MDS PREP
True about Sickle cell anemia except -
1) Commonly seen in black
2) R.B.C. size is altered
3) Valine for Glutamic acid in ?-chain globin
4) Deletion of gene
General Pathology
Answer: 4
Deletion of a gene is not true about sickle cell anemia; it is caused by a point mutation, not a deletion.
A man of 50 years age reports with gradual loss of visual acuity and hearing power, most probably underlying cause could be
1. Fibrous dysplasia
2. Paget"s disease
3. Osteopetrosis
4. Cherubism
Oral Pathology
Answer: 2
Paget's disease is the most likely underlying cause for gradual loss of visual acuity and hearing power in a 50-year-old man.
The main purpose of intensifying screens in extraoral radiographic films is
1. To increase the contrast of film
2. To increase the exposure time
3. To decrease the speed of film
4. Decrease secondary radiation to patient
Oral Pathology
Answer: 4
The main purpose of intensifying screens is to decrease secondary radiation to the patient.
Following are the findings in sickle cell Anemia, except -
1) Fish vertebra
2) Enlarged heart
3) Splenomegaly usually seen
4) Leukocytosis
General Pathology
Answer: 3
Splenomegaly is not usually seen in sickle cell anemia; instead, autosplenectomy often occurs due to repeated splenic infarctions.
Abscess formation is particularly characteristic of infections with which of the following microorganisms
1) Viruses
2) Rickettsiae
3) Streptococci
4) Staphylococci
Oral Pathology
Answer: 4
Staphylococci are known for their ability to cause abscess formation due to their virulence factors.
A 50-year-old obese man complains of several recent abscesses in the gingival with loosening of teeth. He also suffers from itching of skin and polyuria. The most probable aetiology is
1. Scurvy
2. Myxoedema
3. Diabetes mellitus
4. Vitamin A deficiency
Oral Pathology
Answer: 3
The most probable etiology for the man’s symptoms is Diabetes mellitus, given the signs of abscesses and polyuria.
What condition is typically characterized by a malar rash, arthritis, serositis, and the presence of antinuclear antibodies?
1) Goodpasture's syndrome
2) Friedreich ataxia
3) Huntington's disease
4) Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is characterized by a malar rash, arthritis, serositis, and the presence of antinuclear antibodies.
Letterer-Siwe disease is a disturbance of
1) Protein metabolism
2) Lipid metabolism
3) Mucopolysaccharide metabolism
4) Carbohydrate metabolism
Oral Pathology
Answer: 2
Letterer-Siwe disease is a type of Langerhans cell histiocytosis that is associated with disturbances in lipid metabolism.
Letterer-Siwe disease is a form of Langerhans cell
histiocytosis (LCH), which is characterized by the proliferation of
Langerhans cells, a type of dendritic cell involved in immune response. This
disease primarily affects children and can present with a variety of symptoms,
including:
Bone Lesions: Osteolytic bone lesions, particularly in
the skull, vertebrae, and long bones.
Skin Rash: Erythematous lesions or seborrheic
dermatitis-like rashes.
Hematological Abnormalities: Anemia, thrombocytopenia,
and leukopenia may occur.
Organ Involvement: It can affect multiple organs,
including the liver, spleen, and lungs.
Metabolic Disturbance:
Lipid Metabolism: Letterer-Siwe disease is associated
with disturbances in lipid metabolism, particularly due to the accumulation
of lipids in the affected tissues. The Langerhans cells in this condition
can exhibit abnormal lipid storage, which is a hallmark of the disease.