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Pharmacology

Antibiotics in Dental Infections: When to Give What? - NEET MDS Protocol

NEET MDSINI-CET MDSINBDE

This high-yield revision note on Antibiotics in Dental Infections: When to Give What? - NEET MDS Protocol covers everything examiners typically test under Pharmacology — structured as quick-reference tables, clinical correlations, mnemonics and previous-year-style high-yield points. It's built for last-mile revision before NEET MDS, INI-CET MDS and INBDE, so you can scan it in minutes instead of re-reading a whole textbook chapter.

ConditionFirst-line AntibioticAlternative (Penicillin allergy)
Acute periapical/periodontal abscess (localized, no systemic signs)Usually NO antibiotic needed - drainage/pulp therapy is definitive treatment-
Spreading odontogenic infection with cellulitis/feverAmoxicillin 500mg TDS (± clavulanic acid if resistant)Clindamycin 300mg QDS or Azithromycin
Severe/life-threatening (Ludwig's angina, fascial space infection)IV Amoxicillin-clavulanate + Metronidazole (covers anaerobes)Clindamycin IV
Necrotizing ulcerative gingivitis (ANUG)Metronidazole (covers anaerobes/spirochetes)-
Infective endocarditis prophylaxis (high-risk cardiac patients)Amoxicillin 2g PO, 30-60 min before procedureClindamycin 600mg PO / Azithromycin 500mg
Mnemonic: "Drain FIRST, drugs SECOND" - antibiotics never substitute for source control (pulp extirpation/incision & drainage) in localized dental infection - top conceptual NEET MDS trap question.
HY: Metronidazole is added specifically for ANAEROBIC coverage (odontogenic infections are typically POLYMICROBIAL - mixed aerobic + anaerobic). Clindamycin is preferred alternative in penicillin allergy due to excellent bone penetration AND anaerobic coverage (unlike erythromycin).
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