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General Medicine
Alcohol induces lipid peroxidation primarily by generating reactive oxygen species during its metabolism by the cytochrome P450 system in the liver. These free radicals can damage cell membranes and organelles.
General Medicine
Peutz-Jeghers syndrome is associated with mutations in the LKB1/STK11 gene. This autosomal dominant disorder is characterized by gastrointestinal hamartomatous polyps and mucocutaneous hyperpigmentation, and it increases the risk of various malign