Disturbances to interarch alignment are

a. Excessive overbite where the incisal edge of the maxillary incisors extend to the cervical third of the mandibular incisors

b. Excessive overjet where the maxillary teeth overjet the mandibular teeth by more than 3mm

c. End-to-end relationship: edge-to edge bite where the anterior teeth meet at there incisal edge with  no overjet or overbite; cusp-to bite where the posterior teeth meet  cusp to cusp with no interdigitation

d. Crossbite where the normal faciolingual relationship of the maxillary to the mandibular teeth is altered for the anterior.teeth. the mandibular  tooth or teeth are facial  rather than lingual to the maxillary teeth for the posterior teeth, normal inercuspaton is not seen

MANDIBULAR SECOND MOLAR

Facial: When compared to the first molar, the second molar crown is shorter both mesiodistally and from the cervix to the occlusal surface. The two well-developed buccal cusps form the occlusal outline. There is no distal cusp as on the first molar. A buccal developmental groove appears between the buccal cusps and passes midway down the buccal surface toward the cervix.

Lingual: The crown is shorter than that of the first molar. The occlusal outline is formed by the mesiolingual and distolingal cusps.

Proximal: The mesial profile resembles that of the first molar. The distal profile is formed by the distobuccal cusp, distal marginal ridge, and the distolingual cusp. Unlike the first molar, there is no distal fifth cusp.

Occlusal: There are four well developed cusps with developmental grooves that meet at a right angle to form the distinctive "+" pattern characteristic of this tooth.

Contact Points; When moving distally from first to third molar, the proximal surfaces become progressively more rounded. The net effect is to displace the contact area cervically and away from the crest of the marginal ridges.

Roots:-The mandibular second molar has two roots that are smaller than those of the first molar. When compared to first molar roots, those of the second tend to be more parallel and to have a more distal inclination.

Dentinogenesis

Dentin formation, known as dentinogenesis, is the first identifiable feature in the crown stage of tooth development. The formation of dentin must always occur before the formation of enamel. The different stages of dentin formation result in different types of dentin: mantle dentin, primary dentin, secondary dentin, and tertiary dentin.

Odontoblasts, the dentin-forming cells, differentiate from cells of the dental papilla. They begin secreting an organic matrix around the area directly adjacent to the inner enamel epithelium, closest to the area of the future cusp of a tooth. The organic matrix contains collagen fibers with large diameters (0.1-0.2 μm in diameter). The odontoblasts begin to move toward the center of the tooth, forming an extension called the odontoblast process. Thus, dentin formation proceeds toward the inside of the tooth. The odontoblast process causes the secretion of hydroxyapatite crystals and mineralization of the matrix. This area of mineralization is known as mantle dentin and is a layer usually about 150 μm thick.

Whereas mantle dentin forms from the preexisting ground substance of the dental papilla, primary dentin forms through a different process. Odontoblasts increase in size, eliminating the availability of any extracellular resources to contribute to an organic matrix for mineralization. Additionally, the larger odontoblasts cause collagen to be secreted in smaller amounts, which results in more tightly arranged, heterogenous nucleation that is used for mineralization. Other materials (such as lipids, phosphoproteins, and phospholipids) are also secreted.

Secondary dentin is formed after root formation is finished and occurs at a much slower rate. It is not formed at a uniform rate along the tooth, but instead forms faster along sections closer to the crown of a tooth. This development continues throughout life and accounts for the smaller areas of pulp found in older individuals. Tertiary dentin, also known as reparative dentin, forms in reaction to stimuli, such as attrition or dental caries.

The dentin in the root of a tooth forms only after the presence of Hertwig's epithelial root sheath (HERS), near the cervical loop of the enamel organ. Root dentin is considered different than dentin found in the crown of the tooth (known as coronal dentin) because of the different orientation of collagen fibers, the decrease of phosphoryn levels, and the less amount of mineralization.

