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Anatomy

CARTILAGE

There are 3 types:

Hyaline cartilage
Elastic cartilage
Fibrocartilage

Matrix is made up by: Hyaluronic acid

Proteoglycans

 

- In cartilage the protein core of the proteoglycan molecule binds through a linking protein to hyaluronic acid to form a proteoglycan aggregate which binds to the fibres

- In the matrix there are spaces, lacunae in which one to three of the cells of cartilage, chondrocytes, are found

- The matrix around the lacuna is the territorial matrix

- Type II collagen fibrils are embedded in the matrix

- The type of fiber depends on the type of cartilage

- Cartilage is surrounded by perichondrium which is a dense CT

- Apositional growth takes place in the perichondrium

- The fibroblasts of the perichondrium change to elliptic chondroblasts which later change to round chondrocytes

- Interstitial growth takes place around the lacunae

- Nutrients diffuse through the matrix to get to the chondrocytes   this limits the thickness of cartilage

Hyaline cartilage

Found: Rib cartilage,  articulating surfaces,  nose,  larynx, trachea, embryonic skeleton, Articulating cartilage has no perichondrium

 Bluish-white and translucent

Contains type II collagen that is not visible

 

Elastic cartilage

Found:  external auditory canal,  epiglottis

Similar to hyaline except that it contains many elastic fibres ,Yellow in colour,  Can be continuous with hyaline

Fibrocartilage

Found: Intervertebral disk, symphysis pubis

Always associated with dense CT,  Many collagen fibres in the matrix, No perichondrium

- Chondrocytes tend to lie in rows, Can withstand strong forces


-> Most of the facial skeleton is formed by nine bones: four paired (nasal, zygomatic, maxilla, and palatine) and one unpaired (mandible).
-> The calvaria of the new-born infant is large compared with the relatively small fascial skeleton.
-> This results from the small size of the jaws and the almost complete absence of the maxillary and other paranasal sinuses in the new-born skull.
-> These sinuses form large spaces in the adult facial skeleton. As the teeth and sinuses develop during infancy and childhood, the facial bones enlarge.
-> The growth of the maxillae between the ages of 6 and 12 years accounts for the vertical elongation of the child’s face.


The Nasal Bones 

-> These bones may be felt easily because they form the bridge of the nose.
-> The right and left nasal bones articulate with each other at the internasal suture.
-> They also articulate with the frontal bones, the maxillae, and the ethmoid bones.
-> The mobility of the anteroinferior portion of the nose, supported only by cartilages, serves as a partial protection against injure (e.g., a punch in the nose). However, a hard blow to the anterosuperior bony portion of the nose may fracture the nasal bones (broken nose).
-> Often the bones are displaced sideways and/or posteriorly.

The Maxillae 

-> The skeleton of the face between the mouth and the eyes is formed by the two maxillae.
-> They surround the anterior nasal apertures and are united in the medial plane at the intermaxillary suture to form the maxilla (upper jaw).
-> This suture is also visible in the hard palate, where the palatine processes of the maxillae unite.
-> Each adult maxilla consists of: a hollow body that contains a large maxillary sinus; a zygomatic process that articulates with its mate on the other side to form most of the hard palate; and alveolar processes that form sockets for the maxillary (upper) teeth.
-> The maxillae also articulate with the vomer, lacrimal, sphenoid, and palatine bones.
-> The body of the maxilla has a nasal surface that contributes to the lateral wall of the nasal cavity; an orbital surface that forms most of the floor of the orbit; an infratemporal surface that forms the anterior wall of the infratemporal fossa; and an anterior surface that faces partly anteriorly and partly anterolaterally and is covered buy facial muscles.
-> The relatively large infraorbital foramen, which faces inferomedially, is located about 1 cm inferior to the infraorbital margin; it transmits the infraorbital nerve and vessels.
-> The incisive fossa is a shallow concavity overlying the roots of the incisor teeth, just a shallow concavity overlying the roots of the incisor teeth, just inferior to the nasal cavity. This fossa is the injection site for anaesthesia of the maxillary incisor teeth.
-> If infected maxillary teeth are removed, the bone of the alveolar processes of the maxillae begins to be reabsorbed. As a result, the maxilla becomes smaller and the shape of the face changes.
-> Owing to absorption of the alveolar processes, there is a marked reduction in the height of the lower face, which produces deep creases in the facial skin that pass posteriorly from the corners of the mouth.


