FAST REVISION
Pharmacology
Dimercaprol (British antilewisite; BAL)
1. Poisoning by As, Hg, Au, Bi, Ni, Sb: it is administered i.m., 5 mg/kg stat, followed by 2-3 mg/kg every 4 – 8 hours for 2 days, then once or twice a day for 10 days. It is partly ox
Physiology
Sympathetic activity enhances sodium and water reabsorption in the PCT (proximal convoluted tubule) through increased activity of sodium pumps and sodium-potassium-2-chloride cotransporters, which helps in fluid and electrolyte retention.
General Pathology
Severe abdominal pain, diarrhea, and hypercalcemia are typical clinical presentations of a gastrinoma.