MAXILLARY CUSPIDS (CANINE)

The maxillary cuspid is usually the longest tooth in either jaw. canines are considered the corner stones of the dental arch They are the only teeth in the dentition with a single cusp.

Facial Surface:- The facial surface of the crown differs considerably from that of the maxillary central or lateral incisors. In that the incisal edges of the central and lateral incisor are nearly straight, the cuspid has a definite point, or cusp.  There are two cutting edges, the mesioincisal and the distoincisal. The distoincisal cutting edge is the longer of the two. The developmental grooves prominent on the facial surface  extending two-thirds of the distance from the tip of the cusp to the cervical line.  The distal cusp ridge is longer than the mesial cusp ridge

Lingual Surface:  Distinct mesial and distal marginal ridges, a well-devloped cingulum, and the cusp ridges form the boundries of the lingual surface. The prominent lingual ridge extends from the cusp tip to the cingulum, dividing the lingual surface into mesial and distal fossae.

Proximal: The mesial and distal aspects present a triangular outline. They resemble the incisors, but are more robust--especially in the cingulum region

Incisal: The asymmetry of this tooth is readily apparent from this aspect. It usually thicker labiolingually than it is mesiodistally. The tip of the cusp is displaced labially and mesial to the central long axis of this tooth.

Root Surface:-The root is single and is the longest root in the arch. It is usually twice the length of the crown.

AGE CHANGES

Progressive apical migration of the dentogingival junction.
Toothbrush abrasion of the area can expose dentin that can cause root caries and tooth mobility.

Histology of the alveolar bone

Near the end of the 2nd month of fetal life, mandible and maxilla form a groove that is opened toward the surface of the oral cavity.
As tooth germs start to develop, bony septa form gradually. The alveolar process starts developing strictly during tooth eruption.

The alveolar process is the bone that contains the sockets (alveoli) for the teeth and consists of

a) outer cortical plates
b) a central spongiosa and
c) bone lining the alveolus (bundle bone)

The alveolar crest is found 1.5-2.0 mm below the level of the CEJ.
If you draw a line connecting the CE junctions of adjacent teeth, this line should be parallel to the alveolar crest. If the line is not parallel, then there is high probability of periodontal disease.

Bundle Bone

The bundle bone provides attachment to the periodontal ligament fibers. It is perforated by many foramina that transmit nerves and vessels (cribiform plate). Embedded within the bone are the extrinsic fiber bundles of the PDL mineralized only at the periphery. Radiographically, the bundle bone is the lamina dura. The lining of the alveolus is fairly smooth in the young but rougher in the adults.

Clinical considerations

Resorption and regeneration of alveolar bone
This process can occur during orthodontic movement of teeth. Bone is resorbed on the side of pressure and opposed on the site of tension.

Osteoporosis
Osteoporosis of the alveolar process can be caused by inactivity of tooth that does not have an antagonist

Permanent teeth

1. The permanent teeth begin formation between birth and 3 years of age (except for the third molars)

2. The crowns of permanent teeth are completed between 4 and 8 years of age, at approximately one- half the age of eruption

The sequence for permanent development

Maxillary                     

First molar → Central incisor → Lateral incisor → First premotar → Second pmmolar  → Canine → Second molar → Third molar

Mandibular

First molar → Central incisor → Lateral incisor → Canine → First premolar → Second premolar → Second molar → Third molar

Permanent teeth emerge into the oral cavity as

                                      Maxillary                       Mandibular

Central incisor               7-8 years                        6-7 years

Lateral incisor                8-9 years                        7-8 years

Canine                           11-12 years                    9-10 years

First premolar                10-Il years                      10-12 years

Second premolar            10-12 years                  11-12 years

First molar                       6-7 years                      6-7 years

Second molar                 12-13 years                    11-13 years

Third molar                      17-21 years                    17-21 years

The roots of the permanent teeth are completed between 10 and 16 years of age, 2 to 3 years after eruption

Structure

There are 3 pairs

 The functional unit is the adenomere.

The adenomere consists of secreting units and an intercalated duct, which opens, in a striated duct.

An secreting unit can be:

- mucous secreting

- serous secreting

THE SECRETING UNIT

THE CELLS

Serous cells

(seromucus cells=secrete also polysaccharides), They have all the features of a cell specialized for the synthesis, storage, and secretion of protein
 Pyramidal, Nuclei are rounded and more centrally placed,  In the basal 1/3 there is an accumulation of Granular EPR,  In the apex there are proteinaceous secretory granules,  Cells stain well with H & E (red),  Between cells are intercellular secretory capillaries

Rough endoplasmic reticulum (ribosomal sites-->cisternae)
Prominent Golgi-->carbohydrate moieties are added
Secretory granules-->exocytosis
The secretory process is continuous but cyclic
There are complex foldings of cytoplasmic membrane
The junctional complex consists of: 1) tight junctions (zonula occludens)-->fusion of outer cell layer, 2) intermediate junction (zonula adherens)-->intercellular communication, 3)desmosomes-->firm adhesion

