Bell stage

The bell stage is known for the histodifferentiation and morphodifferentiation that takes place. The dental organ is bell-shaped during this stage, and the majority of its cells are called stellate reticulum because of their star-shaped appearance. Cells on the periphery of the enamel organ separate into three important layers. Cuboidal cells on the periphery of the dental organ are known as outer enamel epithelium.The cells of the enamel organ adjacent to the dental papilla are known as inner enamel epithelium. The cells between the inner enamel epithelium and the stellate reticulum form a layer known as the stratum intermedium. The rim of the dental organ where the outer and inner enamel epithelium join is called the cervical loop

Other events occur during the bell stage. The dental lamina disintegrates, leaving the developing teeth completely separated from the epithelium of the oral cavity; the two will not join again until the final eruption of the tooth into the mouth

The crown of the tooth, which is influenced by the shape of the internal enamel epithelium, also takes shape during this stage. Throughout the mouth, all teeth undergo this same process; it is still uncertain why teeth form various crown shapes—for instance, incisors versus canines. There are two dominant hypotheses. The "field model" proposes there are components for each type of tooth shape found in the ectomesenchyme during tooth development. The components for particular types of teeth, such as incisors, are localized in one area and dissipate rapidly in different parts of the mouth. Thus, for example, the "incisor field" has factors that develop teeth into incisor shape, and this field is concentrated in the central incisor area, but decreases rapidly in the canine area. The other dominant hypothesis, the "clone model", proposes that the epithelium programs a group of ectomesenchymal cells to generate teeth of particular shapes. This group of cells, called a clone, coaxes the dental lamina into tooth development, causing a tooth bud to form. Growth of the dental lamina continues in an area called the "progress zone". Once the progress zone travels a certain distance from the first tooth bud, a second tooth bud will start to develop. These two models are not necessarily mutually exclusive, nor does widely accepted dental science consider them to be so: it is postulated that both models influence tooth development at different times.Other structures that may appear in a developing tooth in this stage are enamel knots, enamel cords, and enamel niche.

The periodontium consists of tissues supporting and investing the tooth and includes cementum, the periodontal ligament (PDL), and alveolar bone.

Parts of the gingiva adjacent to the tooth also give minor support, although the gingiva is Not considered to be part of the periodontium in many texts. For our purposes here, the groups Of gingival fibers related to tooth investment are discussed in this section.

Abnormalities

There are a number of tooth abnormalities relating to development.

Anodontia is a complete lack of tooth development, and hypodontia is a lack of some tooth development. Anodontia is rare, most often occurring in a condition called hipohidrotic ectodermal dysplasia, while hypodontia is one of the most common developmental abnormalities, affecting 3.5–8.0% of the population (not including third molars). The absence of third molars is very common, occurring in 20–23% of the population, followed in prevalence by the second premolar and lateral incisor. Hypodontia is often associated with the absence of a dental lamina, which is vulnerable to environmental forces, such as infection and chemotherapy medications, and is also associated with many syndromes, such as Down syndrome and Crouzon syndrome.

Hyperdontia is the development of extraneous teeth. It occurs in 1–3% of Caucasians and is more frequent in Asians. About 86% of these cases involve a single extra tooth in the mouth, most commonly found in the maxilla, where the incisors are located. Hyperdontia is believed to be associated with an excess of dental lamina.

Dilaceration is an abnormal bend found on a tooth, and is nearly always associated with trauma that moves the developing tooth bud. As a tooth is forming, a force can move the tooth from its original position, leaving the rest of the tooth to form at an abnormal angle. Cysts or tumors adjacent to a tooth bud are forces known to cause dilaceration, as are primary (baby) teeth pushed upward by trauma into the gingiva where it moves the tooth bud of the permanent tooth.

Regional odontodysplasia is rare, but is most likely to occur in the maxilla and anterior teeth. The cause is unknown; a number of causes have been postulated, including a disturbance in the neural crest cells, infection, radiation therapy, and a decrease in vascular supply (the most widely held hypothesis).Teeth affected by regional odontodysplasia never erupt into the mouth, have small crowns, are yellow-brown, and have irregular shapes. The appearance of these teeth in radiographs is translucent and "wispy," resulting in the nickname "ghost teeth"

ARTICULAR SURFACES COVERED BY FIBROUS TISSUE
TMJ is an exception form other synovial joints. Two other joints, the acromio- and sternoclavicular joints are similar to the TMJ. Mandible & clavicle derive from intramembranous ossificiation.

Histologic

1. Fibrous layer: collagen type I, avascular (self-contained and replicating)
2. Proliferating zone that formes condylar cartilage
3. Condylar cartilage is fibrocartilage that does not play role in articulation nor has formal function
4. Capsule: dense collagenous tissue (includes the articular eminence)
5. Synovial membrane: lines capsule (does not cover disk except posterior region); contains folds (increase in pathologic conditions) and villi
   Two layers: a cellular intima (synovial cells in fiber-free matrix) and a vascular subintima
   Synovial cells: A (macrophage-like) syntesize hyaluronate
   B (fibroblast-like) add protein in the fluid
   Synovial fluid: plasma with mucin and proteins, cells
   Liquid environment: lubrication, ?nutrition
6. Disk: separates the cavity into two comprartments, type I collagen
   anterior and posterior portions
   anetiorly it divides into two lamellae one towards the capsule, the other towards the condyle
   vascular in the preiphery, avascular in the center
7. Ligaments: nonelastic collagenous structures. One ligament worth mentioning is the lateral or temporomandibular ligament. Also there are the spheno- and stylomandibular with debatable functional role.

Innervations
 

Maxillary Second Deciduous Molar.

-The notation is A or J.

-It looks like a first permanent molar

-There are three roots.

-Usually it has four well developed cusps.

-It is somwhat rhomboidal in outline.

-They often have the Carabelli trait.

- the shape the maxillary first permanent molar strongly resembles that of the adjacent deciduous second molar.

Mandibular Second Deciduous Molar.

-This tooth resembles the lower first permanent molar that is d

istal to it in the dental arch.

-There are two roots and five cusps. The three buccal cusps are all about the same size. This is in contrast to the lower first molar where the 'distal' cusp is smaller that the mesiobuccal and distobuccal cusps.

-The distal of the three buccal cusps may be shifted of onto the distal marginal ridge.  

NOTE

-Upper molars have three roots, lowers have two roots.

-Upper and lower second deciduous molars resemble first permanent molars in the same quadrant.

-Upper first deciduous molars vaguely resemble upper premolars. -Lower first deciduous molars are odd and unique unto themselves.

-First deciduous molars (upper and lower) have a prominent bulge of enamel on the buccal at the mesial. These help in determining right and left.