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Dental Public Health

Dental Caries Theories: Acidogenic to Ecological Plaque Hypothesis

NEET MDSINI-CET MDSINBDE

This high-yield revision note on Dental Caries Theories: Acidogenic to Ecological Plaque Hypothesis covers everything examiners typically test under Dental Public Health — structured as quick-reference tables, clinical correlations, mnemonics and previous-year-style high-yield points. It's built for last-mile revision before NEET MDS, INI-CET MDS and INBDE, so you can scan it in minutes instead of re-reading a whole textbook chapter.

TheoryProposed ByCore Concept
Chemico-parasitic (Acidogenic) theoryW.D. Miller (1890)Oral bacteria ferment carbohydrates producing acid → demineralization of enamel; classical, most widely accepted foundational theory
Proteolytic theoryGottliebBacteria attack the organic (protein) matrix of enamel first, before mineral loss
Proteolysis-chelation theorySchatzSimultaneous protein breakdown AND chelation of mineral by decomposition products, can occur even at neutral/alkaline pH
Keyes' triad (later tetrad)Keyes, modified by NewbrunCaries requires Host (susceptible tooth) + Microorganisms + Substrate (fermentable carbohydrate), with Time as the 4th factor
Ecological plaque hypothesisMarshCaries results from an ecological SHIFT within resident plaque flora (increase in acidogenic/aciduric species like S. mutans, lactobacilli) driven by frequent sugar exposure - not simple invasion by one new pathogen
Mnemonic: "H-M-S-T" = Host, Microorganism, Substrate, Time - the four elements that must overlap for caries to occur (Keyes/Newbrun tetrad, classic Venn diagram question).
HY: The Ecological Plaque Hypothesis (Marsh) is the CURRENTLY accepted model - caries is a disease of ecological imbalance/shift in the resident biofilm rather than infection by a single new "cariogenic" organism - a frequently updated, high-yield concept for recent exams.
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