MDS PREP
Letterer-Siwe disease is a disturbance of
1) Protein metabolism
2) Lipid metabolism
3) Mucopolysaccharide metabolism
4) Carbohydrate metabolism
Oral Pathology
Answer: 2
Letterer-Siwe disease is a type of Langerhans cell histiocytosis that is associated with disturbances in lipid metabolism.
Letterer-Siwe disease is a form of Langerhans cell
histiocytosis (LCH), which is characterized by the proliferation of
Langerhans cells, a type of dendritic cell involved in immune response. This
disease primarily affects children and can present with a variety of symptoms,
including:
Bone Lesions: Osteolytic bone lesions, particularly in
the skull, vertebrae, and long bones.
Skin Rash: Erythematous lesions or seborrheic
dermatitis-like rashes.
Hematological Abnormalities: Anemia, thrombocytopenia,
and leukopenia may occur.
Organ Involvement: It can affect multiple organs,
including the liver, spleen, and lungs.
Metabolic Disturbance:
Lipid Metabolism: Letterer-Siwe disease is associated
with disturbances in lipid metabolism, particularly due to the accumulation
of lipids in the affected tissues. The Langerhans cells in this condition
can exhibit abnormal lipid storage, which is a hallmark of the disease.
Palatal petechiae t are present in
1. hyperthyroidism
2. infectious mononucleosis
3. osteopetrosis
4. hypophosphatasia
Oral Pathology
Answer: 2
Palatal petechiae are often seen in infectious mononucleosis, which is caused by the Epstein-Barr virus.
Microscopically, the primary cells which characterize eosinophilic granuloma are
1. Fibroblasts
2. Histiocytes
3. Plasma cells
4. Epithelial cells
Oral Pathology
Answer: 2
The primary cells that characterize eosinophilic granuloma are histiocytes.
Cafe-au-lait spots are seen in
1. Paget"s disease of bone
2. Cherubism
3. Von Recklinghausen disease
4. Von Willebrand disease
Oral Pathology
Answer: 3
Cafe-au-lait spots are seen in Von Recklinghausen disease.
If a woman 22 weeks pregnant has ankle edema and proteinuria, the presence of which of the following would determine if she has preeclampsia?
1) Diabetes mellitus
2) Hyperuricemia
3) Hypertension
4) Systemic lupus erythematosus
Hypertension is a key factor in diagnosing preeclampsia in a pregnant woman with ankle edema and proteinuria.
Abscess formation is particularly characteristic of infections with which of the following microorganisms
1) Viruses
2) Rickettsiae
3) Streptococci
4) Staphylococci
Oral Pathology
Answer: 4
Staphylococci are known for their ability to cause abscess formation due to their virulence factors.
Tetracycline stains appear as
1. Yellow and brown stains in enamel and dentin
2. Yellow and brown stains only in enamel
3. Yellow and brown stains only in dentin
4. Only yellow stain in enamel
Oral Pathology
Answer: 1
Tetracycline stains appear as yellow and brown stains in both enamel and dentin.
A bacterial disease with oral manifestations is
1) Herpes Measles
2) Measles
3) Diphtheria
4) Leishmaniasis
Oral Pathology
Answer: 3
Diphtheria serious bacterial infection that usually affects the mucous
membranes of the nose and throat.
Diphtheria signs and symptoms usually begin 2 to 5 days after a person becomes
infected. Signs and symptoms may include:
A thick, gray membrane covering the throat and tonsils
A sore throat and hoarseness
Swollen glands (enlarged lymph nodes) in the neck
Difficulty breathing or rapid breathing
Nasal discharge
Fever and chills
Tiredness
Skin (cutaneous) diphtheria
A second type of diphtheria can affect the skin, causing pain, redness and
swelling similar to other bacterial skin infections. Ulcers covered by a gray
membrane also may be a sign of skin diphtheria.