📖 Oral Pathology
Syndromes & Characteristic Clinical Signs
Oral Pathology-
Bull Neck: Seen in Diphtheria and Ludwig's Angina.
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Bull's Eye Lesion / Target Lesions: Characteristic of Stevens-Johnson Syndrome and Erythema Multiforme.
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Bull's Teeth: Refers to Taurodontism.
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Circus Rubber Man: Clinical appearance associated with Ehlers-Danlos Syndrome (due to hypermobility and skin elasticity).
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Claw Hands: A physical deformity seen in advanced Scleroderma.
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Coup de Sabre: A linear depression or groove resembling a "saber cut" seen in Facial Hemiatrophy (Parry-Romberg Syndrome) and localized Scleroderma (linear scleroderma).
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CREST Syndrome: A limited form of Scleroderma, characterized by:
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Calcinosis
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Raynaud's phenomenon
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Esophageal dysfunction
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Sclerodactyly
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Telangiectasias
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Crowe's Sign: Axillary or inguinal freckling seen in Neurofibromatosis Type 1.
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Frog Facies: A characteristic facial appearance seen in Crouzon Syndrome (due to midfacial hypoplasia and exophthalmos).
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Gorlin Sign: The ability to touch the tip of the nose with the tongue, seen in Ehlers-Danlos Syndrome (due to increased joint laxity).
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Hockey Stick Deformity of Femur and Shepherd's Crook Sign: Radiographic findings typically associated with Fibrous Dysplasia.
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Parrot's Beak Nose: A nasal deformity seen in Crouzon Syndrome.
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Red Strawberry Tongue and Pastia's Lines: Clinical signs characteristic of Scarlet Fever.
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Rodent Facies: A facial appearance often associated with Thalassemia.
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Simian Stance: A stooped posture, reminiscent of an ape, seen in Paget's Disease of Bone.
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Snail Track Ulcers: Serpiginous, grayish-white lesions on mucous membranes, characteristic of Syphilis (mucous patches in secondary syphilis).
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Socks Feet and Mitten Hands: Refers to syndactyly (fusion of digits) appearing like a sock or mitten, seen in Apert's Syndrome.
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Parrot Beak Shaped Nails: A nail deformity (onychogryphosis) seen in Congenital Syphilis.
Chemotherapy & Radiation Effects
Oral Pathology-
Chemotherapy Acute Changes: The two common acute changes are hemorrhage and mucositis.
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Radiosensitivity of Glands: Serous type of glands exhibit more radiosensitivity compared to mucous and mixed glands.
Specific Histopathological & Clinical Features
Oral Pathology-
Calcifying Odontogenic Cyst (COC) / Gorlin Cyst: Characterized by Ghost Cells.
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Aneurysmal Bone Cyst (ABC): Associated with a "blood-soaked" appearance on gross examination.
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Radicular Cyst - Common Site: Maxillary anterior teeth (due to higher incidence of trauma).
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Odontogenic Keratocyst (OKC) / Keratocystic Odontogenic Tumor (KCOT):
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Most common site: Posterior mandible (similar to ameloblastoma).
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Expansion: Tends to expand antero-posteriorly; buccal and lingual expansion seen in late stages.
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Basal layer histology: Tall columnar cells with palisaded nuclei – "row of tombstones" or "picket fence appearance."
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Classification: Now considered a benign odontogenic neoplasm (KCOT) in recent WHO classifications.
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HIGH-YIELD FACTS
Oral Pathology📝 QUICK MEMORY AIDS
- "Paget's Patients Prefer Tight Dentures" - Paget's disease causes denture tightening
- "Fibrous Faces Feel Funny" - Fibrous dysplasia features (leontiasis, Chinese script, ground glass, hockey stick)
- "Giant Cells Have Three Homes" - Hyperparathyroidism, Cherubism, Central Giant Cell Granuloma
⚡ HIGH-YIELD FACTS
- Chalk-stick fractures: Paget's disease & Osteopetrosis
- Leontiasis ossea: Paget's, Fibrous dysplasia, Cemento-ossifying fibroma
- Chinese script pattern: Fibrous dysplasia & COF
- Ground glass appearance: Fibrous dysplasia & Hyperparathyroidism
- Giant cells + vascular stroma + hemosiderin: Hyperparathyroidism, Cherubism, CGCG
- Triads to remember: Hutchinson's, Melkersson-Rosenthal, Ascher syndrome
