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Oral Pathology

  • Café au Lait Spots:

    • "Coast of California": Associated with Neurofibromatosis (Type 1).

    • "Coast of Maine": Associated with Fibrous Dysplasia.

  • Carpet Tack Lesions: Characteristic of Discoid Lupus Erythematosus.

  • Cerebriform Tongue: Seen in Pemphigus Vegetans.

  • Charcot's Triad: Seen in Multiple Sclerosis, characterized by:

    • Intention tremor

    • Nystagmus

    • Dysarthria

  • Chipmunk Facies: Seen in Thalassemia.

  • Chvostek's Sign: Indicative of Hypoparathyroidism (facial muscle twitching upon tapping the facial nerve).

  • Buffalo Hump: A characteristic clinical sign of Cushing's Syndrome (fat pad on the upper back).

  • Actinomycosis (Sulfur Granules):

    • Yellow sulfur granules: Are actually bacterial colonies.

    • Histopathology: Colonies appear "cotton wool" shaped. (Note: "Cotton wool appearance" is seen radiographically in Paget's disease).

  • Tuberculosis (TB):

    • Diagnosis (Gold Standard): Presence of acid-fast bacilli in sputum.

    • Staining Method: Ziehl-Neelsen staining method is used to identify acid-fast bacilli.

    • Scrofula: TB of cervical lymph nodes.

    • Lupus Vulgaris: TB of skin.

  • Tongue & Gingival Appearance in Systemic Conditions:

    • Strawberry tongue and Raspberry tongue: Seen in stomatitis of Scarlet Fever.

    • Strawberry Gingivitis: Seen in Wegener's Granulomatosis.

Condition

Key Features

Paget's Disease

- Denture tightening (arch expansion)
- Chalk-stick fractures
- Leontiasis ossea

Osteopetrosis

- Rugger jersey spine
- Chalk-stick fractures

Fibrous Dysplasia

- Leontiasis ossea
- Chinese script trabeculae
- Ground glass appearance
- Hockey stick femur

Cemento-Ossifying Fibroma

- Leontiasis ossea
- Chinese script trabeculae

Hyperparathyroidism

- Ground glass appearance (Brown tumor)
- Giant cells + vascular stroma + hemosiderin

Cherubism

- Giant cells + vascular stroma + hemosiderin

Central Giant Cell Granuloma

- Giant cells + vascular stroma + hemosiderin

Juvenile Ossifying Fibroma

- More aggressive than COF
- Trabecular type → jaws
- Psammomatoid type → skull base

Mnemonics Flashcards

Mnemonic

Meaning

Paget's Patients Prefer Tight Dentures

Paget's → Denture tightening due to arch expansion

Fibrous Faces Feel Funny

Fibrous dysplasia → Leontiasis ossea, Chinese script, Ground glass, Hockey stick femur

Giant Cells Have Three Homes

Seen in: Hyperparathyroidism, Cherubism, CGCG

  • Inverted Pear-shaped Radiolucency: Globulomaxillary cyst.

    • Associated teeth need not be non-vital.

    • Klestadts’s cyst: Soft tissue variant of Globulomaxillary cyst.

  • Tear Drop-shaped Radiolucency: Lateral Periodontal Cyst.

    • Associated teeth are vital.

  • Cluster of Similar Cysts / Cluster of Grapes: Botryoid Odontogenic Cyst.

Nasopalatine cyst

Radiology

The nasopalatine cyst appears as a well-defined, round radiolucency in the midline of the anterior maxilla . Sometimes it appears to be 'heart-shaped' because of super-imposition of the anterior nasal spine.

Radiological assessment should include examination of the lamina dura of the central incisors (to exclude a radicular cyst) and assessment of size (the nasopalatine foramen may reach a width of as much as 10 mm).

Pathology

The cyst is lined by a layer of pseudostratified ciliated columnar epithelium and/or stratified squamous epithelium. The capsule of the cyst is fibrous and may include the incisive canal neurovascular bundle.


Nasolabial cyst

Radiology

'Bowing' inwards of the anterolateral margin of the nasal cavity has been recorded

Pathology

The nasolabial cyst is lined by non-ciliated pseudostratified columnar epithelium, which is often rich in mucous cells.

  • Chemotherapy Acute Changes: The two common acute changes are hemorrhage and mucositis.

  • Radiosensitivity of Glands: Serous type of glands exhibit more radiosensitivity compared to mucous and mixed glands.

  • Gingivitis - Immune Cells: Neutrophils are the predominant immune cells present in the first stage of gingivitis.

  • Acute Necrotizing Ulcerative Gingivitis (ANUG): Involved papillae show punched out, crater-like necrotic areas covered by grayish pseudomembrane.

  • Drug-Induced Gingival Enlargement: Never seen in edentulous areas, as there is no plaque in these areas for the drug to interact with.

  • Papillon-Lefèvre Syndrome:

    • Cause: Mutation of the cathepsin C gene located on chromosome 11q14.

    • Result: Impaired chemotaxis and phagocytosis, leading to severe periodontitis and palmar/plantar hyperkeratosis.

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