• Skull 
  Cranium
  o    Superior portion formed by the frontal. parietal, and occipital bones
  o    Lateral portions formed by the temporal and sphenoid bones
  o    Cranial base formed by the temporal. sphenoid, and ethmoid bones
  o    Fontanels-soft spots in which ossification is incomplete at birth

  Frontal bone
  o    Forms the forehead
  o    Contains the frontal sinuses
  o    Forms the roof of the orbits
  o    Union with the parietal bones forms the coronal suture

  Parietal bones
  o    Union with the occipital bone forms the lambdoid suture
  o    Union with the temporal bone forms the squamous suture
  o    Union with the sphenoid bone forms the coronal suture

  Temporal bones
  o    Contains the external auditory meatus and middle and inner ear structures
  o    Squamous portion-above the meatus: zygomatic process-articulates with the zygoma
  o    to form the zygomatic arch 

  •    Petrous portion
  o    Contains organs of hearing and equilibrium 
  o    Prominent elevation on the floor of the cranium

  •    Mastoid portion
  o    Protuberance behind the ear

  o    Mastoid process
  •    Glenoid fossa-articulates with the condyle on the mandible
  •    Styloid process-anterior to the mastoid process; several neck muscles attach here
  •    Stylomastoid foramen-located between the styloid and mastoid processes; facial nerve emerges through this opening
  •    Jugular foramen-located between the petrous portion and the occipital bone: cranial nerves IX. X, and XI exit
   

The Layers of the Pharyngeal Wall

• The pharyngeal wall is composed of 5 layers. From internal to external, they are as follows.

• Mucous membrane: this lines the pharynx and is continuous with all chambers with which it communicates.

• Submucosa

• Pharyngobasilar fascia: this is a fibrous layer that is attached to the skull.

• Muscular layer: this is composed of inner longitudinal and outer circular parts.

• Buccopharyngeal fascia: this is a loose connective tissue layer.
• This fascia is continuous with the fascia covering the buccinator and pharyngeal muscle.
• It contains the pharyngeal plexus of nerves and veins.

The Frontalis Muscle

• The frontalis muscle is part of the scalp muscle called the occipitalfrontalis.
• The frontalis elevates the forehead, giving the face a surprised look, and produces transverse wrinkles in the forehead when one frowns.

Endochondral ossification

• A cartilage model exists
• Through intramembraneous ossification in the perichondrium a collar of bone forms around the middle part of the cartilage model
• The perichondrium change to a periostium
• The bone collar cuts off the nutrient and oxygen supply to the chondrocytes in the cartilage model
• The chondrocytes then increase in size and resorb the surrounding cartilage matrix until only thin vertical septae of matrix are left over
• These thin plates then calcify after which the chondrocytes die
• The osteoclasts make holes in the bone collar through which blood vessels can now enter the cavities left behind by the chondrocytes
• With the blood vessels osteoprogenitor cells enter the tissue
• They position themselves on the calcified cartilage septae, change into osteoblasts and start to deposit bone to form trabeculae
• In the mean time the periosteum is depositing bone on the outside of the bone collar making it thicker and thicker
• The trabeculae,consisting of a core of calcified cartilage with bone deposited on top of it, are eventually resorbed by osteoclasts to form the marrow cavity
• The area where this happens is the primary ossification centre and lies in what is called the diaphysis (shaft)
• This process spreads in two directions towards the two ends of the bone the epiphysis
• In the two ends (heads) of the bone a similar process takes place
• A secondary ossification centre develops from where ossification spreads radially
• Here no bone collar forms
• The outer layer of the original cartilage remains behind to form the articulating cartilage
• Between the primary and the secondary ossification centers two epiphyseal cartilage plates remain
• This is where the bone grows in length

• From the epiphyseal cartilage plate towards the diaphysis a number of zones can be identified:

 Resting zone of cartilage

 Hyaline cartilage

 Proliferation zone

 Chondrocytes divide to form columns of cells that mature.

Hypertrophic cartilage zone

 Chondrocytes become larger, accumulate glycogen, resorb the surrounding matrix so that only thin septae of cartilage remain 

Calcification and degeneration zone

The thin septae of cartilage become calcified.

The calsified septae cut off the nutrient supply to the chondrocytes so subsequently they die.

Ossification zone.

Osteoclasts make openings in the bone collar through which blood vessels then invade the spaces left vacant by the chondrocytes that died.

Osteoprogenitor cells come in with the blood and position themselves on the calcified cartilage

septae, change into osteoblasts and start to deposit bone.

 When osteoblasts become trapped in bone they change to osteocytes.

