NEET MDS Shorts
842591
PharmacologyCephalosporins with antipseudomonal action:
Cefoperazone Ceftazidime
279493
PharmacologyTreatment of meningococcal meningitis:
Drug of choice – Penicillin G
In case of penicillin resistance, third generation cephalosporins should be used ( Ceftriaxone / CefotaximeIn case of penicillin / cephalosporin allergy, Chloramphenicol is used
967785
PharmacologyPhase III studies are randomized controlled multicenter trials on large patient groups (300–3,000 or more depending upon the disease/medical condition studied) and are aimed at being the definitive assessment of how effective the drug is, in comparison with current 'gold standard' treatment.
423922
PharmacologyAlkalinization of urine is used in patients receiving high dose methotrexate to promote renal excretion and to avoid nephrotoxicity
IV Sodium bicarbonate is used to maintain urine pH above 7.0 to avoid precipitation of methotrexate (a weak acid) in the acid pH of renal tubules
230619
Pharmacology
cephalosporin are bactericidal, are potentially cross allergenic with penicillin, resistant to penicillinase
536387
PharmacologyHeparin-associated thrombocytopenia may be associated with irreversible aggregation of platelets and treating venous thromboembolism. The incidence of thrombocytopenia after administration of LMWH is lower than with standard heparin. Adverse drug reactions like those caused by standard heparin have been seen during therapy with LMWH, and overdose is treated with protamine.
337875
PharmacologyA number of medications may elicit headache as a side effect.
Common offenders include nitroglycerin, hydralazine, calcium-channel blockers, digitalis, and estrogen.
Recreational drugs such as nicotine, alcohol, marijuana, and amphetamines can also induce headache.
448433
PharmacologyHeparin Heparin does not the cross the placenta.
Hence its safe for use in pregnant patients who need anticoagulation.