MDS PREP
Diabetes insipidus, exophthalmous and radiolucent bone defects within the skull are most suggestive of which of the following conditions
1. Sickle cell anaemia
2. Niemann-pick disease
3. Letterer-Siwe disease
4. Hand-Schuller-Christian disease
Oral Pathology
Answer: 4
Diabetes insipidus, exophthalmos, and radiolucent bone defects suggest Hand-Schuller-Christian disease.
A 23-year-old female presented with jaundice and pallor for 2 months. Her peripheral blood smear shows the presence of spherocytes. The most relevant investigation to arrive at a diagnosis is -
1) Reticulocyte count
2) Osmotic fragility test
3) Coombs test
4) Tests for PNH
General Pathology
Answer: 3
The osmotic fragility test is the most relevant investigation for diagnosing hereditary spherocytosis, as it assesses the red blood cells' ability to withstand osmotic stress.
What is a characteristic feature of osteopetrosis?
1) Increased osteoclast activity
2) Thick and brittle bones
3) Elevated serum calcium
4) Increased bone resorption
Osteopetrosis is characterized by thick and brittle bones due to increased osteoclast activity, which is impaired, leading to abnormal bone remodeling.
Yellowith discolouration of teeth is seen in children fed on
1. High-protein diet
2. Tetracylines
3. Penicillins
4. Erythromycin
Oral Pathology
Answer: 2
Yellowish discoloration of teeth in children fed on tetracyclines is common.
Carbamazepine has been utilized to successfully diminish attacks in trigeminal neuralgia. During this therapy which of the following is indicated?
1. Clinical observation only
2. Clinical observation and complete blood and platelet counts prior to and at frequent intervals during therapy
3. No monitoring
4. None of the above
Oral Pathology
Answer: 4
During carbamazepine therapy for trigeminal neuralgia, clinical observation and blood counts are indicated.
True about Sickle cell anemia except -
1) Commonly seen in black
2) R.B.C. size is altered
3) Valine for Glutamic acid in ?-chain globin
4) Deletion of gene
General Pathology
Answer: 4
Deletion of a gene is not true about sickle cell anemia; it is caused by a point mutation, not a deletion.
Scleroderma involves
1. Tightening of oral mucosa and periodontal involvement
2. Multiple palmar keratosia
3. Raynaud"s phenomenon
4. All of the above
Oral Pathology
Answer: 4
Scleroderma involves tightening of oral mucosa, periodontal involvement, and Raynaud's phenomenon.
Which of the following is NOT associated with Reiter's syndrome?
1) Sexually transmitted infection
2) Diarrhea
3) Arthritis
4) Thyroid disorder
Thyroid disorder is not associated with Reiter's syndrome; it is linked to infections such as sexually transmitted infections and diarrhea.