The Mandible 

-> This is a U-shaped bone and forms the skeleton of the lower jaw and the inferior part of the face. It is the largest and strongest facial bone.
-> The mandibular (lower) teeth project superiorly from their sockets in the alveolar processes.
-> The mandible (L. mandere, to masticate) consists of two parts: a horizontal part called the body, and two vertical oblong parts, called rami.
-> Each ramus ascends almost vertically from the posterior aspect of the body.
-> The superior part of the ramus has two processes: a posterior condylar process with a head or condyle and a neck, and a sharp anterior coronoid process.
-> The condylar process is separated from the coronoid process by the mandibular notch, which forms the concave superior border of the mandible.
-> Viewed from the superior aspect, the mandible is horseshoe-shaped, whereas each half is L-shaped when viewed laterally.
-> The rami and body meet posteriorly at the angle of the mandible.
-> Inferior to the second premolar tooth on each side of the mandible is a mental foramen (L. mentum, chin) for transmission of the mental vessels and the mental nerve.
-> In the anatomical position, the rami of the mandible are almost vertical, except in infants and in edentulous (toothless) adults.
-> On the internal aspect of the ramus, there is a large mandibular foramen.
-> It is the oblong entrance to the mandibular canal that transmits the inferior alveolar vessels and nerve to the roots of the mandibular teeth.
-> Branches of these vessels and the mental nerve emerge from the mandibular canal at the mental foramen.
-> Running inferiorly and slightly anteriorly on the internal surface of the mandible from the mandibular foramen is a small mylohyoid groove (sulcus), which indicates the course taken by the mylohyoid nerve and vessels.
-> These structures arise from the inferior alveolar nerve and vessels, just before they enter the mandibular foramen.
-> The internal surface of the mandible is divided into two areas by the mylohyoid line, which commences posterior to the third molar tooth. -> Just superior to the anterior end of the mylohyoid line are two small, sharp mental spines (genial tubercles), which serve as attachments for the genioglssus muscles.

The Zygomatic Bones 

-> The prominences of the cheeks (L. mala), the anterolateral rims and much of the infraorbital margins of the orbits, are formed by the zygomatic bones (malar bones, cheekbones).
-> They articulate with the frontal, maxilla, sphenoid, and temporal bones.
-> The frontal process of the zygomatic bone passes superiorly, where it forms the lateral border of the orbit (eye socket) and articulates with the frontal bone at the lateral edge of the supraorbital margin.
-> The zygomatic bones articulate medially with the greater wings of the sphenoid bone. The site of their articulation may be observed on the lateral wall of the orbit.
-> On the anterolateral aspect of the zygomatic bone near the infraorbital margin is a small zygomaticofacial foramen for the nerve and vessels of the same name.
-> The posterior surface of the zygomatic bone near the base of its frontal process is pierced by a small zygomaticotemporal foramen for the nerve of the same name.
-> The zygomaticofacial and zygomaticotemporal nerves, leaving the orbit through the previously named foramina, enter the zygomatic bone through small zygomaticoorbital foramina that pierces it orbital surface.
-> The temporal process of the zygomatic bone unites with the zygomatic process of the temporal bone to form the zygomatic arch.
-> This arch can be easily palpated on the side of the head, posterior to the zygomatic prominence (malar eminence) at the inferior boundary of the temporal fossa (temple).
-> The zygomatic arches form one of the useful landmarks for determining the location of the pterion. These arches are especially prominent in emaciated persons.
-> A horizontal plane passing medially from the zygomatic arch separates the temporal fossa superiorly from the infratemporal fossa inferiorly.

Other Bones

There are several other, very important bones in the skull, including the palatine bone, ethmoid bone, vomer, inferior concha and the ossicles of the ear (malleus, incus and stapes). These, however, are covered to greater detail where they are relevant in the head (e.g., ethmoid bone with the orbit and nasal cavity).

 

The External Ear

  • The auricle (L. auris, ear) is the visible, shell-like part of the external ear.
  • It consists of a single elastic cartilage that is covered on both surfaces with thin, hairy skin.
  • The external ear contains hairs, sweat glands, and sebaceous glands.
  • The cartilage is irregularly ridged and hollowed, which gives the auricle its shell-like form.
  • It also shapes the orifice of the external acoustic meatus.

 

The Ear Lobule

  • The ear lobule (earlobe) consists of fibrous tissue, fat and blood vessels that are covered with skin.
  • The arteries are derived mainly from the posterior auricular artery and the superficial temporal artery.
  • The skin of the auricle is supplied by the great auricular and auriculotemporal nerves.
  • The great auricular nerve supplies the superior surface and the lateral surface inferior to the external acoustic meatus with nerve fibres from C2.
  • The auriculotemporal nerve supplies the skin of the auricle superior to the external acoustic meatus.

The External Acoustic Meatus

  • This passage extends from the concha (L. shell) of the auricle to the tympanic membrane (L. tympanum, tambourine). It is about 2.5 cm long in adults.
  • The lateral 1/3 of the S-shaped canal is cartilaginous, whereas its medial 2/3 is bony.
  • The lateral third of the meatus is lined with the skin of the auricle and contains hair follicles, sebaceous glands, and ceruminous glands.
  • The latter glands produce cerumen (L. cera, wax).
  • The medial two-thirds of the meatus is lined with very thin skin that is continuous with the external layer of the tympanic membrane.
  • The lateral end of the meatus is the widest part. It has the diameter about that of a pencil.
  • The meatus becomes narrow at its medial end, about 4 mm from the tympanic membrane.
  • The constricted bony part is called the isthmus.
  • Innervation of the external acoustic meatus is derived from three cranial nerves:
  1. The auricular branch of the auriculotemporal nerve (derived from the mandibular, CN V3).
  2. The facial nerve (CN VII) by the branches from the tympanic plexus.
  3. The auricular branch of the vagus nerve (CN X).

