NEET MDS Lessons
Anatomy
Skeletal Muscle: 1-40 cm long fibres, 10- 60 µm thick, according to myoglobin content there are:
Red fibres: lots of myoglobin, many mitochondriam slow twitching - tire slowly
White fibres: less myoglobin, less mitochondria, fast twitching - tire quickly
Intermediate fibres:
mixture of 2 above
Most muscles have all three - in varying ratios
Structure of skeletal muscle:
Light Microscopy: Many nuclei - 35/mm, Nuclei are oval - situated peripheral, Dark and light bands
Electron Microscopy: Two types of myofilaments
Actin
- 5,6 nm
3 components:
-actin monomers,
-tropomyosin - 7 actin molecules long
- troponin
actin monomers form 2 threats that spiral
- tropomyosin - lie in the groove of the spiral
- troponin - attach every 40 nm
- one end attach to the Z line
- other end goes to the middle of the sarcomere
- Z line consists of á actinin
Myosin:
- 15 nm
- 1,6 µm long
- The molecule has a head and a tail
- tails are parallel
- heads project in a spiral
- in the middle is a thickening
- thin threats bind the myosin at thickening (M line)
Contraction:
A - band stays the same, I - band, H - bands become narrower
Myosin heads ratchet on the actin molecule
Sarcolemma: 9 nm thick, invaginate to form T-tubule,
myofibrils - attach to the sarcolemma
Sarcoplasmic Reticulum:
specialized smooth EPR, Consists of T-tubules, terminal sisternae and sarcotubules
It is speculated that there are gap junctions between the T-tubule and terminal sisterna
An impulse is carried into the fiber by the T-tubule from where it goes to the rest of the sarcoplasmic reticulum
Connective tissue coverings of the muscle
Endomycium around fibres, perimycium around bundles and epimycium around the whole muscle
Blood vessels and nerves in CT
CT goes over into tendon or aponeurosis which attaches to the periosteum
Nerves:
The axon of a motor neuron branches and ends in motor end plates on the fiber
Specialized striated fibres called spindles (stretch receptors) form sensory receptors in muscles telling the brain how far the muscle has stretched
Blood Supply to the Head and Neck
- Most arteries in the anterior cervical triangle arise from the common carotid artery or one of the branches of the external carotid artery.
- Most veins in the anterior cervical triangle are tributaries of the large internal jugular vein.
The Common Carotid Arteries
- The right common carotid artery begins at the bifurcation of the brachiocephalic trunk, posterior to the right sternoclavicular joint.
- The left common carotid artery begins arises from the arch of the aorta and ascends into the neck, posterior to the left sternoclavicular joint.
- Each common carotid artery ascends into the neck within the carotid sheath to the level of the superior border of the thyroid cartilage.
- Here it terminates by dividing into the internal and external carotid arteries.
The Internal Carotid Artery
- This is the direct continuation of the common carotid artery and it has no branches in the neck.
- It supplies structures inside the skull.
- The internal carotid arteries are two of the four main arteries that supply blood to the brain.
- Each artery arises from the common carotid at the level of the superior border of the thyroid cartilage.
- It then passes superiorly, almost in a vertical plane, to enter the carotid canal in the petrous part of the temporal bone.
- A plexus of sympathetic fibres accompany it.
- During its course through the neck, the internal carotid artery lies on the longus capitis muscle and the sympathetic trunk.
- The vagus nerve (CN X) lies posterolateral to it.
- The internal carotid artery enters the middle cranial fossa beside the dorsum sellae of the sphenoid bone.
- Within the cranial cavity, the internal carotid artery and its branches supply the hypophysis cerebri (pituitary gland), the orbit, and most of the supratentorial part of the brain.
The External Carotid Arteries
- This vessel begins at the bifurcation of the common carotid, at the level of the superior border of the thyroid cartilage.
- It supplies structures external to the skull.
- The external carotid artery runs posterosuperiorly to the region between the neck of the mandible and the lobule of the auricle.
- It terminates by dividing into two branches, the maxillary and superficial temporal arteries.
- The stems of most of the six branches of the external carotid artery are in the carotid triangle.
The Superior Thyroid Artery
- This is the most inferior of the 3 anterior branches of the external carotid.
- It arises close to the origin of the vessel, just inferior to the greater horn of the hyoid.
- The superior thyroid artery runs anteroinferiorly, deep to the infrahyoid muscles and gives off the superior laryngeal artery. This artery pierces the thyrohyoid membrane in company with the internal laryngeal nerve and supplies the larynx.
