Tooth development is the complex process by which teeth form from embryonic cells, grow, and erupt into the mouth.. For human teeth to have a healthy oral environment, enamel, dentin, cementum, and the periodontium must all develop during appropriate stages of fetal development. Primary teeth start to form between the sixth and eighth weeks in utero, and permanent teeth begin to form in the twentieth week in utero.

 Overview

The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth.These cells are derived from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest.The tooth bud is organized into three parts: the enamel organ, the dental papilla and the dental follicle.

The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium.These cells give rise to ameloblasts, which produce enamel and the reduced enamel epithelium. The location where the outer enamel epithelium and inner enamel epithelium join is called the cervical loop. The growth of cervical loop cells into the deeper tissues forms Hertwig's Epithelial Root Sheath, which determines the root shape of the tooth.

The dental papilla contains cells that develop into odontoblasts, which are dentin-forming cells. Additionally, the junction between the dental papilla and inner enamel epithelium determines the crown shape of a tooth. Mesenchymal cells within the dental papilla are responsible for formation of tooth pulp.

The dental follicle gives rise to three important entities: cementoblasts, osteoblasts, and fibroblasts. Cementoblasts form the cementum of a tooth. Osteoblasts give rise to the alveolar bone around the roots of teeth. Fibroblasts develop the periodontal ligaments which connect teeth to the alveolar bone through cementum.

MANDIBULAR FIRST BICUSPID

Facial: The outline is very nearly symmetrical bilaterally, displaying a large, pointed buccal cusp. From it descends a large, well developed buccal ridge.

Lingual: This tooth has the smallest and most ill-defined lingual cusp of any of the premolars. A distinctive feature is the mesiolingual developmental groove

Proximal: The large buccal cusp tip is centered over the root tip, about at the long axis of this tooth. The very large buccal cusp and much reduced lingual cusp are very evident. You should keep in mind that the mesial marginal ridge is more cervical than the distal contact ridge; each anticipate the shape of their respective adjacent teeth.

Occlusal: The occlusal outline is diamond-shaped. The large buccal cusp dominates the occlusal surface. Marginal ridges are well developed and the mesiolingual developmental groove is consistently present. There are mesial and distal fossae with pits,

Contact Points: When viewed from the facial, each contact area/height of curvature is at about the same height.

Root Surface:-The root of the mandibular first bicuspid is usually single, but on occasion can be bifurcated (two roots).

INNERVATION OF THE DENTIN-PULP COMPLEX

1. Dentine Pulp
2. Dentin
3. Nerve Fibre Bundle
4. Nerve fibres

The nerve bundles entering the tooth pulp consist principally of sensory afferent fibers from the trigeminal nerve and sympathetic branches from the superior cervical ganglion. There are non-myelinated (C fibers) and myelinated (less than non, A-delta, A-beta) fibers. Some nerve endings terminate on or in association with the odontoblasts and others in the predentinal tubules of the crown. Few fibers are found among odontoblasts of the root.
In the cell-free zone one can find the plexus of Raschkow.

Maxillary First Deciduous Molar.

-The notation is B or I.

-It looks a bit like an upper 1st premolar.

-There are three roots.

-It has a strong bulbous enamel bulge that protrudes buccally at the mesial.

-It is the smallest of the deciduous molars in crown height and in the mesiodistal dimension.

Histology of the Periodontal Ligament (PDL)

Embryogenesis of the periodontal ligament
The PDL forms from the dental follicle shortly after root development begins
The periodontal ligament is characterized by connective tissue. The thinnest portion is at the middle third of the root. Its width decreases with age. It is a tissue with a high turnover rate.

