NEET MDS Shorts
99808
Pharmacology
The penicillins all act by interfering with bacterial cell wall synthesis, by inhibiting cross-linking of the mucopeptides in the cell wall and as such are bacteriocidal. Bacteria are attacked when cells are dividing and so in theory antibiotics that are bacteriostatic would decrease the efficacy of bacteriocidal drugs. However, this doesn’t often cause a problem but tetracycline and penicillin are antagonistic and should not be used at the same time. Metronidazole is the antibiotic of choice for anaerobic infections.
22958
Pharmacology
Oprelvekin (Interleukin 11) is the only agent approved by the FDA for treatment of thrombocytopenia secondary to myelosuppressive cancer chemotherapy
Filgrastim (G-CSF) and Sargramostim (GM-SCF) are used in the treatment of neutropenia
Erythropoietin is used in treatment of anemia
11314
Pharmacology
Functions of delta type opioid receptors are: supraspinal analgesia
spinal analgesia
modulation of hormone and neurotransmitter release
30035
Pharmacology
In humans, isosorbide mononitrate is not subject to first pass metabolism in the liver.
This reduces the intra- and interindividual variations in plasma evels and leads to predictable and reproducible clinical effects.
68087
Pharmacology
Acetazolamide is a carbonic acid anhydrase stimulant Acetazolamide, non-competitively (but reversibly) inhibits carbonic anhydrase in proximal tubular cells.
86715
Pharmacology
Heparin-associated thrombocytopenia may be associated with irreversible aggregation of platelets and treating venous thromboembolism. The incidence of thrombocytopenia after administration of LMWH is lower than with standard heparin. Adverse drug reactions like those caused by standard heparin have been seen during therapy with LMWH, and overdose is treated with protamine.
61911
Pharmacology
Miconazole is an imidazole anti-fungal drug, Nystatin is a polyene anti-fungal drug and itraconazole is a triazole anti-fungal.
Aciclovir is an anti-viral drug and chlorhexidine is an antiseptic.cloxacillin is penicillin derivative.
82002
Pharmacology
Phase III studies are randomized controlled multicenter trials on large patient groups (300–3,000 or more depending upon the disease/medical condition studied) and are aimed at being the definitive assessment of how effective the drug is, in comparison with current 'gold standard' treatment.
22269
Pharmacology
Treatment with a single 200-mg dose of doxycycline has been recommended As studies in volunteers demonstrated conclusively, the disease is an immunizing process. Patients who have recovered from cholera are solidly immune for at least 3 years
98141
Pharmacology
Tyrosine kinase inhibitors are used in the treatment of: Chronic myeloid leukemia
Acute lymphoblastic leukemia ( philadelphia chromosome positive cases )
Head and neck malignancies
Non small cell carcinoma lung
Gastrointestinal stromal tumours
Hepatocellular cancer
Renal cell carcinoma
Pancreatic cancer
Colorectal cancer