MDS PREP
Extensive cellulitis is known as:
1. Phlegm
2. Phlegmon
3. Cellulitis majora
4. Cellulitis prima
Pathology Answer: 2
Extensive cellulitis is most accurately described by the term "phlegmon
Phlegm is a thick, viscous substance produced by the respiratory tract,
especially during a respiratory infection, which can be coughed up from the
lungs or expelled from the nose. It is primarily composed of mucus, dead cells,
and other substances.
Phlegmon is a term that is closely related to extensive cellulitis. It refers
to a severe form of cellulitis where the infection has spread deeply into the
subcutaneous tissues and is accompanied by significant inflammation, including
the presence of pus and necrosis. Phlegmon is characterized by intense pain,
swelling, redness, and warmth in the affected area. This condition often
requires aggressive medical management, including intravenous antibiotics and
surgical drainage if an abscess forms. It is an advanced and severe stage of
cellulitis that can lead to systemic infection if not treated properly.
The first vascular reaction In Inflammation is:
1. Vasoconstriction
2.
Vasodilation
3. Increased vascular permeability
4. Marginisation or pavementing
Pathology Answer: 2
The first vascular reaction in inflammation is Vasodilation.
Explanation:
Inflammation is the body's protective response to tissue injury or infection. It
is characterized by the classical signs of redness (rubor), heat (calor),
swelling (tumor), pain (dolor), and loss of function (functio laesa). The
initial vascular changes in the inflammatory process include:
1. Vasoconstriction: This is a temporary response that occurs immediately after
injury to minimize blood loss. However, it is quickly followed by the more
significant and prolonged phase of vasodilation.
2. Vasodilation: This is the first major vascular reaction in the inflammatory
response. Vasodilation occurs due to the release of substances such as
histamine, bradykinins, and prostaglandins from the damaged tissue cells and
mast cells. These substances are known as vasodilators and they cause the smooth
muscles surrounding the blood vessels to relax, leading to an increase in the
diameter of the blood vessels. This results in increased blood flow to the
injured area, which is essential for delivering white blood cells, nutrients,
and oxygen to the site of inflammation. The increased blood flow is what causes
the characteristic redness and heat of an inflamed area.
3. Increased vascular permeability: Although it is not the first vascular
reaction, increased vascular permeability is a critical component of the
inflammatory process. After vasodilation, the endothelial cells that line the
blood vessels become more permeable, allowing plasma and proteins to leak out of
the vessels into the surrounding tissue. This leads to the formation of an
exudate, which is the accumulation of fluid and proteins that makes up the
swelling (edema) seen in inflammation.
4. Marginisation or Pavementing: This is the process where neutrophils (a type
of white blood cell) move along the walls of blood vessels towards the site of
inflammation. It occurs later in the inflammatory response after the initial
vasodilation and increased vascular permeability. These cells then migrate
through the vessel walls into the tissue to combat pathogens and debris.
All are features of Intravascular hemolysis except -
1) Thrombocytopenia
2) Hemosiderinuria
3) Decreased haptoglobin
4) Raised indirect bilirubin
General Pathology
Answer: 1
Thrombocytopenia is not a feature of intravascular hemolysis; it is more commonly associated with other conditions such as bone marrow disorders.
Which of the following additional clinical findings would MOST be associated with a woman who has oral mucosal swelling, xerostomia, and intense salivary gland destructive inflammation?
1) Conjunctivitis
2) Goiter
3) Hemolytic anemia
4) Proximal muscle weakness
Conjunctivitis is often associated with Sjögren's syndrome, which can cause oral mucosal swelling and xerostomia.
The size of the red blood cells is measured by -
1) MCV
2) MCHC
3) ESR
4) MCH
General Pathology
Answer: 1
The size of red blood cells is measured by Mean Corpuscular Volume (MCV), which indicates the average volume of a red blood cell.
Osteoradionecrosis is due to
1. Endarteritis of blood vessels
2. Damage to periosteum
3. Damage to lymphatics
4. All of the above
Oral Pathology
Answer: 1
Osteoradionecrosis is due to endarteritis of blood vessels.
Oral lesions on the tongue and other mucosal surfaces of the oral cavity is commonly caused by the deficiency of
1. Vit B
2. Niacin
3. Vit C
4. Vit K
Oral Pathology
Answer: 2
Oral lesions on the tongue are commonly caused by a deficiency of Niacin (Vitamin B3).
Which of the following disease are common in ashkenazi jews
1. Hand-Schuller-Christian disease and Letterer-Siwe disease
2. Gaucher"s disease and Niemann-Pick disease
3. Amelogenesis imperfecta and dentinogenesis imperfecta
4. Achondroplasia and Marfan"s syndrome
Oral Pathology
Answer: 2
Gaucher's disease and Niemann-Pick disease are common in Ashkenazi Jews.