MDS PREP
Radiation injury to the haemopoietic system of the bone marrow occurs when the whole body exposure ranges between
1. 50-100 rads
2. 200-1000 rads
3. 1000-5000 rads
4. 10,000 rads to more
Radiation injury to the hematopoietic system occurs when whole body exposure ranges between 200-1000 rads.
Which of the following has been implicated due to sunlight
1. Basal cell carcinoma
2. Lymphoepithelioma
3. Junctional nevus
4. Verruca vulgaris
Oral Pathology
Answer: 1
Basal cell carcinoma (BCC) is a type of skin cancer that is strongly associated with prolonged exposure to ultraviolet (UV) radiation from sunlight.
Which of the following is the MOST likely explanation for when two days after removal of a cancerous neck lesion, there is thigh and calf cramps, tingling around the lips, low serum calcium, and high serum phosphate?
1) Hyperparathyroidism
2) Primary hypoparathyroidism
3) Pseudohypoparathyroidism
4) Renal failure
General Pathology Answer: 2
The symptoms described, including low serum calcium and high serum phosphate, are indicative of primary hypoparathyroidism, which can occur after the removal of parathyroid glands.
Giant cells are a characteristic histopathologic finding in
1. Aphthous ulcers
2. Aneurysmal bone cyst
3. Brown tumour of hyper parathyroidism
4. Dentigerous cyst
Oral Pathology
Answer: 2
Giant cells are a characteristic histopathologic finding in an aneurysmal bone cyst.
Bite cells are seen in -
1) G6PD deficiency
2) SCA
3) Hereditary spherocytosis
4) Trauma
General Pathology
Answer: 1
Bite cells are characteristic of G6PD deficiency, resulting from oxidative damage to red blood cells.
Patient giving history of thrombocytopenic purpura reports for extraction. What could be the most common postoperative complication?
1. Oedema
2. Haemorrhage
3. Infection spreading through tissue spaces
4. Dry socket
Oral Pathology
Answer: 2
The most common postoperative complication in thrombocytopenic purpura is hemorrhage.
In a patient with MEN I, which of the following is NOT commonly found?
1) Gastrinomas
2) Insulinomas
3) Parathyroid adenomas
4) Oral and intestinal ganglioneuromatosis
Oral and intestinal ganglioneuromatosis is not commonly found in MEN I; it is associated with MEN II.
Examples of oncofoetal antigen is/are:
1. á -fetoprotein
2. Carcinoembryonic antigen
3. A and B
4. None of the above
Pathology Answer: 3
Oncofoetal antigens are substances that are normally present in the
developing fetus but are found in abnormally high quantities in the tissues of
certain cancer cells. These antigens are proteins that can be used as markers
for the detection of certain types of cancers. The presence of these antigens in
cancer cells suggests that the tumor cells have partially reverted to a more
primitive, embryonic stage of development.
Explanation for each option:
1. á-Fetoprotein (AFP): This is an oncofoetal antigen. It is a glycoprotein that
is produced by the liver cells of the developing fetus. In adults, the
production of AFP is usually very low. However, in cases of certain cancers such
as hepatocellular carcinoma (primary liver cancer) and some types of testicular
cancer, the tumor cells start producing AFP in large amounts. Therefore, high
levels of AFP in the blood can be indicative of these cancers.
2. Carcinoembryonic antigen (CEA): CEA is another example of an oncofoetal
antigen. It is a glycoprotein that is present in the gastrointestinal tract,
pancreas, and sometimes in the respiratory and reproductive systems of a
developing fetus. In adults, CEA levels are typically very low. However, in
certain types of cancers, such as colorectal cancer, gastric cancer, and some
forms of lung, pancreatic, and breast cancer, the tumor cells may start
producing large amounts of CEA, which can be detected in the blood and used as a
tumor marker for these malignancies.
3. A and B: Both α-fetoprotein and carcinoembryonic antigen are examples of
oncofoetal antigens, so this option is correct.