1. Errors in development. These are usually genetic.

a. Variability of the individual teeth. In general, the teeth most distal in any class are the most variable.

b. Partial or total anodontia. missing teeth in children,

c. Supernumerary teeth.

d. Microdontia

e. Macrodontia

F. Microdontia

2. Errors in skeletal alignment. Malpositioned jaws disrupt normal tooth relationships.

3. Soft tissue problems.

-Ocasionally, the proper eruption of a tooth is prevented by fibrous connective tissue over the crown of the tooth.

-In the mixed dentition, the deciduous second molars have a special importance for the integrity of the permanent dentition. Consider this: The first permanent molars at age six years erupt distal to the second deciduous molars.

-Permanent posterior teeth exhibit physiological mesial drift, the tendency to drift mesially when space is available. If the deciduous second molars are lost prematurely, the first permanent molars drift anteriorly and block out the second premolars.

An incisor diastema may be present. The plural for diastema is diastemata.

-Important: The deciduous anteriors--incisors and canines are narrower than their permanent successors mesiodistally.

-Important: The deciduous molars are wider that their permanent successors mesiodistally.

-This size difference has clinical significance. The difference is called the leeway space.

The leeway space in the lower arch is approximately 3.4 mm.

-The leeway space in the upper arch is approximately 1.8 mm. In normal development, the leeway space is taken up by the mesial migration of the first permanent molars.

The Transition from the Deciduous to the Permanent Dentition.

1. The transition begins with the eruption of the four first permanent molars, and replacement of the lower deciduous central incisors by the permanent lower central incisors.

2. Complete resorption of the deciduous tooth roots permits exfoliation of that tooth and replacement by the permanent (successional) teeth

3. The mixed dentition exists from approximately age 6 years to approximately age 12 years. In contrast, the intact deciduous dentition is functional from age 2 - 2 /2 years of age to 6 years of age.

4. The enamel organ of each permanent anterior tooth is connected to the oral epithelium via a fibrous cord, the gubernaculum. The foramina through which it passes can be seen in youthful skulls

The deciduous second molars are particularly important. It is imperative that the deciduous second molars be preserved until their normal time of exfoliation. This prevent mesial migration of the first permanent molars.

Use a space maintainer in the event that a second deciduous molar is lost prematurely

Bell stage

The bell stage is known for the histodifferentiation and morphodifferentiation that takes place. The dental organ is bell-shaped during this stage, and the majority of its cells are called stellate reticulum because of their star-shaped appearance. Cells on the periphery of the enamel organ separate into three important layers. Cuboidal cells on the periphery of the dental organ are known as outer enamel epithelium.The cells of the enamel organ adjacent to the dental papilla are known as inner enamel epithelium. The cells between the inner enamel epithelium and the stellate reticulum form a layer known as the stratum intermedium. The rim of the dental organ where the outer and inner enamel epithelium join is called the cervical loop

Other events occur during the bell stage. The dental lamina disintegrates, leaving the developing teeth completely separated from the epithelium of the oral cavity; the two will not join again until the final eruption of the tooth into the mouth

The crown of the tooth, which is influenced by the shape of the internal enamel epithelium, also takes shape during this stage. Throughout the mouth, all teeth undergo this same process; it is still uncertain why teeth form various crown shapes—for instance, incisors versus canines. There are two dominant hypotheses. The "field model" proposes there are components for each type of tooth shape found in the ectomesenchyme during tooth development. The components for particular types of teeth, such as incisors, are localized in one area and dissipate rapidly in different parts of the mouth. Thus, for example, the "incisor field" has factors that develop teeth into incisor shape, and this field is concentrated in the central incisor area, but decreases rapidly in the canine area. The other dominant hypothesis, the "clone model", proposes that the epithelium programs a group of ectomesenchymal cells to generate teeth of particular shapes. This group of cells, called a clone, coaxes the dental lamina into tooth development, causing a tooth bud to form. Growth of the dental lamina continues in an area called the "progress zone". Once the progress zone travels a certain distance from the first tooth bud, a second tooth bud will start to develop. These two models are not necessarily mutually exclusive, nor does widely accepted dental science consider them to be so: it is postulated that both models influence tooth development at different times.Other structures that may appear in a developing tooth in this stage are enamel knots, enamel cords, and enamel niche.

AGE CHANGES

Progressive apical migration of the dentogingival junction.
Toothbrush abrasion of the area can expose dentin that can cause root caries and tooth mobility.

Histology of the alveolar bone

Near the end of the 2nd month of fetal life, mandible and maxilla form a groove that is opened toward the surface of the oral cavity.
As tooth germs start to develop, bony septa form gradually. The alveolar process starts developing strictly during tooth eruption.

The alveolar process is the bone that contains the sockets (alveoli) for the teeth and consists of

a) outer cortical plates
b) a central spongiosa and
c) bone lining the alveolus (bundle bone)

The alveolar crest is found 1.5-2.0 mm below the level of the CEJ.
If you draw a line connecting the CE junctions of adjacent teeth, this line should be parallel to the alveolar crest. If the line is not parallel, then there is high probability of periodontal disease.

