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NEETMDS- Pathology mcq
MDS PREP
Patient giving history of thrombocytopenic purpura reports for extraction. What could be the most common postoperative complication? 
 1. Oedema
 2. Haemorrhage
 3. Infection spreading through tissue spaces
 4. Dry socket
Oral Pathology Answer: 2

The most common postoperative complication in thrombocytopenic purpura is hemorrhage.

Which of the following is the MOST likely explanation for when two days after removal of a cancerous neck lesion, there is thigh and calf cramps, tingling around the lips, low serum calcium, and high serum phosphate?
1) Hyperparathyroidism
2) Primary hypoparathyroidism
3) Pseudohypoparathyroidism
4) Renal failure

General Pathology Answer: 2

The symptoms described are indicative of primary hypoparathyroidism, which can occur after surgical removal of the parathyroid glands.

Which of the following is a common complication of chronic fundal (type 1) gastritis?
1) Pernicious anemia
2) Gastric ulcers
3) Gastric adenocarcinoma
4) Thyrotoxicosis

General Pathology Answer: 1

Pernicious anemia is a common complication of chronic fundal (type 1) gastritis due to the loss of intrinsic factor.

The peripheral blood smear of a patient shows features of thalassemia, also presented with anemia. Family history is also +ve. The investigation was done to establish the diagnosis is -
1) ESR estimation
2) Blood spherocyte estimation
3) Bone marrow aspiration
4) Hb-electrophoresis
General Pathology Answer: 4

Hb-electrophoresis is the investigation done to establish the diagnosis of thalassemia, as it separates different hemoglobin types based on their charge.

Which of the following is NOT a typical symptom of rheumatoid arthritis?
1) Stiffness, especially in the morning
2) Asymmetric arthritis
3) Dactylitis
4) Rheumatoid nodules

General Pathology Answer: 2

Asymmetric arthritis is not a typical symptom of rheumatoid arthritis; it usually presents as symmetric polyarthritis.

The pigment associated with haemochromtosis is 
 1. Bilirubin
 2. Haemosiderin
 3. Methaemoglobin
 4. Myoglobin
Oral Pathology Answer: 2

The pigment associated with hemochromatosis is hemosiderin.

Letterer-Siwe disease is a disturbance of
1) Protein metabolism
2) Lipid metabolism
3) Mucopolysaccharide metabolism
4) Carbohydrate metabolism
Oral Pathology Answer: 2

Letterer-Siwe disease is a type of Langerhans cell histiocytosis that is associated with disturbances in lipid metabolism.

Letterer-Siwe disease is a form of Langerhans cell
histiocytosis (LCH), which is characterized by the proliferation of
Langerhans cells, a type of dendritic cell involved in immune response. This
disease primarily affects children and can present with a variety of symptoms,
including:

Bone Lesions: Osteolytic bone lesions, particularly in
the skull, vertebrae, and long bones.
Skin Rash: Erythematous lesions or seborrheic
dermatitis-like rashes.
Hematological Abnormalities: Anemia, thrombocytopenia,
and leukopenia may occur.
Organ Involvement: It can affect multiple organs,
including the liver, spleen, and lungs.

Metabolic Disturbance:

Lipid Metabolism: Letterer-Siwe disease is associated
with disturbances in lipid metabolism, particularly due to the accumulation
of lipids in the affected tissues. The Langerhans cells in this condition
can exhibit abnormal lipid storage, which is a hallmark of the disease.


Heterozygous sickle cell anemia gives protection against -
1) G6PD
2) Malaria
3) Thalassemia
4) Dengue fever
General Pathology Answer: 2

Heterozygous sickle cell anemia provides protection against malaria due to the altered red blood cell environment that is less hospitable to the malaria parasite.

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