NEET MDS Lessons
Dental Anatomy
Cementum & Cementogenesis
Cementum formation is called cementogenesis and occurs late in the development of teeth. Cementoblasts are the cells responsible for cementogenesis. Two types of cementum form: cellular and acellular.
Acellular cementum forms first. The cementoblasts differentiate from follicular cells, which can only reach the surface of the tooth's root once Hertwig's Epithelial Root Sheath (HERS) has begun to deteriorate. The cementoblasts secrete fine collagen fibrils along the root surface at right angles before migrating away from the tooth. As the cementoblasts move, more collagen is deposited to lengthen and thicken the bundles of fibers. Noncollagenous proteins, such as bone sialoprotein and osteocalcin, are also secreted. Acellular cementum contains a secreted matrix of proteins and fibers. As mineralization takes place, the cementoblasts move away from the cementum, and the fibers left along the surface eventually join the forming periodontal ligmaments.
Cellular cementum develops after most of the tooth formation is complete and after the tooth occludes (in contact) with a tooth in the opposite arch. This type of cementum forms around the fiber bundles of the periodontal ligaments. The cementoblasts forming cellular cementum become trapped in the cementum they produce.
The origin of the formative cementoblasts is believed to be different for cellular cementum and acellular cementum. One of the major current hypotheses is that cells producing cellular cementum migrate from the adjacent area of bone, while cells producing acellular cementum arise from the dental follicle. Nonetheless, it is known that cellular cementum is usually not found in teeth with one root. In premolars and molars, cellular cementum is found only in the part of the root closest to the apex and in interradicular areas between multiple roots.
CEMENTUM vs. BONE
Cementum simulates bone
1) Organic fibrous framework, ground substance, crystal type, development
2) Lacunae
3) Canaliculi
4) Cellular components
5) Incremental lines (also known as "resting" lines; they are produced by continuous but phasic, deposition of cementum)
Differences between cementum and bone
1) Cementum is not vascularized
2) Cementum has minor ability to remodel
3) Cementum is more resistant to resorption compared to bone
4) Cementum lacks neural component
5) Cementum contains a unique proteoglycan interfibrillar substance
6) 70% of bone is made by inorganic salts (cementum only 46%)
Relation of Cementum to Enamel at the Cementoenamel Junction (CEJ)
"OMG rule"
In 60% of the teeth cementum Overlaps enamel
In 30% of the teeth cementum just Meets enamel
In 10% of the teeth there is a small Gap between cementum and enamel
Cementum
Composition
a. Inorganic (50%)—calcium hydroxyapatite crystals.
b. Organic (50%)—water, proteins, and type I collagen.
c. Note: Compared to the other dental tissues, the composition of cementum is most similar to bone; however, unlike bone, cementum is avascular (i.e., no Haversian systems or other vessels are present).
Main function of cementum is to attach PDL fibers to the root surface.
Cementum is generally thickest at the root apex and in interradicular areas of multirooted
Types of cementum
a. Acellular (primary) cementum
(1) A thin layer of cementum that surrounds the root, adjacent to the dentin.
(2) May be covered by a layer of cellular cementum, which most often occurs in the middle and apical root.
(3) It does not contain any cells.
b. Cellular (secondary) cementum
(1) A thicker, less-mineralized layer of cementum that is most prevalent along the apical root and in interradicular (furcal) areas of multirooted teeth.
(2) Contains cementocytes.
(3) Lacunae and canaliculi:
(a) Cementocytes (cementoblasts that become trapped in the extracellular matrix during cementogenesis) are observed in their entrapped spaces, known as lacunae.
(b) The processes of cementocytes extend through narrow channels called canaliculi.
(4) Microscopically, the best way to differentiate between acellular and cellular cementum is the presence of lacunae in cellular cementum.
Histology of the Pulp
PARTICIPATING CELLS
1. Odontoblasts (body and process)
Most distinctive cells of the pulp
Single layer
The cells are columnar in the coronal portion, cuboidal in the middle portion, flat in the apical portion
Individual odontoblasts communicate with each other via junctions. The number of odontoblasts corresponds to the number of dentinal tubules.
The lifespan of an odontoblast equals the one of a vital tooth.
The morphology of the odontoblasts reflects their functional activity.
