NEET MDS Lessons
Dental Anatomy
Amelogenesis and Enamel
Enamel is highly mineralized: 85% hydroxyapatite crystals
Enamel formation is a two-step process
The first step produces partially mineralized enamel: 30% (secretory)
The second step: Influx of minerals, removal of water and organic matrix (maturative)
Again, dentin is the prerequisite of enamel formation (reciprocal induction)
Stratum intermedium: high alkaline phosphatase activity
Differentiation of ameloblasts: Increase in glycogen contents
Formation of the enamel matrix
Enamel proteins, enzymes, metalloproteinases, phosphatases, etc.
Enamel proteins: amelogenins (90%), enamelin, tuftelin, and amelin
Amelogenins: bulk of organic matrix
Tuftelin: secreted at the early stages of amelogenesis (area of the DE junction)
Enamelin: binds to mineral
Amelin
Mineralization of enamel
No matrix vesicles
Immediate formation of crystallites
Intermingling of enamel crystallites with dentin
"Soft" enamel is formed
Histologic changes
Differentiation of inner enamel epithelium cells. They become ameloblasts
Tomes' processes: saw-toothed appearance
Collapse of dental organ
Formation of the reduced enamel epithelium
Hard tissue formation (Amelogenesis )
Enamel formation is called amelogenesis and occurs in the crown stage of tooth development. "Reciprocal induction" governs the relationship between the formation of dentin and enamel; dentin formation must always occur before enamel formation. Generally, enamel formation occurs in two stages: the secretory and maturation stages. Proteins and an organic matrix form a partially mineralized enamel in the secretory stage; the maturation stage completes enamel mineralization.
In the secretory stage, ameloblasts release enamel proteins that contribute to the enamel matrix, which is then partially mineralized by the enzyme alkaline phosphatase. The appearance of this mineralized tissue, which occurs usually around the third or fourth month of pregnancy, marks the first appearance of enamel in the body. Ameloblasts deposit enamel at the location of what become cusps of teeth alongside dentin. Enamel formation then continues outward, away from the center of the tooth.
In the maturation stage, the ameloblasts transport some of the substances used in enamel formation out of the enamel. Thus, the function of ameloblasts changes from enamel production, as occurs in the secretory stage, to transportation of substances. Most of the materials transported by ameloblasts in this stage are proteins used to complete mineralization. The important proteins involved are amelogenins, ameloblastins, enamelins, and tuftelins. By the end of this stage, the enamel has completed its mineralization.
Maxillary Third Permanent Molar
They are the teeth most often congenitally missing
Facial: The crown is usually shorter in both axial and mesiodistal dimensions. Two buccal roots are present, but in most cases they are fused. The mesial buccal cusp is larger than the distal buccal cusp.
Lingual: In most thirds, there is just one large lingual cusp. In some cases there is a poorly developed distolingual cusp and a lingual groove. The lingual root is often fused to the to buccal cusps.
Proximal: The outline of the crown is rounded; it is often described as bulbous in dental literature. Technically, the mesial surface is the only 'proximal' surface. The distal surface does not contact another tooth.
Occlusal: The crown of this tooth is the smallest of the maxillary molars. The outline of the occlusal surface can be described as heart-shaped. The mesial lingual cusp is the largest, the mesial buccal is second in size, and the distal buccal cusp is the smallest.
Root Surface:-The root may have from one to as many as eight divisions. These divisions are usually fused and very often curved distally.
Cementum
Composition
a. Inorganic (50%)—calcium hydroxyapatite crystals.
b. Organic (50%)—water, proteins, and type I collagen.
c. Note: Compared to the other dental tissues, the composition of cementum is most similar to bone; however, unlike bone, cementum is avascular (i.e., no Haversian systems or other vessels are present).
Main function of cementum is to attach PDL fibers to the root surface.
Cementum is generally thickest at the root apex and in interradicular areas of multirooted
Types of cementum
a. Acellular (primary) cementum
(1) A thin layer of cementum that surrounds the root, adjacent to the dentin.
(2) May be covered by a layer of cellular cementum, which most often occurs in the middle and apical root.
(3) It does not contain any cells.
b. Cellular (secondary) cementum
(1) A thicker, less-mineralized layer of cementum that is most prevalent along the apical root and in interradicular (furcal) areas of multirooted teeth.
(2) Contains cementocytes.
(3) Lacunae and canaliculi:
(a) Cementocytes (cementoblasts that become trapped in the extracellular matrix during cementogenesis) are observed in their entrapped spaces, known as lacunae.
(b) The processes of cementocytes extend through narrow channels called canaliculi.
(4) Microscopically, the best way to differentiate between acellular and cellular cementum is the presence of lacunae in cellular cementum.
