A. Anatomic position-erect body position with the arms at the sides and the palms  upward

B. Plane or section

1. Definition-imaginary flat surface formed by an extension through an axis

2. Median plane-a vertical plane. that divides a body into right and left halves

3. Sagittal plane

• Any plane parallel to the median plane
• Divides the body into right and left portions

4. Frontal plane

• Vertical plane that forms at right angles to the sagittal plane
• Divides the body into anterior and posterior sections
• Synonymous with the term coronal plane

5. Transverse plane

• Horizontal plane that forms at right angles to the sagittal and frontal planes
• Divides the body into upper and lower portions
• Synonymous with the term horizontal plane

C. Relative positions

1. Anterior

• Nearest the abdominal surface and the front of the body
• Synonymous with the term ventral
• In referring to hands and forearms, the terms palmar and Volar are used

2. Posterior

• Back of the body
• Synonymous with the term dorsal

3. Superior

• Upper or higher
• Synonymous with the term cranial (head)

4. Inferior

• Below or lower
• Synonymous with the term caudal (tail)
• In referring to the top of the foot and the sole of the foot. the terms dorsal and plantar are used respectively

5. Medial-near to the median plane

6. Lateral-farther away from the median plane

7. Proximal-near the source or attachment

8. Distal-away from the source or. attachment

9. Superficial-near the surface

10. Deep-away from the surface

11. Afferent-conducting toward a structure

12. Efferent-conducting away from a structure

Movements of the Temporomandibular Joint

• The two movements that occur at this joint are anterior gliding and a hinge-like rotation.
• When the mandible is depressed during opening of the mouth, the head of the mandible and articular disc move anteriorly on the articular surface until the head lies inferior to the articular tubercle.

• As this anterior gliding occurs, the head of the mandible rotates on the inferior surface of the articular disc.
• This permits simple chewing or grinding movements over a small range.

• Movements that are seen in this joint are: depression, elevation, protrusion, retraction and grinding

Histology

Histology is the study of tissues.

A tissue is a group of cells with similar structure and function plus the extracellular substances located between the cells.

There are four basic types of tissues:

- Epitheliums

- Connective tissue

- Muscle tissue

- Nervous tissue

Tongue 
Appears at 4th week.
Musculature derived from mesoderm of occipital somites.  Precursor muscles cells migrate to region of tongue and are innervated by general sensory efferent fibers of CN XII.
Mucosa derived from anterior endoderm lining arches 1-4; accordingly, innervation depends on arch derivation:
              Mucosa of anterior 2/3 of tongue comes from the first arch -> CN V
              Mucosa of posterior 1/3 of tongue comes from third and forth arch -> CN IX, X
Special taste of anterior 2/3 of tongue comes from CN VII.
Special taste of posterior 1/3 of tongue comes from CN X.
Tongue freed from floor of mouth by extensive degeneration of underlying tissue.  Midline frenulum continues to anchor tongue to floor of mouth.

Thyroid Gland

Develops as in growth of mucosal epithelium located in the midline of the tongue (at foramen cecum).  It descends along front of pharyngeal gut, but remains connected to tongue by thyrooglossal duct, which is obliterated later in development.  Thyroid gland descends to a point just caudal to laryngeal cartilages. 

Facial structures (general)

a) medial nasal prominence forms midline of nose, philtrum and primary palate
b) lateral nasal prominence forms alae of nose
c) maxillary prominence forms cheek region and lateral lip
d) clefts can form at inter-prominence fusion lines

Nose

At the time of anterior neural tube closure, mesenchyme around forebrain, frontonasal prominence (FNP), has smooth rounded extended contour.  Nasal placodes (thickening of surface ectoderm to become peripheral neural tissue) develop on frontolateral aspects of FNP.  Mesenchyme swells around nasal placode producing a medial and lateral nasal prominence (nasomedial and nasolateral processes).  These nasal prominences form the nose.

Mouth 

Stomadeum (primitive oral cavity) forms between frontonasal prominence and first pharyngeal arch.  The first pharyngeal arch forms the dorsal maxillary prominence and ventral mandibular prominence.  The maxillary prominence will merge with medial nasal prominences, pushing them closer to cause fusion.  Fused medial nasal prominences will form midline of nose and midline of upper lip (philtrum) and primary palate (first 4 teeth).

Nasolacrimal structures

Maxillary and lateral nasal prominences are separated by deep furrow, the nasolacrimal groove.  Ectoderm in floor of groove forms epithelial cord, which detaches from overlying ectoderm.  The epithelial cord canalizes to form the nasolacrimal duct.  The upper end of the duct widens to form the lacrimal sac.  After detachment of the cord, the maxillary and lateral nasal prominences merge with each other, resulting in the formation of a nasolacrimal duct that runs from the medial corner of the eye to the inferior meatus of the nasal cavity.  
The maxillary prominences enlarge to form the cheeks and maxillae.
The lateral nasal prominences form the alae of the nose.

Secondary (hard) palate

Main part of definitive palate formed by two palatine shelves derived from intraoral bilateral extensions of the maxillary prominences.  These appear at the 6th week.  They are directed obliquely downward on each side of the tongue; they move down when mandible gets bigger.  
At the seventh week, they ascend to attain a horizontal position, then fuse to form the secondary palate.  At the time the palatine shelves fuse, the nasal septum (an outgrowth of median tissue of the frontonasal prominence) grows down and joins the cephalic aspect of the newly formed palate
Anteriorly, shelves fuse with triangular primary palate.  The incisive foramen marks the midline between the primary and secondary palate.

