MDS PREP
Which of the following fluoroquinolones does not require dose adjustment in a patient with creatinine clearance of < 50mg/min?
1) Ciprofloxacin
2) Trovafloxacin
3) Lomefloxacin
4) Sparfloxacin
Pharmacology Answer: 2
Fluoroquinolones that are excreted mainly by non renal mechanisms:
Pefloxacin Trovafloxacin Grepofloxacin Nalidixic acid
Which of the following antiviral drugs cannot be given orally?
1) Zidovudine
2) Zalcitabine
3) Acyclovir
4) Iodoxuridine
Pharmacology Answer: 4
Idoxuridine acts as an antiviral agent against DNA viruses by inhibiting thymidilate phosphorylase and viral DNA polymerases.
The effect of Idoxuridine results in the inability of the virus to reproduce or to infect/destroy tissue.
This product is available in the following dosage forms:Solution and Ointment
The penicillin with the best gram negative spectrum is
1. methicillin
2. phenethicillin
3. ampicillin
4. penicillin V
Pharmacology
Answer: 3
The penicillin with the best gram negative spectrum is ampicillin
Drug class causing free water clearance:
a) Diuretic
b) Saluretic
c) Uricosuric
d) Aquaretic
Pharmacology Answer: 4
Vasopressin antagonists like tolvaptan are aquaretics
Following drug interact with cefotaxime?
1) Digoxin
2) Paracetamol
3) Loop diuretics
4) Nifedipine
Pharmacology Answer: 3
Nephrotoxicity of cephalosporins is accentuated by concurrent administration of loop diuretics.
The administration of penicillin G along with probenacid results in
1. increased excretion of probenacid in the feces and perspiration
2. increased excretion of probenacid in urine
3. increased metabolism of penicillin G
4. decreased renal excretion of penicillin G
Pharmacology Answer: 4
The administration of penicillin G along with probenacid results in decreased renal excretion of penicillin G
All are symptoms of opiate with drawls except
1.diarrhea.
2. lacrimation
3.mydriasis
4.excessive speach
Carbamazepine is used in all the following conditions except?
1) Mania
2) Schizophrenia
3) Alcohol withdrawal
4) Temporal lobe epilepsy
Pharmacology Answer: 2