NEET MDS Shorts
602532
PharmacologyPassive diffusion: The movement of drug across a membrane in a manner driven solely by the concentration gradient. In passive diffusion, drug moves from a region of greater concentration to a region of lesser concentration.
480873
PharmacologyPyridoxine – drug interactions :
INH – induces a pyridoxine deficiency state
Levodopa – pyridoxine promotes peripheral conversion of levodopa to dopamine – thus it decreases therapeutic action of levodopa in the brain
Oral contraceptive pills – decrease pyridoxine levels in some females
Hydralazine – impairment of pyridoxine utilisation
4-deoxy pyridoxine – pyridoxine antagonist
848996
PharmacologyCisapride can cause QT prolongation when administered along with drugs like ketoconazole which inhibit hepatic cytochrome p-450 CYP 3A4 enzyme.
548035
PharmacologyAlbendazole is not effective against Schistosomiasis, which is caused by a parasitic worm.
270937
PharmacologyMorphine causes vomiting by stimulation of the medullary chemo receptor trigger zone
142264
PharmacologyEthohepatazine is a chemical derivative of meperidine
354540
PharmacologyThyroid inhibitors
a) Inhibit hormone synthesis (anti thyroid drugs): Propylthiouracil, Methimazole, Carbimazole
b) Inhibit iodine trapping (ionic inhibitors): Thiocyanates, Perchlorates, Nitrates.
c) Inhibit hormone release: Iodine, NaI, Kl
d) Destroy thyroid tissue: Radioactive iodine
332707
PharmacologyBeta-blockers, such as propranolol, labetalol, and pindolol, can have membrane stabilizing effects (eg, quinidinelike effects, Vaughan-Williams class I antiarrhythmic effects). This property, usually not evident with therapeutic doses, may significantly contribute to toxicity by prolonging QRS duration and impairing cardiac conduction. Seizures are more commonly observed in the drugs with quinidinelike membrane stabilizing effects.