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Anatomy - NEETMDS- courses
NEET MDS Lessons
Anatomy

Cardiac Muscle

Fibres anastomose through cross bridges

Fibres are short, connected end to end at intercalated discs, also striated,  contract automatically

Light microscopic Structure:

Short fibres connected at intercalated disks,  85 - 100 µm long,  15 µm

same bands as in skeletal muscle,  1 or 2 nuclei - oval and central,  in perinuclear area is a sarcoplasmic reticulum, intercalated discs lie at the Z line

Electron microscopic structure:

 Between myofibrils lie the mitochondria,  2,5 µm long mitochondria,  dense cristae

and are as long as the sarcomere, fibres have more glycogen than skeletal muscle fibres

myofilaments, actin and myosin are the same as in skeletal muscle,  the sarcoplasmic reticulum differs in that there is no terminal sisterna. The sarcotubules end in little feet that

sit on the T-tubule

Intercalated Disc:

on Z lines,  fibres interdigitate,

 3 types of junctions in the disc

Transverse Part:

zonula adherens

desmosomes

Lateral Part:

Gap junctions (nexus) - for impulse transfer

Mechanism of Contraction:

slide - ratchet like in skeletal muscle, certain fibres are modified for conduction,  Impulses spread from cell to cell through gap junctions,  Purkinje cells are found in the AV bundle

they have less myofibrils,  lots of glycogen and intercalated discs

Connective tissue coverings:

Only endomycium in cardiac muscle,  Blood vessels, lymph vessels and nerves lie in the endomycium

 

The Oral Cavity

  • The oral cavity (mouth) consists of two parts: the vestibule and the mouth proper.
  • The vestibule is the slit-like spaced between the cheeks and the lips and the teeth and gingivae.
  • It is the entrance of the digestive tract and is also used for breathing.
  • The vestibule communicates with the exterior through the orifice of the mouth.
  • The oral cavity is bounded:
  • Externally: by the cheeks and lips.
  • Roof of oral cavity: formed by the palate.
  • Posteriorly: the oral cavity communicates with the oropharynx.

The Muscles of Facial Expression

  • These lie in the subcutaneous tissue and are attached to the skin of the face.
  • They enable us to move our skin and change our facial expression. They produce their effects by pulling on the skin but do not move the facial skeleton.
  • These muscles surround the facial orifices and act as sphincters and dilators.
  • All facial muscles receive their innervation from the branches of the facial nerve (CN VII)-temporal, zygomatic, buccal, marginal mandibular, cervical.

The Nose

  • The nose is the superior part of the respiratory tract and contains the peripheral organ of smell.
  • It is divided into right and left nasal cavities by the nasal septum.
  • The nasal cavity is divided into the olfactory area and the respiratory area.

The Skeleton of the Nose

  • The immovable bridge of the nose, the superior bony part of the nose, consists of the nasal bones, the frontal processes of the maxillae, and the nasal part of the frontal bones.
  • The movable cartilaginous part consists of five main cartilages and a few smaller ones.
  • The U-shaped alar nasal cartilages are free and movable.
  • They dilate and constrict the external nares when the muscles acting on the external nose contract.

 

The Nasal Cavities

  • The nasal cavities are entered through the anterior nares or nostrils.
  • They open into the nasopharynx through the choanae.

 

The Roof and Floor of the Nasal Cavity

  • The roof is curved and narrow, except at the posterior end.
  • The floor is wider than the roof.
  • It is formed from the palatine process of the maxilla and the horizontal plate of the palatine bone.

 

The Walls of the Nasal Cavity

  • The medial wall is formed by the nasal septum; it is usually smooth.
  • The lateral wall is uneven owing to the three longitudinal, scroll-shaped elevations, called the conchae (L. shells) or turbinates (L. shaped like a top).
  • These elevations are called the superior, middle and inferior conchae according to their position.
  • The superior and middle conchae are parts of the ethmoid bone, whereas the inferior conchae are separate bones.
  • The inferior and middle conchae project medially and inferiorly, producing air passageways called the inferior and middle meatus (L. passage). Note: the plural of "meatus" is the same as the singular.
  • The short superior conchae conceal the superior meatus.
  • The space posterosuperior to the superior concha is called the sphenoethmoidal recess.