Bundle Bone

The bundle bone provides attachment to the periodontal ligament fibers. It is perforated by many foramina that transmit nerves and vessels (cribiform plate). Embedded within the bone are the extrinsic fiber bundles of the PDL mineralized only at the periphery. Radiographically, the bundle bone is the lamina dura. The lining of the alveolus is fairly smooth in the young but rougher in the adults.

Clinical considerations

Resorption and regeneration of alveolar bone
This process can occur during orthodontic movement of teeth. Bone is resorbed on the side of pressure and opposed on the site of tension.

Osteoporosis
Osteoporosis of the alveolar process can be caused by inactivity of tooth that does not have an antagonist

Histology of the Periodontal Ligament (PDL)

Embryogenesis of the periodontal ligament
The PDL forms from the dental follicle shortly after root development begins
The periodontal ligament is characterized by connective tissue. The thinnest portion is at the middle third of the root. Its width decreases with age. It is a tissue with a high turnover rate.

FUNCTIONS OF PERIODONTIUM

Tooth support
Shock absorber
Sensory (vibrations appreciated in the middle ear/reflex jaw opening)

The following cells can be identified in the periodontal ligament:
a) Osteoblasts and osteoclasts b) Fibroblasts,  c) Epithelial cells
 

Rests of Malassez
d) Macrophages
e) Undifferentiated cells
f) Cementoblasts and cementoclasts (only in pathologic conditions)
The following types of fibers are found in the PDL
-Collagen fibers: groups of fibers
-Oxytalan fibers: variant of elastic fibers, perpendicular to teeth, adjacent to capillaries
-Eluanin: variant of elastic fibers
Ground substance

PERIODONTAL LIGAMENT FIBERS

Principal fibers
These fibers connect the cementum to the alveolar crest. These are:

a. Alveolar crest group: below CE junction, downward, outward
b. Horizontal group: apical to ACG, right angle
c. Oblique group: numerous, coronally to bone, oblique direction
d. Apical group: around the apex, base of socket
e. Interradicular group: multirooted teeth

Gingival ligament fibers
This group is not strictly related to periodontium. These fibers are:

a. Dentogingival: numerous, cervical cementum to f/a gingiva
b. Alveologingival: bone to f/a gingiva
c. Circular: around neck of teeth, free gingiva
d. Dentoperiosteal: cementum to alv. process or vestibule (muscle)
 e. Transseptal: cementum between adjacent teeth, over the alveolar crest
 

Blood supply of the PDL
The PDL gets its blood supply from perforating arteries (from the cribriform plate of the bundle bone). The small capillaries derive from the superior & inferior alveolar arteries. The blood supply is rich because the PDL has a very high turnover as a tissue. The posterior supply is more prominent than the anterior. The mandibular is more prominent than the maxillary.

Nerve supply
The nerve supply originates from the inferior or the superior alveolar nerves. The fibers enter from the apical region and lateral socket walls. The apical region contains more nerve endings (except Upper Incisors)

Dentogingival junction

This area contains the gingival sulcus. The normal depth of the sulcus is 0.5 to 3.0 mm (mean: 1.8 mm). Depth > 3.0 mm is considered pathologic. The sulcus contains the crevicular fluid
 

 
The dentogingival junction is surfaced by:
1) Gingival epithelium: stratified squamous keratinized epithelium 2) Sulcular epithelium: stratified squamous non-keratinized epithelium The lack of keratinization is probably due to inflammation and due to high turnover of this epithelium.
3) Junctional epithelium: flattened epithelial cells with widened intercellular spaces. In the epithelium one identifies neutrophils and monocytes.
Connective tissue
The connective tissue of the dentogingival junction contains inflammatory cells, especially polymorphonuclear neutrophils. These cells migrate to the sulcular and junctional epithelium.
The connective tissue that supports the sulcular epithelium is also structurally and functionally different than the connective tissue that supports the junctional epithelium.

Histology of the Col (=depression)

The col is found in the interdental gingiva. It is surfaced by epithelium that is identical to junctional epithelium. It is an important area because of the accumulation of bacteria, food debris and plaque that can cause periodontal disease.
Blood supply: periosteal vessels
Nerve supply: periodontal nerve fibers, infraorbital, palatine, lingual, mental, buccal

TOOTH MORPHOLOGY

Descriptive anatomy

• Median sagittal plane: the imaginary plane in the center that divides right from left.
• Median line: an imaginary line on that plane that bisects the dental arch at the center.
• Mesial: toward the center (median) line of the dental arch.
• Distal: away from the center (median) line of the dental arch.
• Occlusal plane: A plane formed by the cusps of the teeth. It is often curved, as in a cylinder. We will speak often of the occlusal surface of a tooth.
• Proximal: the surface of a tooth that is toward another tooth in the arch.
• Mesial surface: toward the midline.
• Distal surface: away from the midline.
• Facial: toward the cheeks or lips.
• Labial: facial surface of anterior teeth (toward the lips).
• Buccal: facial surfaceof anterior teeth (toward the cheeks).
• Lingual: toward the tongue.
• Occlusal: the biting surface; that surface that articulates with an antagonist tooth in an opposing arch.
• Incisal: cutting edge of anterior teeth.
• Apical: toward the apex, the tip of the root.