MDS PREP
Biochemical abnormality associated with osteogenesis imperfecta is increase in
1. Alkaline phosphatase
2. Acid phosphatase
3. Bicarbonate ion
4. Phosphorylase enzyme
The biochemical abnormality associated with osteogenesis imperfecta is an increase in acid phosphatase.
Precancerous potential in Plummer-Vinson syndrome may be due to change in the epithelium like
1. Atrophy
2. Hypertrophy
3. Acanthosia
4. All the above
Oral Pathology
Answer: 1
Plummer-Vinson syndrome is associated with atrophic changes in the
epithelium, which can lead to an increased risk of cancer
Plummer-Vinson syndrome is characterized by a classic triad of
clinical features: dysphagia (difficulty swallowing), iron-deficiency anemia,
and esophageal webs. Additional symptoms may include glossitis (inflammation of
the tongue), koilonychia (spoon-shaped nails), and cheilitis (inflammation of
the lips).
Clinical Features of Plummer-Vinson Syndrome:
Dysphagia:
Difficulty swallowing due to the presence of esophageal webs, which
can obstruct the esophagus.
Iron-Deficiency Anemia:
Resulting from chronic blood loss or malabsorption, leading to
fatigue and weakness.
Esophageal Webs:
Thin membranes that form in the esophagus, contributing to
swallowing difficulties.
Glossitis:
Inflammation of the tongue, which may appear smooth and swollen.
Koilonychia:
Spoon-shaped nails that can indicate iron deficiency.
Cheilitis:
Inflammation and cracking of the lips, often associated with
nutritional deficiencies.
Fatigue and Weakness:
Common symptoms due to anemia and nutritional deficiencies.
Associated Risks:
Esophageal Cancer:
There is an increased risk of developing esophageal cancer in
individuals with Plummer-Vinson syndrome.
Prevention:
Iron Intake:
Ensuring adequate dietary iron may help prevent the onset of this
syndrome. Diagnosis and Management:
Diagnosis:
Diagnosis is typically made through clinical evaluation, endoscopy,
and imaging studies to identify esophageal webs and assess for anemia.
Management:
Treatment often involves iron supplementation to address anemia and
dietary modifications to improve iron intake. In some cases, dilation of
esophageal webs may be necessary to alleviate dysphagia
The commonest opportunistic infection in AIDS cases in India
1) Pneumocystic carinii
2) Cryptococcal meningitis
3) Toxoplasmosis
4) Tuberculosis
Oral Pathology
Answer: 1
Explanation: A compound odontoma is a type of odontogenic tumor that consists of multiple small tooth-like structures (denticles) and resembles the anatomy of normal teeth. In contrast, a complex odontoma has a more disorganized structure and does not resemble normal teeth.
False about cherubism
1. Unilocular lesion
2. Bilateral
3. Presence of giant cell
4. Delayed eruption of permanent teeth
Cherubism is not characterized by unilocular lesions; it is typically bilateral.
Basic stain used to demonstrate Reilly"s bodies
1. Alcian red
2. Blue
3. Congo red
4. Thioflavin T
Oral Pathology
Answer: 2
The basic stain used to demonstrate Reilly's bodies is blue.
Metastatic disease to the oral region is most likely to occur in which of the following locations?
1) Tongue
2) Posterior maxilla
3) Posterior mandible
4) Floor of the mouth
Oral Pathology
Answer: 3
Metastatic disease in the oral cavity typically occurs in the posterior mandible. This is because the bone in this area is relatively porous and has a rich blood supply, making it more susceptible to the spread of cancer cells from distant sites in the body.
Facial paralysis resulting in drooping of a corner of the mouth and excess lacrimation is characteristic of which of the following conditions
1. Bell"s palsy
2. Tic douloureux
3. Meniere"s disease
4. Stevens-Johnson syndrome
Oral Pathology
Answer: 1
Facial paralysis with drooping of the mouth and excess lacrimation is characteristic of Bell's palsy.
Unusual extensibility of the tongue is a characteristic feature of
1. Epidermolysis bullosa
2. Syphilis
3. Darier-White disease
4. Ehlers-Danlos syndrome
Oral Pathology
Answer: 4
Unusual extensibility of the tongue is a characteristic feature of Ehlers-Danlos syndrome.