Mucus cells

Pyramidal,  Nuclei are flattened and near the base,  Have big clear secretory granules

Cells do not stain well with H & E (white)

Production, storage, and secretion of proteinaceous material; smaller enzymatic component
-more carbohydrates-->mucins=more prominent Golgi
-less prominent (conspicuous) rough endoplasmic reticulum, mitochondria
-less interdigitations
 

Myoepithelial cells

Star-shaped, Centrally located nucleus, Long cytoplasmic arms - bound to the secretory cells by desmosomes, Have fibrils like smooth muscle, Squeeze the secretory cell

One, two or even three myoepithelial cells in each salivary and piece body, four to eight processes
Desmosomes between myoepithelial cells and secretory cells myofilaments frequently aggregated to form dark bodies along the course of the process. The myoepithelial cells of the intercalated ducts are more spindled-shaped and fewer processes
Ultrastructure very similar to that of smooth muscle cells (myofilaments, desmosomal attachments)
 

Functions of myoepithelial cells
-Support secretory cells
-Contract and widen the diameter of the intercalated ducts
-Contraction may aid in the rupture of acinar cells of epithelial origin

Ductal system

Three classes of ducts:
Intercalated ducts

They have small diameter; lined by small cuboidal cells; nucleus located in the center. They have a well-developed RER, Golgi apparatus, occasionally secretory granules, few microvilli. Myoepithelial cells are also present. Intercalated ducts are prominent in salivary glands having a watery secretion (parotid).
Striated ducts

They have columnar cells, a centrally located nucleus, eosinophilic cytoplasm. Prominenty striations that refer to indentations of the cytoplasmic membrane with many mitochondria present between the folds. Some RER and some Golgi. The cells have short microvilli.
The cells of the striated ducts modify the secretion (hypotonic solution=low sodium and chloride and high potassium). There is also presence of few basal cells.
Terminal excretory ducts

Near the striated ducts they have the same histology as the striated ducts. As the duct reaches the oral mucosa the lining becomes stratified. In the terminal ducts one can find goblet cells, basal cells, clear cells. The terminal ducts alter the electrolyte concentration and add mucoid substance.

Connective tissue
Presence of fibroblasts, inflammatory cells, mast cells, adipose cells
Extracellular matrix (glycoproteins and proteoglycans)
Collagen and oxytalan fibers
 

 Nerve supply
The innervation of salivary glands is very complicated. There is no direct inhibitory innervation. There are parasympathetic and sympathetic impulses, the parasympathetic are more prevalent.
The parasympathetic impulses may occur in isolation, evoke most of the fluid to be excreted, cause exocytosis, induce contraction of myoepithelial cells (sympathetic too) and cause vasodialtion. There are two types of innervation: epilemmal and hypolemmal. There are beta-adrenergic receptors that induce protein secretion and L-adrenergic and cholinergic receptors that induce water and electrolyte secretion.

Hormones can influence the function of the salivary glands. They modify the salivary content but cannot initiate salivary flow.

Age changes

Fibrosis and fatty degenerative changes
Presence of oncocytes (eosinophilic cells containing many mitochondria)

Clinical considerations

Role of drugs, systemic disorders, bacterial or viral infections, therapeutic radiation, obstruction, formation of plaque and calculus.

    - Rich capillary networks surround the adenomeres.

MANDIBULAR CUSPIDS

Mandibular canines are those lower teeth that articulate with the mesial aspect of the upper canine.

Facial: The mandibular canine is noticeably narrower mesidistally than the upper, but the root may be as long as that of the upper canine. In an individual person,the lower canine is often shorter than that of the upper canine. The mandibular canine is wider mesiodistally than either lower incisor. A distinctive feature is the nearly straight outline of the mesial aspect of the crown and root. When the tooth is unworn, the mesial cusp ridge appears as a sort of 'shoulder' on the tooth. The mesial cusp ridge is much shorter than the distal cusp ridge.

Lingual: The marginal ridges and cingulum are less prominent than those of the maxillary canine. The lingual surface is smooth and regular. The lingual ridge, if present, is usually rather subtle in its expression.

Proximal: The mesial and distal aspects present a triangular outline. The cingulum as noted is less well developed. When the crown and root are viewed from the proximal, this tooth uniquely presents a crescent-like profile similar to a cashew nut.

Incisal: The mesiodistal dimension is clearly less than the labiolingual dimension. The mesial and distal 'halves' of the tooth are more identical than the upper canine from this perspective. In the mandibular canine, the unworn incisal edge is on the line through the long axis of this tooth.

Tooth development is commonly divided into the following stages: the bud stage, the cap, the bell, and finally maturation. The staging of tooth development is an attempt to categorize changes that take place along a continuum; frequently it is difficult to decide what stage should be assigned to a particular developing tooth. This determination is further complicated by the varying appearance of different histological sections of the same developing tooth, which can appear to be different stages.

Bud stage

The bud stage is characterized by the appearance of a tooth bud without a clear arrangement of cells. The stage technically begins once epithelial cells proliferate into the ectomesenchyme of the jaw. The tooth bud itself is the group of cells at the end of the dental lamina.