NEET MDS Shorts
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NEETMDS
Treacher Collins syndrome is a genetic disorder characterized by specific craniofacial deformities. A key feature of this condition is the underdevelopment (hypoplasia) or absence of the zygomatic complex, which are the cheekbones. This lack of support from the underdeveloped zygoma also causes the palpebral fissures (the opening between the eyelids) to slant downward, not upward. Other features include micrognathia (small jaw) and retrognathia (receding chin). Microstomia can occur, but poorly developed malar bones are a more consistently defining characteristic.
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ProsthodonticsSelective pressure impression technique is indicated in firm healthy mucosal covering over the ridge.
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Periodontics
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ProsthodonticsThe patient’s manipulative skills in handling complete dentures are best with overdentures.
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Dental Materials
The bond strength is influenced by the acidity; a lower pH can enhance the bond strength.
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MedicineTransesophageal echocardiography (TEE) is indeed the most sensitive method for detecting venous air embolism. However, it is a qualitative tool used to detect the presence of air bubbles and is not used to precisely measure the quantity of air.
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Pathology
Oncofoetal antigens are substances that are normally present in the
developing fetus but are found in abnormally high quantities in the tissues of
certain cancer cells. These antigens are proteins that can be used as markers
for the detection of certain types of cancers. The presence of these antigens in
cancer cells suggests that the tumor cells have partially reverted to a more
primitive, embryonic stage of development.
Explanation for each option:
1. á-Fetoprotein (AFP): This is an oncofoetal antigen. It is a glycoprotein that
is produced by the liver cells of the developing fetus. In adults, the
production of AFP is usually very low. However, in cases of certain cancers such
as hepatocellular carcinoma (primary liver cancer) and some types of testicular
cancer, the tumor cells start producing AFP in large amounts. Therefore, high
levels of AFP in the blood can be indicative of these cancers.
2. Carcinoembryonic antigen (CEA): CEA is another example of an oncofoetal
antigen. It is a glycoprotein that is present in the gastrointestinal tract,
pancreas, and sometimes in the respiratory and reproductive systems of a
developing fetus. In adults, CEA levels are typically very low. However, in
certain types of cancers, such as colorectal cancer, gastric cancer, and some
forms of lung, pancreatic, and breast cancer, the tumor cells may start
producing large amounts of CEA, which can be detected in the blood and used as a
tumor marker for these malignancies.
3. A and B: Both α-fetoprotein and carcinoembryonic antigen are examples of
oncofoetal antigens, so this option is correct.
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Physiology
Pacinian corpuscles are rapidly adapting mechanoreceptors that are highly sensitive to high-frequency vibrations and are responsible for detecting rapid changes in pressure.
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General MicrobiologyType VII bacteriophage types of diphtheria bacilli are associated with avirulent strains.
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NEETMDSAvulsion, which is the complete displacement of a tooth from its socket, has the highest rate of pulpal necrosis among the options listed due to the complete severance of the neurovascular supply to the pulp.