Enamel

Composition: 96% mineral, 4% organic material and water
Crystalline calcium phosphate, hydroxyapatite
Physical characteristics: Hardness compared to mild steel; enamel is brittle
Support from dentin is necessary
Enamel has varies in thickness

Structure of enamel

Ground sections of enamel disclose the information that we have about enamel
Enamel is composed of rods
In the past we used the term prism (do not use)
 

Enamel rod
The rod has a cylinder-like shape and is composed of crystals that run parallel to the longitudinal axis of the rod. At the periphery of the rod the crystals flare laterally.
Interrod region: surrounds each rod; contain more enamel protein (fish scale appearance)
Rod sheath: boundary where crystals of rods meet those of the interrod region at sharp angles (We used to describe that as a keyhole configuration)
Each ameloblast forms one rod and together with adjacent ameloblasts the interrod region Very close to dentin there is no rod structure since the Tomes' processes develop after the first enamel is formed.
Striae of Retzius and cross striations
Incremental lines
Enamel structure is altered along these lines
Cross striations are also a form of incremental lines highlighting the daily secretory activity of ameloblasts

Bands of Hunter and Schreger
Optical phenomenon produced by changes in rod direction

Gnarled enamel
Twisting of rods around each other over the cusps of teeth

Enamel tufts and lamellae
They are like geologic faults
Tufts project from the DE junction, appear branched and contain greater concentrations of enamel protein than enamel
Lamellae extend from the enamel surface
Enamel spindles

Perikymata
Shallow furrows on surface of enamel formed by the striae of Retzius

MAXILLARY SECOND MOLAR

The second molars are often called 12-year molars because they erupt when a child is about 12 years

Facial: The crown is shorter occluso-cervically and narrower mesiodistally whe compared to the first molar. The distobuccal cusp is visibly smaller than the mesiobuccal cusp. The two buccal roots are more nearly parallel. The roots are more parallel; the apex of the mesial root is on line with the with the buccal developmental groove. Mesial and distal roots tend to be about the same length.

Lingual: The distolingual cusp is smaller than the mesiolingual cusp. The Carabelli trait is absent.

Proximal: The crown is shorter than the first molar and the palatal root has less diverence. The roots tend to remain within the crown profile.

Occlusal: The distolingual cusp is smaller on the second than on the first molar. When it is much reduced in size, the crown outline is described as 'heart-shaped.' The Carabelli trait is usually absent. The order of cusp size, largest to smallest, is the same as the first but is more exaggerated: mesiolingual, mesiobuccal, distobuccal, and distolingual.

Contact Points; Height of Curvature: Both mesial and distal contacts tend to be centered buccolingually below the marginal ridges. Since themolars become shorter, moving from first to this molar, the contacts tend to appear more toward the center of the proximal surfaces.

Roots: There are three roots, two buccal and one lingual. The roots are less divergent than the first with their apices usually falling within the crown profile. The buccal roots tend to incline to the distal.

Note: The distolingual cusp is the most variable feature of this tooth. When it is large, the occlusal is somewhat rhomboidal; when reduced in size the crown is described as triangual or 'heart-shaped.' At times, the root may be fused.

Nerve and vascular formation

Frequently, nerves and blood vessels run parallel to each other in the body, and the formation of both usually takes place simultaneously and in a similar fashion. However, this is not the case for nerves and blood vessels around the tooth, because of different rates of development.

Nerve formation

Nerve fibers start to near the tooth during the cap stage of tooth development and grow toward the dental follicle. Once there, the nerves develop around the tooth bud and enter the dental papilla when dentin formation has begun. Nerves never proliferate into the enamel organ

Vascular formation

Blood vessels grow in the dental follicle and enter the dental papilla in the cap stage. Groups of blood vessels form at the entrance of the dental papilla. The number of blood vessels reaches a maximum at the beginning of the crown stage, and the dental papilla eventually forms in the pulp of a tooth. Throughout life, the amount of pulpal tissue in a tooth decreases, which means that the blood supply to the tooth decreases with age. The enamel organ is devoid of blood vessels because of its epithelial origin, and the mineralized tissues of enamel and dentin do not need nutrients from the blood.