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Anatomy - NEETMDS- courses
NEET MDS Lessons
Anatomy

Eye 

At week 4, two depressions are evident on each of the forebrain hemispheres.  As the anterior neural fold closes, the optic pits elongate to form the optic vesicles.  The optic vesicles remain connected to the forebrain by optic stalks. 
The invagination of the optic vesicles forms a bilayered optic cup.  The bilayered cup becomes the dual layered retina (neural and pigmented layer)
Surface ectoderm forms the lens placode, which invaginates with the optic cup.
The optic stalk is deficient ventrally to contain choroids fissure to allow blood vessels into the eye (hyaloid artery).  The artery feeds the growing lens, but will its distal portion will eventually degenerate such that the adult lens receives no hyaloid vasculature.
At the 7th week, the choroids fissure closes and walls fuse as the retinal nerve get bigger.
The anterior rim of the optic vesicles forms the retina and iris.  The iris is an outgrowth of the distal edge of the retina.
Optic vesicles induces/maintains the development of the lens vesicle, which forms the definitive lens.  Following separation of the lens vesicle from the surface ectoderm, the cornea develops in the anterior 1/5th of the eye.
The lens and retina are surrounded by mesenchyme which forms a tough connective tissue, the sclera, that is continuous with the dura mater around the optic nerve.  
Iridopupillary membrane forms to separate the anterior and posterior chambers of the eye.  The membrane breaks down to allow for the pupil
Mesenchyme surrounding the forming eye forms musculature (ciliary muscles and pupillary muscles – from somitomeres 1 and 2; innervated by CN III), supportive connective tissue elements and vasculature.


Eyelids

Formed by an outgrowth of ectoderm that is fused at its midline in the 2nd trimester, but later reopen.

The Oropharynx

  • The oral part of the pharynx has a digestive function.
  • It is continuous with the oral cavity through the oropharyngeal isthmus.
  • The oropharynx is bounded by the soft palate superiorly, the base of the tongue inferiorly, and the palatoglossal and palatopharyngeal arches laterally.
  • It extends from the soft palate to the superior border of the epiglottis.

 

The Palatine Tonsils

  • These are usually referred to as "the tonsils".
  • They are collections of lymphoid tissue the lie on each side of the oropharynx in the triangular interval between the palatine arches.
  • The palatine tonsils vary in size from person to person.
  • In children, the palatine tonsils tend to be large, whereas in older persons they are usual small and inconspicuous.
  • The visible part of the tonsil is no guide to its actual size because much of it may be hidden by the tongue and buried in the soft palate.

The Hard Palate

  • The anterior bony part of the palate is formed by the palatine process of the maxillae and the horizontal plates of the palatine bones.
  • Anteriorly and laterally, the hard palate is bounded by the alveolar processes and the gingivae.
  • Posteriorly, the hard palate is continuous with the soft palate.
  • The incisive foramen is the mouth of the incisive canal.
  • This foramen is located posterior to the maxillary central incisor teeth.
  • This foramen is the common opening for the right and left incisive canals.
  • The incisive canal and foramen transmit the nasopalatine nerve and the terminal branches of the sphenopalatine artery.
  • Medial to the third molar tooth, the greater palatine foramen pierces the lateral border of the bony palate.
  • The greater palatine vessels and nerve emerge from this foramen and run anteriorly into two grooves on the palate.
  • The lesser palatine foramen transmits the lesser palatine nerve and vessels.
  • This runs to the soft palate and adjacent structures.

The Masseter Muscle

  • This is a quadrangular muscle that covers the lateral aspect of the ramus and the coronoid process of the mandible.
  • Origin: inferior border and medial surface of zygomatic arch.
  • Insertion: lateral surface of ramus of mandible and its coronoid process.
  • Innervation: mandibular nerve via masseteric nerve that enters its deep surface.
  • It elevates and protrudes the mandible, closes the jaws and the deep fibres retrude it.

The Ear

  • The ear contains the vestibulocochlear organ and consists of three main parts: external, middle, and internal.
  • It has two functions, balance and hearing.
  • The tympanic membrane (eardrum) separates the external ear from the middle ear.
  • The auditory tube joins the middle ear or tympanic cavity to the nasopharynx.

Muscles of the Pharynx

  • This consists of three constrictor muscles and three muscles that descend from the styloid process, the cartilaginous part of the auditory tube and the soft palate.