Classification

Epitheliums can be classified on appearance or on function

Classification based on appearance

- Simple - one layer of cells

- Pseudostratified - looks like more than one layer but is not

- Stratified - more than one layer of cells

Simple epitheliums

Simple squamous epithelium

 Cells are flat with bulging or flat nuclei.  Lines the insides of lung alveoli and certain ducts in the kidney

 Forms serous membranes called mesothelium that line cavities like: pericardial ,  peritoneal,  plural

 Lines blood vessels - known as endothelium

Simple cuboidal epithelium

It appears square in cross section,  Found in: - Ducts of salivary glands,  Follicles of the thyroid gland,  Pigment layer in the eye,  Collecting ducts of the kidney, In the middle ear is ciliated type.

Simple columnar

  • Lines the gastrointestinal tract from the stomach to the anal canal,  Some columnar cells have a  secretory function – stomach, peg cells in the oviduct,  Some columnar cells have microvilli on their free border (striated border) – gall bladder, duodenum
  • Microvilli increase the surface area for absorption
  • Some columnar cells have cilia – oviduct, smaller bronchi
  • Cilia transport particles

Pseudostratified

Appears as stratified epithelium but all cells are in contact with the basement membrane.  Has a thick basement membrane. Different cell types make up this epithelium,  Cells that can be found in this type of epithelium are:

  • Columnar cells with cilia or microvilli.
  • Basal cells that do not reach the surface.
  • Goblet cells that secrete mucous.
  • Found in the trachea, epididymus, ductus deferens and female urethra

Stratified epithelium

Classified according to the shape of the surface cells

Stratified squamous epithelium

Has a basal layer that varies from cuboidal to columnar cells that divide to form new cells. Two types are found:

Keratinized:  Mostly forms a dry covering, The middle layers consists of cells that are forming- and filling up with keratin. The superficial cells form a tough non living layer of keratin,  Keratin is a type of protein,  The skin is of this type has  thick skin - found on the hand palms and soles of the feet,  thin skin - found on the rest of the body

Non-keratinized:  Top layer of cells are living cells with nuclei  Forms a wet covering,  The middle layers are polyhedral,  The surface layer consists of flat squamous cells

  • Is found in:  mouth,  oesophagus,  vagina

Stratified cuboidal epithelium

Found: - in the ducts of sweat glands

Stratified columnar epithelium

Found at the back of the eyelid (conjunctiva)

Transitional epithelium

- Sometimes the surface cells are squamous, sometimes cuboidal and sometimes columnar

- The superficial cells are called umbrella cells because they can open and close like umbrellas, when the epithelium stretch and shrink

- Umbrella cells can have 2 nuclei

- Found in the bladder and ureter

-> This bone forms much of the base and posterior aspect of the skull.
-> It has a large opening called the foramen magnum, through which the cranial cavity communicates with the vertebral canal.
-> It is also where the spinal cord becomes continuous with the medulla (oblongata) of the brain stem.
-> The occipital bone is saucer-shaped and can be divided into four parts: a squamous part (squama), a basilar part (basioccipital part), and two lateral parts (condylar parts).
-> These four parts develop separately around the foramen magnum and unite at about the age of 6 years to form one bone.
-> On the inferior surfaces of the lateral parts of the occipital bone are occipital condyles, where the skull articulates with C1 vertebra (the atlas) at the atlanto-occipital joints.
-> The internal aspect of the squamous part of the occipital bone is divided into four fossae: the superior two for the occipital poles of the cerebral hemispheres, and the inferior two, called cerebellar fossae, for the cerebellar hemispheres.

 

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