(There are three stages that reflect the functional activity of a cell: active, transitional and resting)
The odontoblastic process
2. Fibroblasts
Most numerous cells
Produce collagen fibers and ground substance
Ground substance consists of: proteoglycans and glycoproteins
Again, active and resting cells
Fibroblasts have also capability to degrade collagen
3. Undifferentiated mesenchymal cells A pool of cells from which connective tissue cells can derive.
They are reduced with age.
4. Endothelial cells, Schwann cells, pericytes and immunocompetent cells
MATRIX
It is composed of fibers and ground substance
55% of the fibers are Type I collagen. 45% of the fibers are Type III collagen.
The ground substance is gelatinous in the coronal aspect and more fibrous in the apical.
VASCULARITY
Superior and inferior alveolar arteries that derive from the external carotids
Afferent side of the circulation: arterioles
Efferent side of the circulation: venules
Lymphatics
Small, blind, thin-walled vessels in the coronal region of the pulp and exit via one or two larger vessels.
MANDIBULAR SECOND BICUSPID
Facial: From this aspect, the tooth somewhat resembles the first, but the buccal cusp is less pronounced. The tooth is larger than the first.
Lingual: Two significant variations are seen in this view. The most common is the three-cusp form which has two lingual cusps. The mesial of those is the larger of the two. The other form is the two-cusp for with a single lingual cusp. In that variant, the lingual cusp tip is shifted to the mesial.
Proximal: The buccal cusp is shorter than the first. The lingual cusp (or cusps) are much better developed than the first and give the lingual a full, well-developed profile.
Occlusal: The two or three cusp versions become clearly evident. In the three-cusp version, the developmental grooves present a distinctive 'Y' shape and have a central pit. In the two cusp version, a single developmental groove crosses the transverse ridge from mesial to distal
Contact Points; Height of Curvature: From the facial, the mesial contact is more occlusal than the distal contact.The distal marginal ridge is lower than the mesial marginal ridge
Root Surface:-The root of the tooth is single, that is usually larger than that of the first premolar
the lower second premolar is larger than the first, while the upper first premolar is just slightly larger than the upper second
There may be one or two lingual cusps
|
|
Maxillary (upper) teeth |
||||
|
Primary teeth |
Central |
Lateral |
|
First |
Second |
|
Initial calcification |
14 wk |
16 wk |
17 wk |
15.5 wk |
19 wk |
|
Crown completed |
1.5 mo |
2.5 mo |
9 mo |
6 mo |
11 mo |
|
Root completed |
1.5 yr |
2 yr |
3.25 yr |
2.5 yr |
3 yr |
|
|
Mandibular (lower) teeth |
||||
|
Initial calcification |
14 wk |
16 wk |
17 wk |
15.5 wk |
18 wk |
|
Crown completed |
2.5 mo |
3 mo |
9 mo |
5.5 mo |
10 mo |
|
Root completed |
1.5 yr |
1.5 yr |
3.25 yr |
2.5 yr |
3 yr |
|
|
|
|
|
|
|
AGE CHANGES
Progressive apical migration of the dentogingival junction.
Toothbrush abrasion of the area can expose dentin that can cause root caries and tooth mobility.
Histology of the alveolar bone
Near the end of the 2nd month of fetal life, mandible and maxilla form a groove that is opened toward the surface of the oral cavity.
As tooth germs start to develop, bony septa form gradually. The alveolar process starts developing strictly during tooth eruption.
The alveolar process is the bone that contains the sockets (alveoli) for the teeth and consists of
a) outer cortical plates
b) a central spongiosa and
c) bone lining the alveolus (bundle bone)
The alveolar crest is found 1.5-2.0 mm below the level of the CEJ.
If you draw a line connecting the CE junctions of adjacent teeth, this line should be parallel to the alveolar crest. If the line is not parallel, then there is high probability of periodontal disease.
Bundle Bone
The bundle bone provides attachment to the periodontal ligament fibers. It is perforated by many foramina that transmit nerves and vessels (cribiform plate). Embedded within the bone are the extrinsic fiber bundles of the PDL mineralized only at the periphery. Radiographically, the bundle bone is the lamina dura. The lining of the alveolus is fairly smooth in the young but rougher in the adults.
Clinical considerations
Resorption and regeneration of alveolar bone
This process can occur during orthodontic movement of teeth. Bone is resorbed on the side of pressure and opposed on the site of tension.
Osteoporosis
Osteoporosis of the alveolar process can be caused by inactivity of tooth that does not have an antagonist