ anti-HBs
- Perinatal HBV transmission: 90% risk
- First marker in acute HBV: HBsAg
- HBV P gene: Codes reverse transcriptase
- Hepatitis A prophylaxis: Human Ig
- Most epidemic-prone hepatitis in India: Hepatitis E