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Benzodiazepines: Produce anterograde amnesia Act on α-subunit of GABA-A receptors Muscle relaxation with Midazolam Flumazenil: Specific antagonist Lorazepam: Difficult reversal…
Agent Key Point Cocaine First LA, sympathomimetic, antimuscarinic Lignocaine Safe in surface/infiltration, 7 mg/kg with adrenaline Bupivacaine Longest acting, no methemoglobinemia Prilocaine Causes methemoglobinemia Chloroprocaine Shortest duration EMLA Xylocaine + Prilocaine Cocaine Causes vasoconstriction…
First Local Anaesthetic: Cocaine First Muscle Relaxant: D-Tubocurarine (DTC) Intubation Pioneer: Ivan Magill (Magill's forceps) Preoperative Considerations Stop smoking ideally 8 weeks prior to surgery. Urgent warfarin reversal: Fresh Frozen Plasma (FFP). Atropine: ↓ Salivation Bronchodilation Flushing in pediatric patients…
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NEET MDS