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NEET MDS Lessons
Oral Pathology

Miescher Cheilitis

  • Definition: Granulomatous inflammation confined to the lip

Melkersson–Rosenthal Syndrome

Triad:

  1. Facial palsy
  2. Cheilitis granulomatosa
  3. Fissured tongue

Ascher Syndrome

Triad:

  1. Double lip
  2. Blepharochalasis
  3. Nontoxic thyroid enlargement

Double Lip

  • Appearance: Cupid's bow

  • Pulp Polyp (Chronic Hyperplastic Pulpitis):

    • Source of epithelium: Implantation of desquamated cells from saliva or by implantation from oral mucosa due to continuous rubbing.

    • Most common teeth: Deciduous molars and permanent first molars.

  • Periapical Granuloma: Always associated with a non-vital tooth.

  • Garre's Osteomyelitis: Another name for Chronic Osteomyelitis with Proliferative Periostitis.

  • Chemotherapy Acute Changes: The two common acute changes are hemorrhage and mucositis.

  • Radiosensitivity of Glands: Serous type of glands exhibit more radiosensitivity compared to mucous and mixed glands.

  • Bacteria adhere to acquired pellicle
  • Coaggregation enables biofilm complexity
  • Sucrose → lactic acid → pH drops → Hydroxyapatite dissolves

Key Enzymes Recap:

  • Invertase → splits sucrose
  • GTF → forms sticky glucans for adhesion
  • FTF → synthesizes fructans for biofilm scaffolding

  1. Zone 1 – Normal Dentin:
    Healthy tissue; no treatment needed

  2. Zone 2 – Subtransparent Dentin:
    Acid-demineralized, no bacteria, remineralizable; preserve

  3. Zone 3 – Transparent Dentin:
    Softened, no bacterial invasion; remineralizable; preserve

  4. Zone 4 – Turbid Dentin:
    Bacterial invasion; not remineralizable; must be removed

  5. Zone 5 – Infected Dentin:
    Fully decomposed; heavily infected; must be removed

Trotter’s Syndrome

  • Key Features: Pharyngeal pain due to nasopharyngeal carcinoma
  • Associated Structures: CN V, CN IX, CN X

 Post-Herpetic Neuralgia

  • Key Features: Persistent pain after Herpes Zoster, often affecting the ophthalmic division
  • Associated Structures: CN V1

 Ramsay Hunt Syndrome (Herpes Zoster Oticus)

  • Key Features: Facial paralysis, ear pain, vesicles, hoarseness, vertigo
  • Associated Structures: Geniculate ganglion, CN VII

 Reader’s Syndrome (Para-Trigeminal Syndrome)

  • Key Features: Trigeminal pain with ocular sympathetic paralysis
  • Associated Structures: CN V + sympathetic fibers

 Sphenopalatine Neuralgia (Sluder’s / Horton’s / Lower Half Headache)

  • Key Features: Unilateral pain in eye, maxilla, ear, mastoid, zygoma; no trigger zone; may occur at same time daily
  • Associated Structures: Vidian nerve, cavernous sinus

Horner’s Syndrome

  • Key Features: Triad of miosis, ptosis, anhidrosis; facial vasodilation
  • Associated Structures: Sympathetic chain lesion

 Frey’s Syndrome (Auriculotemporal Syndrome)

  • Key Features: Gustatory sweating during eating; flushing in temporal region
  • Associated Structures: Auriculotemporal nerve (CN V3)

 Glossopharyngeal Neuralgia

  • Key Features: Sharp pain in ear, pharynx, tonsil, posterior tongue; trigger zone in tonsillar fossa
  • Associated Structures: CN IX

Occipital Neuralgia

  • Key Features: Unilateral pain in neck and occipital region; tender spot below superior nuchal line
  • Associated Structures: Cervical plexus sensory branches

 Eagle’s Syndrome (Stylohyoid Syndrome)

  • Key Features: Deep dull pain in oropharynx, posterior auricular region, dysphagia, limited neck motion
  • Associated Structures: Elongated styloid process or calcified stylohyoid ligament

Macroglossia

  • Feature: Crenated (scalloped) lateral tongue borders

Lymphangioma of Tongue

  • Appearance: Tapioca pudding/Frog's egg

Geographic Tongue

  • Associated With: Fissured tongue
  • Histopathology: Similar to psoriasis
  • Key Feature: Munro's abscesses

Median Rhomboid Glossitis

  • Unique Sign: "Kissing lesion" on soft palate due to tongue contact

Hairy Tongue

  • Misnomer: Elongated filiform papillae—not actual hair

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