MDS PREP
The peripheral blood smear of a patient shows features of thalassemia, also presented with anemia. Family history is also +ve. The investigation was done to establish the diagnosis is -
1) ESR estimation
2) Blood spherocyte estimation
3) Bone marrow aspiration
4) Hb-electrophoresis
General Pathology
Answer: 4
Hb-electrophoresis is the investigation done to establish the diagnosis of thalassemia, as it separates different hemoglobin types based on their charge.
Gingiva is most commonly affected by deficiency of
1. Vitamin A
2. Vitamin D
3. Vitamin C
4. Vitamin B
Oral Pathology
Answer: 3
Gingiva is most commonly affected by a deficiency of Vitamin C.
Using "B" film, exposure is 1 R. What is the exposure when "D" film is used
1. 1 R
2. 1/2 R
3. 1/4 R
4. 1/8 R
Oral Pathology
Answer: 3
Using "B" film, exposure of 1 R will be reduced to 1/4 R when "D" film is used.
The typical ‘crew cut’ appearance seen in sickle cell anemia because
of:
1. Capillary stasis — decreased blood supply to bone
2. Resorption of marrow leads to expansion of skull bone
3. Expansion of marrow leads to resorption of bone with apposition of new bone
on skull
4. All of the above
Pathology Answer: 3
The expansion of the marrow space due to increased hematopoiesis can lead to resorption of the outer cortical bone and the formation of new bone, resulting in the characteristic "crew cut" appearance on X-rays. This appearance is due to the trabecular pattern of the skull becoming more prominent as the outer layer is resorbed.
All are features of Intravascular hemolysis except -
1) Thrombocytopenia
2) Hemosiderinuria
3) Decreased haptoglobin
4) Raised indirect bilirubin
General Pathology
Answer: 1
Thrombocytopenia is not a feature of intravascular hemolysis; it is more commonly associated with other conditions such as bone marrow disorders.
Hypersensitively reaction seen in stomatitis venenata is
1. Type I
2. Type II
3. Type III
4. Type IV
Hypersensitivity reactions seen in stomatitis venenata are classified as Type IV.
Reticulocytosis is seen in -
1) Hemolytic anemia
2) Megaloblastic anemia
3) Aplastic anemia
4) Iron deficiency
General Pathology
Answer: 1
Reticulocytosis is commonly seen in hemolytic anemia, where there is increased production of red blood cells in response to anemia.
An undifferentiated malignant tumor on immunohistochemical stain shows cytoplasmic positivity of most of the tumor cells for cytokeratin. The most probable diagnosis of the tumor is:
1) Sarcoma
2) Lymphoma
3) Carcinoma
4) Malignant melanoma
General Pathology Answer: 3Cytokeratin positivity in an undifferentiated malignant tumor suggests that the tumor is likely a carcinoma, as cytokeratins are markers for epithelial cells.