Growth and remodeling of bone

Long bones become longer because of growth at the epiphyseal plates

They become wider because of bone formed by the periosteum

The marrow cavity becomes bigger because of resorbtion by the osteoclasts

Fracture repair

When bone is fractured a blood clot forms

 Macrophages then remove the clot, remaining osteocytes and damaged bone matrix

The periosteum and endosteum produce osteoprogenitor cells that form a cellular tissue in the fracture area

 Intramembranous and endochondral ossification then take place in this area forming trabeculae.

Trabeculae connect the two ends of the broken bone to form a callus

Remodelling then takes place to restore the bone as it was

Joints

The capsule of a joint seals off the articular cavity,  

The capsule has two layers

 fibrous (outer)

synovial (inner)

The synovial layer is lined by squamous or cuboidal epithelial cells,  Under this layer is a layer of loose or dense CT, The lining cells consists of two types:

- A cells

- B cells

They secrete the synovial fluid

They are different stages of the same cell, They are also phagocytic., The articular cartilage has fibres that run perpendicular to the bone and then turn to run parallel to the surface

Hip

Constitutes the pelvic girdle
United with the vertebral column
Union of three parts that is marked by a cup shaped cavity (acetabulum) Ilium
•    Prominence of the hip
•    Superior border is the crest
•    Anterosuperior spine-projection at the anterior tip of the crest
•    Corresponding projections on the posterior part are the posterosuperior and posteroinferior iliac spines
•    Greater sciatic notch-located beneath the posterior part
•    Most is a smooth concavity (iliac fossa)
•    Posteriorly it is rough and articulates with the sacrum in the formation of the sacroiliac joint

Pubic bone

Anterior part of the innominate bone
Symphysis pubic-joining of the two pubic bones at the midline
Body and two rami 
•    Body forms one fifth of the acetabulum
•    Superior ramis extends from the body to the median plane: superior border forms the pubic crest
•    Inferior ramus extends downward and meets with the ischium
•    Pubic arch is formed by the inferior rami of both pubic hones

Ischium
    Forms the lower and back part of the innominate bone
    Body
•    Forms two fifths of the accrabulum
•    Ischial tuberosiry-supports the body in a sitting position
•    Ramus-passes upward to join the inferior ramus of rhe pubis; known as rhe obturator foramen

Pelvis

Fanned by the right and left hip bones, sacrum, and coccyx

Greater pelvis

o    Bounded by the ilia and lower lumbar vertebrae
o    Gives support to the abdominal viscera

Lesser pelvis

o    Brim of the pelvis corresponds to the sacral promontory
o    Inferior outlet is bounded by the tip of the coccyx, ischial tuberosities, and inferior rami of the pubic bones

Female pelvis

o    Shows adaptations related to functions as a birth canal Wide outlet
o    Angle of the pubic arch is obtuse

Male pelvis

o    Shows adaptations that contribute to power and speed
o    Heart-shaped outlet
o    Angle of the pubic arch is acute

Thigh

Femur-longest and strongest bone of the body
Proximal end has a rounded head that articulates with the acetabulum
Constricted portion-the neck
Greater and lesser trochanters
Slightly arched shaft; is concave posteriorly
o    Linea aspera-strengthened by this prominent ridge
o    Site of attachment for several muscles
Distal end has two condyles separated on the posterior side by the intercondyloid notch

Knee cap

Patella-sesamoid bone
Embedded in the tendon of the quadriceps muscle
Articulates with the femur

Leg

Tibia-medial bone
o    Proximal end has two condyles that articulate with the femur
o    Triangular shaft

    Anterior-shin
    Posterior-soleal line
    Distal-medial malleolus that articulates with the latus to form the ankle joint
Fibula-lateral bone
o    Articulates with the lateral condyle of the tibia but does not enter the knee joint
o    Distal end projects as the lateral malleolus

Ankle, foot, and toes

Adapted for supporting weight but similar in structure to the hand

Talus

o    Occupies the uppennost and central position in the tarsus
o    Distributes the body weight from the tibia above to the other tarsal bones
Calcaneus (heel)-Iocated beneath the talus
Navicular-located in front of the talus on the medial side; articulates with three cuneifonn bones distally
Cuboid-lies along the lateral border of the navicular bone

Metatarsals
o    First, second, and third p1etatarsals lie in front of the three cuneifonn bones
o    (2) Fourth and fifth metatarsals lie in front of the cuboid bone

Phalanges

o    Distal to the metatarsals
o    (2) Two in the great toe; three in each of the other four toes .

Longitudinal arches in the foot (2)

o    Lateral-fonned by the calcaneus, talus, cuboid, and fourth and fifth metatarsal bones
o    Medial-fonned by the calcaneus, talus, navicular, cuneifonn, and first, second, and third metatarsal bones

Transverse arches-formed by the tarsal and metatarsal bones

The Nose

• The nose is the superior part of the respiratory tract and contains the peripheral organ of smell.
• It is divided into right and left nasal cavities by the nasal septum.
• The nasal cavity is divided into the olfactory area and the respiratory area.