The Lingual Artery
- This arises from the external carotid artery as it lies on the middle constrictor muscle of the pharynx.
- It arches superoanteriorly, about 5 mm superior to the tip of the greater horn of the hyoid bone, and then passes deep to the hypoglossal nerve, the stylohyoid muscle, and the posterior belly of digastric muscle.
- It disappears deep to the hyoglossus muscle.
- At the anterior border of this muscle, it turns superiorly and ends by becoming the deep lingual artery.
The Facial Artery
- This arises from the carotid artery either, in common with the lingual artery, or immediately superior to it.
- In the neck the facial artery gives off its important tonsillar branch and branches to the palate and submandibular gland.
- The facial artery then passes superiorly under the cover of the digastric and stylohyoid muscles and the angle of the mandible.
- It loops anteriorly and enters a deep groove in the submandibular gland.
- The facial artery hooks around the inferior border of the mandible and enters the face. Here the pulsation of this artery can be felt (anterior to the masseter muscle).
The Ascending Pharyngeal Artery
- This is the 1st or 2nd branch of the external carotid artery.
- This small vessel ascends on the pharynx, deep to the internal carotid artery.
- It sends branches to the pharynx, prevertebral muscles, middle ear and meninges.
The Occipital Artery
- This arises from the posterior surface of the external carotid near the level of the facial artery.
- It passes posteriorly along the inferior border of the posterior belly of digastric.
- It ends in the posterior part of the scalp.
- During its course, it is superficial to the internal carotid artery and three cranial nerves (CN IX, CN X and CN XI).
The Posterior Auricular Artery
- This is a small posterior branch of the external carotid artery.
- It arises from it at the superior border of the posterior belly of the digastric muscle.
- It ascends posteriorly to the external acoustic meatus and supplies adjacent muscles, the parotid gland, the facial nerve, structures in the temporal bone, the auricle, and the scalp.
The Internal Jugular Vein
- This is usually the largest vein in the neck.
- The internal jugular vein drains blood from the brain and superficial parts of the face and neck.
- Its course corresponds to a line drawn from a point immediately inferior to the external acoustic meatus to the medial end of the clavicle.
- This large vein commences at the jugular foramen in the posterior cranial fossa, as the direct continuation of the sigmoid sinus.
- The dilation at its origin is called the superior bulb of the internal jugular vein.
- From here it runs inferiorly through the neck in the carotid sheath.
- The internal jugular vein leaves the anterior triangle of the neck by passing deep to the SCM muscle.
- Posterior to the sternal end of the clavicle, it unites with the subclavian vein to form the brachiocephalic vein.
- Near its termination is the inferior bulb of the jugular vein contains a bicuspid valve similar to that of the subclavian vein.
- The deep cervical lymph nodes lie along the course of the internal jugular vein, mostly lateral and posterior.
Tributaries of the Internal Jugular Vein
- This large vein is joined at its origin by the: inferior petrosal sinus, the facial, lingual, pharyngeal, superior and middle thyroid veins, and often the occipital vein.
The skull, the skeleton of the head, is the most complex bony structure in the body because it:
- Encloses the brain, which is irregular in shape;
- Houses the organs of special senses for seeing, hearing, tasting, and smelling; and
- Surrounds the openings in to the digestive and respiratory tracts.
- In the anatomical position, the skull is oriented so that the inferior margin of the orbit (eye socket) and the superior margin of the external acoustic meatus (auditory canal) are horizontal. This is called the orbitomenial plane (Frankfort plane).
- The term cranium (L. skull) is sometimes used when referring to the skull without the mandible (lower jaw), but the cranium is often used when referring to the part of the skull containing the brain.
- The superior part is the box-like structure called the calvaria (cranial vault, brain case); the remainder of the cranium, including the maxilla (upper jaw), orbits (eyeball sockets) and nasal cavities, forms the facial skeleton.
- The term skullcap (calotte) refers to the superior part of the calvaria, which is removed during autopsies and dissections. The inferior aspect of the cranium is called the cranial base.
The Scalp
- The scalp consists of five layers of soft tissue.
- It extends from the superior nuchal line on the posterior aspect of the skull of the supraorbital margins.
- Laterally, the scalp extends into the temporal fossa to the level of the zygomatic arches.
Layers of the Scalp
- The scalp proper is composed of three fused layers. It is separated from the pericranium by loose connective tissue.
