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Dental Public Health

Fluoride: Mechanism, Systemic vs Topical, Fluorosis & Defluoridation

NEET MDSINI-CET MDSINBDE

This high-yield revision note on Fluoride: Mechanism, Systemic vs Topical, Fluorosis & Defluoridation covers everything examiners typically test under Dental Public Health — structured as quick-reference tables, clinical correlations, mnemonics and previous-year-style high-yield points. It's built for last-mile revision before NEET MDS, INI-CET MDS and INBDE, so you can scan it in minutes instead of re-reading a whole textbook chapter.

AspectDetail
Mechanism of actionIncorporation into hydroxyapatite as fluorapatite (more acid-resistant); inhibits bacterial enolase (blocks glycolysis/acid production); promotes remineralization of early carious lesions
Systemic sourcesWater fluoridation, fluoride supplements (tablets/drops), fluoridated salt/milk programs
Topical sourcesFluoridated toothpaste (1000-1500ppm), mouth rinses (0.05% NaF daily or 0.2% weekly), professionally applied gel/foam/varnish (APF, SnF2, 5% NaF varnish)
Dental fluorosisEnamel mottling from excess fluoride ingestion DURING enamel formation (typically before 8 years age); graded by Dean's Fluorosis Index
Defluoridation (community method)Nalgonda technique (alum + lime + bleaching powder) - most widely used low-cost method, notably in India
Mnemonic: "Fluoride works best TOPICALLY, on the surface it touches" - current understanding favors the topical (post-eruptive, surface remineralization/enolase inhibition) mechanism as the PRIMARY mode of caries prevention, over the older systemic (pre-eruptive incorporation) view.
HY: Current optimal fluoride level in community water per CDC guidance = 0.7 ppm (revised in 2015 from the earlier 0.7-1.2ppm range) - a frequently updated numeric fact. The Nalgonda technique is the classic community-level defluoridation method for excess-fluoride water sources.
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