FUNCTIONS OF PERIODONTIUM

Tooth support
Shock absorber
Sensory (vibrations appreciated in the middle ear/reflex jaw opening)

The following cells can be identified in the periodontal ligament:
a) Osteoblasts and osteoclasts b) Fibroblasts,  c) Epithelial cells
 

Rests of Malassez
d) Macrophages
e) Undifferentiated cells
f) Cementoblasts and cementoclasts (only in pathologic conditions)
The following types of fibers are found in the PDL
-Collagen fibers: groups of fibers
-Oxytalan fibers: variant of elastic fibers, perpendicular to teeth, adjacent to capillaries
-Eluanin: variant of elastic fibers
Ground substance

PERIODONTAL LIGAMENT FIBERS

Principal fibers
These fibers connect the cementum to the alveolar crest. These are:

a. Alveolar crest group: below CE junction, downward, outward
b. Horizontal group: apical to ACG, right angle
c. Oblique group: numerous, coronally to bone, oblique direction
d. Apical group: around the apex, base of socket
e. Interradicular group: multirooted teeth

Gingival ligament fibers
This group is not strictly related to periodontium. These fibers are:

a. Dentogingival: numerous, cervical cementum to f/a gingiva
b. Alveologingival: bone to f/a gingiva
c. Circular: around neck of teeth, free gingiva
d. Dentoperiosteal: cementum to alv. process or vestibule (muscle)
 e. Transseptal: cementum between adjacent teeth, over the alveolar crest
 

Blood supply of the PDL
The PDL gets its blood supply from perforating arteries (from the cribriform plate of the bundle bone). The small capillaries derive from the superior & inferior alveolar arteries. The blood supply is rich because the PDL has a very high turnover as a tissue. The posterior supply is more prominent than the anterior. The mandibular is more prominent than the maxillary.

Nerve supply
The nerve supply originates from the inferior or the superior alveolar nerves. The fibers enter from the apical region and lateral socket walls. The apical region contains more nerve endings (except Upper Incisors)

Dentogingival junction

This area contains the gingival sulcus. The normal depth of the sulcus is 0.5 to 3.0 mm (mean: 1.8 mm). Depth > 3.0 mm is considered pathologic. The sulcus contains the crevicular fluid
 

 
The dentogingival junction is surfaced by:
1) Gingival epithelium: stratified squamous keratinized epithelium 2) Sulcular epithelium: stratified squamous non-keratinized epithelium The lack of keratinization is probably due to inflammation and due to high turnover of this epithelium.
3) Junctional epithelium: flattened epithelial cells with widened intercellular spaces. In the epithelium one identifies neutrophils and monocytes.
Connective tissue
The connective tissue of the dentogingival junction contains inflammatory cells, especially polymorphonuclear neutrophils. These cells migrate to the sulcular and junctional epithelium.
The connective tissue that supports the sulcular epithelium is also structurally and functionally different than the connective tissue that supports the junctional epithelium.

Histology of the Col (=depression)

The col is found in the interdental gingiva. It is surfaced by epithelium that is identical to junctional epithelium. It is an important area because of the accumulation of bacteria, food debris and plaque that can cause periodontal disease.
Blood supply: periosteal vessels
Nerve supply: periodontal nerve fibers, infraorbital, palatine, lingual, mental, buccal

MAXILLARY LATERAL INCISORS

it is shorter, narrower, and thinner.

Facial: The maxillary lateral incisor resembles the central incisor, but is narrower mesio-distally. The mesial outline resembles the adjacent central incisor; the distal outline--and particularly the distal incisal angle is more rounded than the mesial incisal angle (which resembles that of the adjacent central incisor. The distal incisal angle resembling the mesial of the adjacent canine.

Lingual: On the lingual surface, the marginal ridges are usually prominent and terminate into a prominent cingulum. There is often a deep pit where the marginal ridges converge gingivally. A developmental groove often extends across the distal of the cingulum onto the root continuing for part or all of its length.

Proximal: In proximal view, the maxillary lateral incisor resembles the central except that the root appears longer--about 1 1/2 times longer than the crown. A line through the long axis of the tooth bisects the crown.

Incisal: In incisal view, this tooth can resemble either the central or the canine to varying degrees. The tooth is narrower mesiodistally than the upper central incisor; however, it is nearly as thick labiolingually.

Contact Points: The mesial contact is at the junction of the incisal third and the middle third. The distal contact is is located at the center of the middle third of the distal surface.

Root Surface:-The root is conical (cone-shaped) but somewhat flattened mesiodistally.