NEET MDS Shorts
363815
Biochemistry
The biochemical defect in Osteogenesis Imperfecta, type II is a deficiency in lysyl hydroxylase.
477615
BiochemistryEnzymes are biological catalysts that increase the rate of chemical reactions
by lowering the activation energy required for the reaction to occur.
381348
Biochemistry
Gout is a form of arthritis caused by the accumulation of uric acid crystals,
specifically sodium urate crystals, in the joints. The body produces uric acid
as a waste product during the metabolism of purines, which are substances found
in certain foods and also synthesized by the body. High levels of uric acid can
lead to the formation of these crystals, which cause inflammation and pain in
the affected joints. Urea (Answer 1) is a waste product formed from the
metabolism of proteins and amino acids, while guanine (Answer 3) and
hypoxanthine (Answer 4) are purine bases involved in nucleotide metabolism, but
they do not directly form the crystals seen in gout.
899455
Biochemistry
odine is a characteristic component of Thyroxine
409391
BiochemistryThe enzyme phosphatidate phosphatase converts phosphatidic acid to diacylglycerol during synthesis of triacylglycerides.
The function of adipose tissue is the storage of fatty acids as triacylglycerols in times of plenty and the release of fatty acids during times of fasting or starvation.
Fatty acids taken in by adipocytes are stored by esterification to glycerol-3-phosphate. Glycerol-3-phosphate is derived almost entirely from the glycolytic intermediate dihydroxyacetone phosphate through the action of glycerol-3-phosphate dehydrogenase. Glycolytic enzymes are active in adipocytes during triglyceride synthesis, but those of glycogen degradation (low levels in adipocytes) and gluconeogenesis (ie, glucose-6-phosphatase) are not.
Glycerol kinase is not present to any great extent in adipocytes, so that glycerol freed during lipolysis is not used to reesterify the fatty acids being released.
The enzyme triacylglyceride lipase is turned on by phosphorylation by a cyclic AMP-dependent protein kinase following epinephrine stimulation.
697561
BiochemistryGlucose can be synthesised from Glyerol, Acetoacetate, Lactic acid
165169
BiochemistryVLDL is a lipoprotein particle synthesized in the liver and secreted into the bloodstream to transport endogenously synthesized triglycerides and cholesterol to peripheral tissues. The triglycerides in VLDL are derived from fatty acids synthesized in the liver, and the cholesterol is derived from both dietary sources and de novo synthesis in the liver. They are not usually linked covalently to apoproteins (Answer 1), nor do they primarily consist of phosphatidylcholine (Answer 2). While the types of lipids found in the diet (Answer 4) can influence the liver's synthesis of VLDL, the statement does not accurately describe the direct composition of VLDL.
583515
BiochemistryGlutamate-pyruvate trans-aminase is predominantly present In Liver