Tooth eruption Theories
Tooth eruption occurs when the teeth enter the mouth and become visible. Although researchers agree that tooth eruption is a complex process, there is little agreement on the identity of the mechanism that controls eruption. Some commonly held theories that have been disproven over time include: (1) the tooth is pushed upward into the mouth by the growth of the tooth's root, (2) the tooth is pushed upward by the growth of the bone around the tooth, (3) the tooth is pushed upward by vascular pressure, and (4) the tooth is pushed upward by the cushioned hammock. The cushioned hammock theory, first proposed by Harry Sicher, was taught widely from the 1930s to the 1950s. This theory postulated that a ligament below a tooth, which Sicher observed on under a microscope on a histologic slide, was responsible for eruption. Later, the "ligament" Sicher observed was determined to be merely an artifact created in the process of preparing the slide.
The most widely held current theory is that while several forces might be involved in eruption, the periodontal ligaments provide the main impetus for the process. Theorists hypothesize that the periodontal ligaments promote eruption through the shrinking and cross-linking of their collagen fibers and the contraction of their fibroblasts.
Although tooth eruption occurs at different times for different people, a general eruption timeline exists. Typically, humans have 20 primary (baby) teeth and 32 permanent teeth. Tooth eruption has three stages. The first, known as deciduous dentition stage, occurs when only primary teeth are visible. Once the first permanent tooth erupts into the mouth, the teeth are in the mixed (or transitional) dentition. After the last primary tooth falls out of the mouth—a process known as exfoliation—the teeth are in the permanent dentition.
Primary dentition starts on the arrival of the mandibular central incisors, usually at eight months, and lasts until the first permanent molars appear in the mouth, usually at six years. The primary teeth typically erupt in the following order: (1) central incisor, (2) lateral incisor, (3) first molar, (4) canine, and (5) second molar. As a general rule, four teeth erupt for every six months of life, mandibular teeth erupt before maxillary teeth, and teeth erupt sooner in females than males. During primary dentition, the tooth buds of permanent teeth develop below the primary teeth, close to the palate or tongue.
Mixed dentition starts when the first permanent molar appears in the mouth, usually at six years, and lasts until the last primary tooth is lost, usually at eleven or twelve years. Permanent teeth in the maxilla erupt in a different order from permanent teeth on the mandible. Maxillary teeth erupt in the following order: (1) first molar (2) central incisor, (3) lateral incisor, (4) first premolar, (5) second premolar, (6) canine, (7) second molar, and (8) third molar. Mandibular teeth erupt in the following order: (1) first molar (2) central incisor, (3) lateral incisor, (4) canine, (5) first premolar, (6) second premolar, (7) second molar, and (8) third molar. Since there are no premolars in the primary dentition, the primary molars are replaced by permanent premolars. If any primary teeth are lost before permanent teeth are ready to replace them, some posterior teeth may drift forward and cause space to be lost in the mouth. This may cause crowding and/or misplacement once the permanent teeth erupt, which is usually referred to as malocclusion. Orthodontics may be required in such circumstances for an individual to achieve a straight set of teeth.
The permanent dentition begins when the last primary tooth is lost, usually at 11 to 12 years, and lasts for the rest of a person's life or until all of the teeth are lost (edentulism). During this stage, third molars (also called "wisdom teeth") are frequently extracted because of decay, pain or impactions. The main reasons for tooth loss are decay or periodontal disease.
Mixed Dentition Period.
-Begins with the eruption of the first permanent molars distal to the second deciduous molars. These are the first teeth to emerge and they initially articulate in an 'end-on' (one on top of the other) relationship.
-On occasion, the permanent incisors spread out due to spacing. In the older literature, is called by the 'ugly duckling stage.' With the eruption of the permanent canines, the spaces often will close.
-Between ages 6 and 7 years of age there are:
20 deciduous teeth
4 first permanent molars
28 permanent tooth buds in various states of development
MANDIBULAR LATERAL INCISORS
The mandibular incisor is a little wider mesiodistal than the mandibular central incisor, and the crown is slightly longer from the incisal edge to the cervical line.
Facial Surface:-The facial surface is less symmetrical than the facial surface of the mandibular central incisor. The incisal edge slopes upward toward the mesioincisal angle, which is slightly less than 90°. The distoincisal angle is rounded. The mesial border is more nearly straight than the distal border.
Lingual Surface:- The incisal portion of the lingual surface is concave. The cingulum is quite large but blends in smoothly with the rest of the surface.
Root Surface:-The root is single and extremely flattened on its mesial and distal surfaces.
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Maxillary (upper) teeth |
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Primary teeth |
Central |
Lateral |
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First |
Second |
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Initial calcification |
14 wk |
16 wk |
17 wk |
15.5 wk |
19 wk |
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Crown completed |
1.5 mo |
2.5 mo |
9 mo |
6 mo |
11 mo |
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Root completed |
1.5 yr |
2 yr |
3.25 yr |
2.5 yr |
3 yr |
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Mandibular (lower) teeth |
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Initial calcification |
14 wk |
16 wk |
17 wk |
15.5 wk |
18 wk |
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Crown completed |
2.5 mo |
3 mo |
9 mo |
5.5 mo |
10 mo |
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Root completed |
1.5 yr |
1.5 yr |
3.25 yr |
2.5 yr |
3 yr |
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