EPITHELIUMS

Epithelial Tissue Epithelial tissue covers surfaces, usually has a basement membrane, has little extracellular material, and has no blood vessels. A basement membrane attaches the epithelial cells to underlying tissues. Most epithelia have a free surface, which is not in contact with other cells. Epithelia are classified according to the number of cell layers and the shape of the cells.

• Epitheliums contain no blood vessels.  There is normally an underlying layer of connective tissue
• Almost all epitheliums lie on a basement membrane.The basement membrane consists of  a basal lamina and  reticular lamina. The reticular lamina is connected to the basal lamina by anchoring fibrils. The reticular lamina may be absent in which case the basement membrane consist only of a basal lamina. The basal lamina consists of a   - lamina densa in the middle (physical barrier) with a lamina lucida on both sides (+charge barrier),The basement membrane is absent in ependymal cells.The basement membrane is not continuous in sinusoidal capillaries.

• Epitheliums always line or cover something
• Epithelial cells lie close together with little intercellular space
• Epithelial cells are strongly connected to one another especially those epitheliums that are subjected to mechanical forces.  

Functions of Epithelium:

→ Simple epithelium involved with diffusion, filtration, secretion, or absorption

→ Stratified epithelium protects from abrasion

→ Squamous cells function in diffusion or filtration

The Auditory Tube

• This is a funnel-shaped tube connecting the nasopharynx to the tympanic cavity.

• Its wide end is towards the nasopharynx, where it opens posterior to the inferior meatus of the nasal cavity.
• The auditory tube is 3.5 to 4 cm long; its posterior 1/3 is bony and the other 2/3 is cartilaginous.
• It bony part lies in a groove on the inferior aspect of the base of the skull, between the petrous part of the temporal bone and the greater wing of the sphenoid bone.

• The function of the auditory tube is to equalise pressure of the middle ear with atmospheric pressure.

The Middle Ear

• This part of the ear is in a narrow cavity in the petrous part of the temporal bone.
• It contains air, three auditory ossicles, a nerve and two small muscles.
• The middle ear is separated from the external acoustic meatus by the tympanic membrane.

• This cavity includes the tympanic cavity proper, the space directly internal to the tympanic membrane, and the epitympanic recess, the space superior to it.

• The middle ear is connected anteriorly with the nasopharynx by the auditory tube.
• Posterosuperiorly, the tympanic cavity connects with the mastoid cells through the aditus ad antrum (mastoid antrum).
• The tympanic cavity is lined with mucous membrane that is continuous with the mucous membrane of the auditory tube, mastoid cells, and aditus ad antrum.

Contents of the Tympanic Cavity or Middle Ear

• This cavity contains the auditory ossicles (malleus, incus and stapes); the stapedius and tensor tympani muscles; the chorda tympani nerve (a branch of the facial nerve, CN VII); and the tympanic plexus of nerves.

Veins of the Face

The Supratrochlear Vein

• This vessel begins on the forehead from a network of veins connected to the frontal tributaries of the superficial temporal vein.
• It descends near the medial plane with its fellow on the other side.
• These veins diverge near the orbits, each joining a supraorbital vein to form the facial vein near the medial canthus (angle of the eye).

The Supraorbital Vein

• This vessel begins near the zygomatic process of the temporal bone.
• It joins the tributaries of the superficial and middle temporal veins.
• It passes medially and joins the supratrochlear vein to form the facial vein near the medial canthus.

The Facial Vein

• This vein provides the major venous drainage of the face.

• It begins at the medial canthus of the eye by the union of the supraorbital and supratrochlear veins.
• It runs inferoposteriorly through the face, posterior to the facial artery, but takes a more superficial and straighter course than the artery.
• Inferior to the margin of the mandible, the facial vein is joined by the anterior branch of the retromandibular vein.
• The facial veins ends by draining into the internal jugular vein.

The Superficial Temporal Vein

• This vein drains the forehead and scalp and receives tributaries from the veins of the temple and face.
• In the region of the temporomandibular joint, this vein enters the parotid gland.

