This high-yield revision note on Local Anesthetics in Dentistry: Lignocaine to Bupivacaine - Dose Calculation covers everything examiners typically test under Pharmacology — structured as quick-reference tables, clinical correlations, mnemonics and previous-year-style high-yield points. It's built for last-mile revision before NEET MDS, INI-CET MDS and INBDE, so you can scan it in minutes instead of re-reading a whole textbook chapter.
| Drug | Class/Onset | Max Dose (mg/kg) | Notes |
|---|---|---|---|
| Lignocaine (Lidocaine) 2% | Amide, fast onset | 4.4 mg/kg (max 300mg without vasoconstrictor; 500mg with epi, absolute max 7mg/kg with epi per some texts) | Gold standard, with 1:100,000 or 1:200,000 epinephrine |
| Bupivacaine | Amide, slow onset, LONG duration (postop pain control) | 1.3-2 mg/kg (max ~90mg) | Most cardiotoxic LA - avoid in cardiac patients; used for long procedures |
| Articaine 4% | Amide (with ester link too - unique thiophene ring), extra potent | 7 mg/kg (max 500mg) | Best bone/soft tissue diffusion, controversial paresthesia risk with IAN block |
| Mepivacaine | Amide | 4.4 mg/kg (max 300mg) | Used WITHOUT vasoconstrictor in cardiac/pregnant patients (has mild intrinsic vasoconstriction) |
| Prilocaine | Amide | 6 mg/kg (max 400mg) | Risk of methemoglobinemia at high doses |
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