The Tympanic Membrane

  • This is a thin, semi-transparent, oval membrane at the medial end of the external acoustic meatus.
  • It forms a partition between the external and middle ears.
  • The tympanic membrane is a thin fibrous membrane, that is covered with very thin skin externally and mucous membrane internally.
  • The tympanic membrane shows a concavity toward the meatus with a central depression, the umbo, which is formed by the end of the handle of the malleus.
  • From the umbo, a bright area referred to as the cone of light, radiates anteroinferiorly.
  • The external surface of the tympanic membrane is supplied by the auriculotemporal nerve.
  • Some innervation is supplied by a small auricular branch of the vagus nerve (CN X); this nerve may also contain some glossopharyngeal and facial nerve fibres.

  • The six muscles rotate the eyeball in the orbit around three axes (sagittal, horizontal and vertical).
  • The action of the muscles can be deduced by their site of insertion on the eyeball.
Muscle Action(s) on the Eyeball Nerve Supply
Medial Rectus Adducts CN III
Lateral Rectus Abducts CN VI
Superior Rectus Elevates, adducts, and medially rotates CN III
Inferior Rectus Depresses, adducts, and laterally rotates CN III
Superior Oblique Depresses, abducts, and medially rotates CN IV
Inferior Oblique Elevates, abducts, and laterally rotates CN III

Skeletal Muscle:  1-40 cm long fibres, 10- 60 µm thick, according to myoglobin content there are:

Red fibres: lots of myoglobin, many mitochondriam slow twitching - tire slowly

White fibres:  less myoglobin,  less mitochondria, fast twitching - tire quickly

Intermediate fibres:

mixture of 2 above

Most muscles have all three - in varying ratios

Structure of skeletal muscle:

Light Microscopy:  Many nuclei - 35/mm,  Nuclei are oval - situated peripheral,  Dark and light bands

Electron Microscopy: Two types of myofilaments

Actin

- 5,6 nm

 3 components:

 -actin monomers,  

 -tropomyosin - 7 actin molecules long

- troponin

 actin monomers form 2 threats that spiral

- tropomyosin - lie in the groove of the spiral

- troponin - attach every 40 nm

- one end attach to the Z line

- other end goes to the middle of the sarcomere

- Z line consists of á actinin

Myosin:

- 15 nm

- 1,6 µm long

- The molecule has a head and a tail

- tails are parallel

- heads project in a spiral

- in the middle is a thickening

- thin threats bind the myosin at thickening (M line)

Contraction:

A - band stays the same, I - band, H - bands become narrower

Myosin heads ratchet on the actin molecule

Sarcolemma: 9 nm thick,  invaginate to form T-tubule,

 myofibrils - attach to the sarcolemma

Sarcoplasmic Reticulum:

specialized smooth EPR,  Consists of T-tubules, terminal sisternae and sarcotubules

It is speculated that there are gap junctions between the T-tubule and terminal sisterna

An impulse is carried into the fiber by the T-tubule from where it goes to the rest of the sarcoplasmic reticulum

Connective tissue coverings of the muscle

Endomycium around fibres, perimycium around bundles and epimycium around the whole muscle

Blood vessels and nerves in CT

CT goes over into tendon or aponeurosis which attaches to the periosteum

Nerves:

The axon of a motor neuron branches and ends in motor end plates on the fiber

Specialized striated fibres called spindles (stretch receptors) form sensory receptors in muscles telling the brain how far the muscle has stretched

Structure of the Nasal Septum

  • This part bony, part cartilaginous septum divides the chamber of the nose into two narrow nasal cavities.
  • The bony part of the septum is usually located in the median plane until age 7; thereafter, it often deviates to one side, usually the right.
  • The nasal septum has three main components: (1) the perpendicular plate of the ethmoid bone; (2) the vomer, and (3) the septal cartilage.
  • The perpendicular plate, which forms the superior part of the septum, is very thin and descends from the cribiform plate of the ethmoid bone.
  • The vomer, which forms the posteroinferior part of the septum, is a thin, flat bone. It articulates with the sphenoid, maxilla and palatine bones.

Movements of the Temporomandibular Joint

  • The two movements that occur at this joint are anterior gliding and a hinge-like rotation.
  • When the mandible is depressed during opening of the mouth, the head of the mandible and articular disc move anteriorly on the articular surface until the head lies inferior to the articular tubercle.
  • As this anterior gliding occurs, the head of the mandible rotates on the inferior surface of the articular disc.
  • This permits simple chewing or grinding movements over a small range.
  • Movements that are seen in this joint are: depression, elevation, protrusion, retraction and grinding

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