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NEETMDS- Microbiology short notes

NEET MDS Shorts

396694
Microbiology

Most bacterial endotoxins are composed of lipoprotein-polysaccharide complexes

177456
Microbiology

The destruction of microorganisms on living tissues, as long as there is contact between the tissues and the antimicrobial agent, denotes antisepsis (option 2). Antisepsis refers to the application of antimicrobial agents to living tissues to reduce the possibility of infection, sepsis, or putrefaction.




Sterilization:

This is the process of completely eliminating all forms of microbial
life, including bacteria, viruses, fungi, and spores, from an object or
surface. Sterilization is typically achieved through methods such as
autoclaving (steam under pressure), dry heat, chemical sterilants, or
radiation. Sterilization is used for medical instruments, laboratory
equipment, and other items that must be free of all microorganisms.



Antisepsis:

Antisepsis refers to the application of antimicrobial agents to
living tissues to reduce the risk of infection, sepsis, or putrefaction.
Antiseptics are used on skin and mucous membranes to prevent infection
during surgical procedures, wound care, and other medical interventions.
Common antiseptics include alcohol, iodine solutions, and chlorhexidine.



Sanitization:

Sanitization is the process of reducing the number of microorganisms
on surfaces or objects to a level considered safe by public health
standards. This does not necessarily eliminate all microorganisms but
reduces them to a level that minimizes the risk of infection or disease.
Sanitization is commonly used in food service, public restrooms, and
other environments where hygiene is important.



976969
Microbiology


Two important factors for initiation of caries by oral streptococci are production of glucosyl transferase and synthesis of insoluble dextran

321894
Microbiology


In concentrations usually applied for sterilization purposes, ethylene oxide is preferable to formaldehyde becuase it is more penetrating


360694
Microbiology


Diphtheria serious bacterial infection that usually affects the mucous
membranes of the nose and throat.

Diphtheria signs and symptoms usually begin 2 to 5 days after a person becomes
infected. Signs and symptoms may include:

A thick, gray membrane covering the throat and tonsils
A sore throat and hoarseness
Swollen glands (enlarged lymph nodes) in the neck
Difficulty breathing or rapid breathing
Nasal discharge
Fever and chills
Tiredness

Skin (cutaneous) diphtheria
A second type of diphtheria can affect the skin, causing pain, redness and
swelling similar to other bacterial skin infections. Ulcers covered by a gray
membrane also may be a sign of skin diphtheria.

566910
Microbiology

N-acetyl muramic is intermediate in the biosynthesis the cell wall

338765
Microbiology


The chemical nature of bacterial exotoxins is, a
lipopolysaccharide complex

156257
Microbiology

There are some enzymes that cause protein to coagulate rather than to produce simpler compund These are known as lab enzymes

1. Coagulase:

Definition: Coagulase is an enzyme produced by certain
bacteria, most notably Staphylococcus aureus. It catalyzes the
conversion of fibrinogen (a soluble plasma protein) into fibrin (an
insoluble protein), leading to the clotting of blood.
Function: The production of coagulase is a virulence
factor for Staphylococcus aureus, as it helps the bacteria evade
the host's immune system by forming a protective clot around the bacterial
cells. This clot can shield the bacteria from phagocytosis and other immune
responses.
Clinical Relevance: Coagulase is used in laboratory
tests to differentiate between pathogenic Staphylococcus aureus (coagulase-positive)
and non-pathogenic staphylococci (coagulase-negative).

2. Proteolytic Enzymes:

Definition: Proteolytic enzymes, also known as
proteases or peptidases, are enzymes that catalyze the breakdown of proteins
into smaller peptides or amino acids by cleaving the peptide bonds between
amino acids.
Function: These enzymes play crucial roles in various
biological processes, including digestion, protein turnover, cell signaling,
and immune responses. They are found in many organisms, including humans,
where they are involved in the digestion of dietary proteins in the stomach
and small intestine.
Types: Proteolytic enzymes can be classified based on
their mechanism of action (e.g., serine proteases, cysteine proteases,
aspartic proteases, and metalloproteases) and their substrate specificity.

Wenmycin is an antibiotic that is derived from the
bacterium Streptomyces wenyangensis. It belongs to the class of
compounds known as macrolide antibiotics, which are
characterized by their large lactone ring structure. Wenmycin has been studied
for its antimicrobial properties, particularly against certain types of
bacteria.

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