NEET MDS Shorts
76620
General Medicine
Protein S, in complex with activated protein C, acts as a cofactor for the inhibition of factor Xa, thus playing a role in the regulation of the coagulation cascade and preventing thrombus formation.
28802
General Medicine
Hemophilia A is a congenital defect due to various abnormalities of the gene on the X chromosome that codes for factor VIII, leading to a hemorrhagic diathesis. Hageman trait is also congenital but does not directly cause a bleeding disorder.
16904
General Medicine
Hydrocortisone, a glucocorticoid, is administered to reduce vascular permeability and suppress the systemic inflammatory response in anaphylaxis. Its effects are not immediate but can help in preventing a biphasic reaction and prolonging symptoms.
89816
General MedicineThe most likely precursor to bronchiectasis is bronchopneumonia
64342
General Medicine
Gastrinomas in Zollinger Ellison syndrome are most commonly found in the pancreas, particularly in the head of the pancreas. The term "gastrinoma triangle" refers to the area between the duodenum and pancreas where these tumors are frequently located.
79450
General Medicine
Digoxin is a positive inotrope, hence it increases the force of myocardial contraction and may be effective in heart failure. It is a cardiac glycoside, which reduces the conductivity of the atrioventricular (AV) node and which may be used in atrial fibrillation.
Digoxin has a long half-life and is given once daily. It is cleared by the renal system and hence renal impairment requires the reduction of digoxin dose.
Arrhythmias, such as atrial tachycardia, may be a sign of digoxin toxicity.
Digoxin toxicity is enhanced if there are 67 electrolyte disturbances, especially hypokalaemia, hypomagnesaemia and hypercalcaemia.
18200
General MedicineMyocardial infarction most often results in mitral regurgitation. MI can damage papillary muscles or cause left ventricular dysfunction, leading to mitral valve incompetence. This is the most common valvular complication following MI, especially inferior wall infarcts.
25004
General MedicineSerum glutamic oxaloacetic transaminase (SGOT/AST) is increased in myocardial infarction. AST is released from damaged myocardial cells and peaks 24-48 hours after MI. While not specific to heart, it was historically used for MI diagnosis before troponins became available.
33111
General Medicine
Alcoholic cirrhosis is characterized by the presence of extensive scar tissue (fibrosis) and regenerative nodules within the liver. This results from chronic alcohol-induced damage to hepatocytes and the subsequent wound healing response.
93240
General MedicineCongenital rubella syndrome can lead to various complications, including patent ductus arteriosus, sensory nerve deafness, and spontaneous abortion. However, the statement "None of the above" is incorrect as all listed conditions can occur due to the syndrome.