External Muscles of the Pharynx 

  • The paired superior, middle, and inferior constrictor muscles form the external circular part of the muscular layer of the wall.
  • These muscles overlap each other and are arranged so that the superior one is innermost and the inferior one is outermost.
  • These muscles contract involuntarily in a way that results in contraction taking place sequentially from the superior to inferior end of the pharynx.
  • This action propels food into the oesophagus.
  • All three constrictors of the pharynx are supplied by the pharyngeal plexus of nerves, which lies on the lateral wall of the pharynx, mainly on the middle constrictor of the pharynx.
  • This plexus is formed by pharyngeal branches of the glossopharyngeal (CN IX) and vagus (CN X) nerves.

The Superior Constrictor Muscle

  • Origin: pterygoid hamulus, pterygomandibular raphe, posterior end of the mylohyoid line of the mandible, and side of tongue.
  • Insertion: median raphe of pharynx and pharyngeal tubercle.
  • Innervation: though the pharyngeal plexus of nerves.
  • The pterygomandibular raphe is the fibrous line of junction between the buccinator and superior constrictor muscles.

The Middle Constrictor Muscle

  • Origin: stylohyoid ligament and greater and lesser horns of hyoid bone.
  • Insertion: median raphe of pharynx.
  • Innervation: through the pharyngeal plexus of nerves.

The Inferior Constrictor Muscle

  • Origin: oblique line of thyroid cartilage and side of cricoid cartilage.
  • Insertion: median raphe of pharynx.
  • Innervation: through the pharyngeal plexus of nerves.
  • The fibres arising from the cricoid cartilage are believed to act as a sphincter, preventing air from entering the oesophagus. 

Gaps in the Pharyngeal Musculature

  • The overlapping arrangement of the three constrictor muscles leaves 4 deficiencies or gaps in the pharyngeal musculature.
  • Various structures enter and leave the pharynx through these gaps.
  • Superior to the superior constrictor muscle, the levator veli palatini muscle, the auditory tube, and the ascending palatine artery pass through a gap between the superior constrictor muscle and the skull.
  • Superior to the superior border of the superior constrictor, the pharyngobasilar fascia blends with the buccopharyngeal fascia to form, with the mucous membrane, the thin wall of the pharyngeal recess.
  • Between the superior and middle constrictor muscles, the gateway to the mouth, though which pass the stylopharyngeus muscle, the glossopharyngeal nerve (CN IX), and the stylohyoid ligament.
  • Between the middle and inferior constrictor muscles, the internal laryngeal nerve and the superior laryngeal artery and vein pass to the larynx.
  • Inferior to the inferior constrictor muscles, the recurrent laryngeal nerve and inferior laryngeal artery pass superiorly into the larynx.

  • Cartilage model is covered with perichondrium that is converted to periosteum

  • Diaphysis-central shaft
  • Epiphysis-located at either end of the diaphysis
  • Growth in length of the bone is provided by the emetaphyseal plate located between the epiphyseal cartilage and the diaphysis
  • Blood capillaries and the mesenchymal cells infiltrate the spaces left by the destroyed chondrocytes

  • Osteoblasts are derived from the undifferentiated cells; form an osseous matrix in the cartilage
  • Bone appears at the site where there was cartilage

      Microscopic structure

  • Compact bone is found on the exterior of all bones; canceIlous bone is found in the interior
  • Surface of compact bone is covered by periosteum that is attached by Sharpey's fibers
  • Blood vessels enter the periosteum via Volkmann's canals and then enter the haversian canals that are formed by the canaliculi and lacunae
  •  

  • Marrow
    • FiIls spaces of spongy bone
    • Contains blood vessels and blood ceIls in various stages of development
    • Types
  • Red bone marrow
    • Formation of red blood ceIls (RBCs) and some white blood cells (WBCs) in this location
    • Predominate type of marrow in newborn
    • Found in spongy bone of adults (sternum, ribs, vertebrae, and proximal epiphyses of long bones)
  •  Yellow bone marrow
    • Fatty marrow
    • Generally replaces red bone marrow in the adult, except in areas mentioned above
  •  
  • Ossification is completed as the proximal epiphysis joins with the diaphysis between the twentieth and twenty-fifth year

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