- Because of this potential areolar cleavage plane, the scalp is fairly mobile.
- Each letter of the word "S C A L P" serves as a memory key for one of the layers of the scalp: Skin, Connective Tissue, Aponeurosis Epicranialis, Loose Areolar Tissue and Pericranium.
Layer 1: Skin
- Hair covers the scalp in most people.
- The skin of the scalp is thin, especially in elderly people, except in the occipital region.
- The skin contains many sweat and sebaceous glands and hair follicles.
- The skin of the scalp has an abundant arterial supply and good venous and lymphatic drainage systems.
Layer 2: Connective Tissue
- This is a thick, subcutaneous layer of connective tissue and is richly vascularised and innervated.
- It attaches the skin to the third layer of the scalp.
- Fat is enclosed in lobules between the connective fibres.
Layer 3: Aponeurosis Epicranialis
- This is a strong membranous sheet that covers the superior aspect of the cranium.
- This aponeurosis is the membranous tendon of the fleshy bellies of the epicranius muscle.
- The epicranius muscle consists of four parts: two occipital bellies, occipitalis and two frontal bellies, frontalis that are connected by the epicranial aponeurosis.
Layer 4: Loose Areolar Tissue
- This is a subaponeurotic layer or areolar or loose connective tissue.
- It is somewhat like a sponge because it contains innumerable potential spaces that are capable of being distended by fluid.
- It is this layer that allows free movement of the scalp proper, composed of layers 1-3.
Layer 5: Pericranium
- This is a dense layer of specialised connective tissue.
- The pericranium is firmly attached to the bones by connective tissue fibres called Sharpey’s fibres, however, they can be fairly easily stripped from the cranial bones of living persons, except where they are continuous with the fibrous tissues of the cranial sutures.
The Paranasal Sinuses
- These sinuses are air-filled extensions of the respiratory part of the nasal cavity.
- They are in the following bones, frontal, ethmoid, sphenoid and the maxilla.
The Frontal Sinuses
- These are located between the outer and inner tables of the frontal bone, posterior to the superciliary arches.
The Ethmoidal Sinuses
- These comprise of several small cavities, called ethmoidal air cells, within the ethmoidal labyrinth (G. labyrinthos, a maze) of the lateral mass of the ethmoid bone.
The Sphenoidal Sinuses
- These occupy a variable amount in the body of the sphenoid bone and may extend into the wings.
The Maxillary Sinuses
- These are the largest pair of paranasal sinuses.
- They are pyramidal-shaped cavities that may occupy the entire bodies of the maxillae.
The Medial Pterygoid Muscle
- This is a thick, quadrilateral muscle that also has two heads or origin.
- It embraces the inferior head of the lateral pterygoid muscle.
- It is located deep to the ramus of the mandible.
- Origin: deep head—medial surface of lateral pterygoid plate and pyramidal process of palatine bone, superficial head—tuberosity of maxilla.
- Insertion: medial surface of ramus of mandible, inferior to mandibular foramen.
- Innervation: mandibular nerve via medial pterygoid nerve.
- It helps to elevate the mandible and closes the jaws.
- Acting together, they help to protrude the mandible.
- Acting alone, it protrudes the side of the jaw.
- Acting alternately, they produce a grinding motion.
Muscles Around the Mouth
- The sphincter of the mouth is orbicularis oris and the dilator muscles radiate outward from the lips like the spokes of a wheel.
Orbicularis Oris Muscle
- This muscle encircles the mouth and is the sphincter of the oral aperture
- This muscle (1) closes the lips, (2) protrudes them and (3) compresses them against the teeth.
- It plays an important role in articulation and mastication. Together with the buccinator muscle, it helps to hold the food between the teeth during mastication.
Zygomaticus Major Muscle
- It extends from the zygomatic bone to the angle of the mouth.
- It draws the corner of the moth superolaterally during smiling and laughing.
Zygomaticus Minor Muscle
- This is a narrow slip of muscle, and passes obliquely from the zygomatic bone to the orbicularis oris.
- It helps raise the upper lip when showing contempt or to deepen the nasolabial sulcus when showing sadness.
The Buccinator Muscle
- This is a thin, flat, rectangular muscle.
- It is attached laterally to the alveolar processes of the maxilla and mandible, opposite the molar teeth and the pterygomandibular raphe.
- Medially, its fibres mingle with those of orbicularis oris.Innervation: the buccal branch of facial.
- It aids mastication and swallowing by pushing the cheeks against the molar teeth during chewing.