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General Medicine
For a diagnosis of systemic lupus erythematosus (SLE), at least four out of the eleven listed disorders must be present. These include malar rash, discoid rash, photosensitivity, oral ulcers, arthritis, serositis, renal disorder, neurologic disord
General Pathology
Paroxysmal nocturnal hemoglobinuria is due to an acquired red cell defect, specifically a defect in the cell membrane that makes red blood cells susceptible to lysis.