External Ear

The auricle is derived from 6 auricular hillocks (mesenchymal proliferations) along the dorsal aspect of arches 1 (top of ear) and 2 (bottom of ear).  These fuse to form the definitive auricle.  At the mandible grows, the ear is pushed upward and backward from its initial horizontal position on the neck.
The EAM is derived from the 1st pharyngeal arch.  
The eardrum (tympanic membrane) is composed of 3 layers of cells: 1) ectodermal epithelial lining of bottom of EAM; 2) endodermal epithelium lining of tympanic cavity; 3) intermediate layer of connective tissue.
The eardrum is composed of multiple cell layers because it represents the first pharyngeal membrane, and thus lies at the junction of the first pharyngeal pouch and cleft.

Middle Ear

The middle ear consists of an auditory tube (from the 1st pharyngeal pouch, along with tympanic cavity) and the ossicles (from pharyngeal arches 1 and 2 cartilage).  
The first arch cartilage forms the malleus and incus.  The tensor tympani (muscle of the malleus) is derived from the fourth somitomere (associated with the first arch) and is therefore innervated by CN V.
The second arch cartilage forms the stapes.  The stapedius (muscles of the stapes) is derived from the sixth somitomere (associated with the second arch) and is therefore innervated by CN VII.
The ossicles are initially embedded in mesenchyme, but in the 8th month, the mesenchyme degenerates and an endodermal epithelial lining of the tympanic cavity envelops the ossicles and connects them to the wall of the cavity in a mesentery-like fashion.

Inner Ear

The inner ear is derived thickening of surface ectoderm on both sides of the hindbrain (otic placodes).  The placodes invaginate to form otic vesicles (otocytes).  The vesicles then divide into ventral and dorsal components.
The ventral component forms the saccule and cochlear duct.
The dorsal component forms the utricle and semicircular canals and endolymphatic duct.

Cochlear Duct

Derived from an outgrowth of the saccule during the 6th week.  The outgrowth penetrates the surrounding mesenchyme in a spiral fashion.  The surrounding mesenchyme forms the cartilage and undergoes vacuolization.
The scala vestibule and scale tympani form and surround the cochlear duct.  They are filled with periplymp to receive mechanical vibrations of ossicles. The mechanical stimuli activates sensory (ciliary) cells in the cochlear duct.  

Semicircular canals

The utricle is initially three flattened outpocketings, which lose the central core.  From this three semicircular canals are forms, each at 90 degree angles from one another.  Sensory cells arise in the ampulla at one end of each canal, in the utricle and saccule. 

Skeletal Muscle:  1-40 cm long fibres, 10- 60 µm thick, according to myoglobin content there are:

Red fibres: lots of myoglobin, many mitochondriam slow twitching - tire slowly

White fibres:  less myoglobin,  less mitochondria, fast twitching - tire quickly

Intermediate fibres:

mixture of 2 above

Most muscles have all three - in varying ratios

Structure of skeletal muscle:

Light Microscopy:  Many nuclei - 35/mm,  Nuclei are oval - situated peripheral,  Dark and light bands

Electron Microscopy: Two types of myofilaments

Actin

- 5,6 nm

 3 components:

 -actin monomers,  

 -tropomyosin - 7 actin molecules long

- troponin

 actin monomers form 2 threats that spiral

- tropomyosin - lie in the groove of the spiral

- troponin - attach every 40 nm

- one end attach to the Z line

- other end goes to the middle of the sarcomere

- Z line consists of á actinin

Myosin:

- 15 nm

- 1,6 µm long

- The molecule has a head and a tail

- tails are parallel

- heads project in a spiral

- in the middle is a thickening

- thin threats bind the myosin at thickening (M line)

Contraction:

A - band stays the same, I - band, H - bands become narrower

Myosin heads ratchet on the actin molecule

Sarcolemma: 9 nm thick,  invaginate to form T-tubule,

 myofibrils - attach to the sarcolemma

Sarcoplasmic Reticulum:

specialized smooth EPR,  Consists of T-tubules, terminal sisternae and sarcotubules

It is speculated that there are gap junctions between the T-tubule and terminal sisterna

An impulse is carried into the fiber by the T-tubule from where it goes to the rest of the sarcoplasmic reticulum

Connective tissue coverings of the muscle

Endomycium around fibres, perimycium around bundles and epimycium around the whole muscle

Blood vessels and nerves in CT

CT goes over into tendon or aponeurosis which attaches to the periosteum

Nerves:

The axon of a motor neuron branches and ends in motor end plates on the fiber

Specialized striated fibres called spindles (stretch receptors) form sensory receptors in muscles telling the brain how far the muscle has stretched

The Laryngopharynx

• The laryngeal part of the pharynx lies posterior to the larynx.
• It extends from the superior border of the epiglottis to the inferior border of the cricoid cartilage, where it narrows to become continuous with the oesophagus.

• Posteriorly, the laryngopharynx is related to the bodies of C4 to C6 vertebrae.

• Its posterior and lateral walls are formed by the middle and inferior constrictor muscles, with the palatopharyngeus and stylopharyngeus internally.

• The laryngopharynx communicates with the larynx through the aditus or inlet of the larynx.
• The piriform recess is a small, pear-shaped depression of the laryngopharyngeal cavity on each side of the inlet of the larynx.