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NEET MDS Shorts

35532
Pharmacology

Ethosuximide is the drug of choice for treatment of absence seizures. 

Other drugs used in the management of absence seizures are valproic acid, lamotrigine and clonazepam.

94448
Pharmacology

Losartan has a uricosuric action in addition to being an angiotensin receptor blocker.

Allopurinol is a xanthine oxidase inhibitor which reduces the synthesis of uric acid.

65646
Pharmacology

Cephalosporins can cause allergic reactions in people with penicillin allergy. The overall rate of allergy to cephalosporins in people with penicillin allergy is approximately 5 to 10%, although rates may be higher for certain people. Allergic reactions to cephalosporins can be severe and even lifethreatening;
it is generally recommended that those allergic to penicillin avoid cephalosporins all together.

26360
Pharmacology

Dopamine as a first line of drug in patients with shock 

Dopamine in low doses can dilate renal vasculature therefore maintaining glomerular filtration.

Activates adenylate cyclase - cAMP – relaxation of vascular smooth muscle

69400
Pharmacology

Gingivitis is a form of periodontal disease. Periodontal disease is when inflammation and infection destroy the tissues that support the teeth, including the gingiva (gums), the periodontal ligaments, and the tooth sockets (alveolar bone Malocclusion of teeth (misaligned teeth), rough edges of fillings, and ill fitting or unclean mouth appliances (such as orthodontic appliances, dentures, bridges, and crowns) can irritate the gums and increase the risk of gingivitis.

Medications such as phenytoin and birth control pills, and ingestion of heavy metals such as lead and bismuth are also associated with gingivitis.

50247
Pharmacology

Adrenaline is contraindicated in hypertensive, hyperthyroid and angina patient.

Hypersensitivity to drug is absolute contraindication to any drug.

78441
Pharmacology

GlycosaminoglycAnswer (GAGs) are heteropolysaccharides. These molecules are long unbranched polysaccharides containing a repeating disaccharide unit. The disaccharide units contain either of two modified sugars N-acetylgalactosamine (GalNAc) or N-acetylglucosamine (GlcNAc) and a uronic acid such as glucuronate or iduronate. The specific GAGs of physiological significance are hyaluronic acid, dermatan sulfate, chondroitin sulfate, heparin, heparan sulfate, and keratan sulfate.

29964
Pharmacology

Iodine-131 half-life ≈ 8 days.

After ~6 half-lives, >98–99% of the isotope is degraded.

8⋅6 = 48  days → closest option is 46 days.

This is clinically relevant because it determines radiation safety precautions and therapeutic monitoring in patients receiving I-131.

30035
Pharmacology

In humans, isosorbide mononitrate is not subject to first pass metabolism in the liver.

This reduces the intra- and interindividual variations in plasma evels and leads to predictable and reproducible clinical effects.

13951
Pharmacology

Chlortetracycline acts by interfering with protein synthesis on bacterial but not mammalian ribosomes

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