The Retromandibular Vein

• The union of the superficial temporal and maxillary veins forms this vessel, posterior to the neck of the mandible.
• It descends within the parotid gland, superficial to the external carotid artery but deep to the facial nerve.
• It divides into an anterior branch that unites with the facial vein, and a posterior branch that joins the posterior auricular vein to form the external jugular vein.

o    English: all speech sounds produced by making exhaled air audible

o    Two ways of producing sound
    at larynx
    further up in vocal tract (tongue, lips)
    
o    How to produce sound at larynx
    changes in breathing: regulate airstream from lungs to atmosphere by changing movements of vocal folds, pharynx, soft-palate, tongue, lips and jaws
    
•    inhalation: take in greater volume more quickly, abduct folds

•    expiration: variable force; use muscles of inhalation to control rate of expiration, adduct

    How to vibrate vocal cords
    
•    NOT rhythmic contraction of laryngeal muscles: would be impossible b/c frequenceies of virbration
•    Changes in air pressure cause vibrations

    o    Adduct folds increase in subglottal pressure force folds apart folds sucked back together (Bernouilli effect)
•    The vibration of vocal cords disturbs airareas of low pressure (rarefaction) alternating with areas of high pressure (compression)
•    Changes in pressure sound at ears
•    Sine waves

    o    Changes in amplitudes: loudness

    o    Changes in frequency: pitch

    o    Normal sounds have fundamental frequency, overtones or harmonics

    o    Mass of folds: critical in voice
    Low pitch of lion’s roar: due to massive fibrous pad that forms part of vocal cords
    Men: more massive vocal cords
    Larger foldsslow vibrationdeeper voice

    o    Producing vowels and constants
    Most vowels are “voiced”: vocal folds produce sounds
    Consonants: can be “voiced” (Z) or “non-voiced” (S)
•    Use higher regions of vocal tract to control by stopping, restricting airflow from vocal folds; use lips, teethaperiodic sound

o    Vocal folds and resonators emphasize and deemphasize certain frequencies
    Never hear sounds produced at vocal foldsevery sound changed by passage thru vocal tract: sinuses/resonating chambers
    Howling monkeys: large hyoid bonepowerful resonator

    o    Age-related changes in voice
    
    Infant larynx is smaller, different proportions
•    Arytenoids are proportionately larger
•    Smaller vocal apparatushigher pitch
•    Larynx sits higher easier to breathe thru nose
    Abrupt change in larynx at pubertycan’t control voice
    Older adult: normal degenerative changes in lamina propria, ossification of thyroid cartilagechanges in fundamental frequency
    Lose your voice vocal fold are irritated
•    Can’t adduct foldsair escapes

o    Singing v. speaking
    Singing: greater thoracic pressure and uneven breathing with changes in resonators

    o    Whispering
    Intercartilaginous portions of vocal folds: open to allow air to escapelesser subglottal pressureslittle vibration of foldslittle tonal quality, low volume

    o    Falsetto
    Allowing only part of vocal folds to vibrate
    Increase range by training which part of vocal folds to vibrate

    o    Colds
    Mucus secretions add mass to folds—decrease in pitch, can’t adduct folds as well

    o    Surgeryscars, fibrotic changes can interfere with voice

Sternum

o    Forms the medial part of the anterior chest wall
o    Manubrium (upper part)-clavicle and first rib articulate with the manubrium .
o    Body (middle blade)-second and tenth ribs articulate with the body via the costal cartilages
o    Xiphoid (blunt cartilaginous tip)

Ribs (12 pairs)

o    Each rib articulates with both the body and the transverse process of its corresponding
o    thoracic vertebra
o    The second to ninth ribs articulate with the body of the vertebra above'
o    Ribs curve outward, forward, and then downward
o    Anteriorly, each of the first seven ribs joins a costal cartilage that attaches to the sternum
o    Next three ribs (eighth to tenth) join the cartilage of the rib above
o    Eleventh and twelfth ribs do not attach to the sternum; are called "floating ribs"