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Oral Pathology - NEETMDS- courses
NEET MDS Lessons
Oral Pathology

  • Pioneer bacteria invade dentinal tubules before clinical signs
  • Tubules contain pure forms:
    • One tubule → cocci
    • Adjacent tubule → bacilli or threads
  • No mixed forms within a single tubule

  • Cheiloscopy: The examination of lip prints.

  • Gustafson's Method for Age Estimation: Includes assessment of:

    • Amount of occlusal attrition

    • Secondary dentine deposition (coronal)

    • Periodontal attachment loss

    • Cementum apposition at root apex

    • Root resorption at apex

    • Dentine translucency

  • Pulp Polyp (Chronic Hyperplastic Pulpitis):

    • Source of epithelium: Implantation of desquamated cells from saliva or by implantation from oral mucosa due to continuous rubbing.

    • Most common teeth: Deciduous molars and permanent first molars.

  • Periapical Granuloma: Always associated with a non-vital tooth.

  • Garre's Osteomyelitis: Another name for Chronic Osteomyelitis with Proliferative Periostitis.

  • Actinomycosis (Sulfur Granules):

    • Yellow sulfur granules: Are actually bacterial colonies.

    • Histopathology: Colonies appear "cotton wool" shaped. (Note: "Cotton wool appearance" is seen radiographically in Paget's disease).

  • Tuberculosis (TB):

    • Diagnosis (Gold Standard): Presence of acid-fast bacilli in sputum.

    • Staining Method: Ziehl-Neelsen staining method is used to identify acid-fast bacilli.

    • Scrofula: TB of cervical lymph nodes.

    • Lupus Vulgaris: TB of skin.

  • Tongue & Gingival Appearance in Systemic Conditions:

    • Strawberry tongue and Raspberry tongue: Seen in stomatitis of Scarlet Fever.

    • Strawberry Gingivitis: Seen in Wegener's Granulomatosis.

  • Lichen Planus:

    • Reticular form: Most common type, characterized by Wickham's striae.

    • Malignant potential: Atrophic and erosive forms are associated with significant malignant transformation risk.

    • Histology: Saw-tooth shaped rete pegs.

  • Solar Elastosis: Characterized clinically by "sailor's skin" or "farmer's skin" (due to chronic sun exposure).

  • Psoriasis & Hereditary Gingival Fibromatosis: Both show test tube-shaped rete pegs histologically.

  • LE Cell Test: LE cells represent rosettes of neutrophils that have phagocytosed other leukocytes (seen in Systemic Lupus Erythematosus).

  • Tzanck Cells: Seen in vesiculobullous conditions like Pemphigus, Herpes Simplex, Varicella, Herpes Zoster, and CMV infection.

  • Ectodermal Dysplasia: Characterized by truncated, conical teeth and missing teeth (hypodontia).

  • Widened Periodontal Ligament Space: Extreme widening seen in Scleroderma and Osteosarcoma.

  • Geographic Tongue & Psoriasis: Share a common histological feature: Munro's abscesses (neutrophilic microabscesses).

Syndrome Confirmatory Sign
Trigeminal Neuralgia Relief with carbamazepine
Eagle’s Syndrome Relief after styloidectomy
Frey’s Syndrome Positive Minor’s starch-iodine test (sweat mapping)
Ramsay Hunt Syndrome Vesicular eruptions in ear/oral mucosa + facial palsy

Paget's Disease

  • Chief Complaint: Denture tightening (due to arch expansion)
  • Fractures: Chalk-stick fractures
  • Facial Feature: Leontiasis ossea (lion-like facies)
  • Radiology: Cotton wool appearance
  • Histology: Jigsaw puzzle pattern
  • Clinical: Bone warm to touch (↑ vascularity)
  • Laboratory: ↑ Alkaline phosphatase (>250 Bodansky units)
  • Other Signs: Osteoporosis circumscripta, platybasia
  • Memory Aid: "Paget's Patients Prefer Tight Dentures"

Osteopetrosis

  • Radiographic Sign: Rugger Jersey Spine (classic)
  • Fractures: Chalk-stick fractures

Fibrous Dysplasia

  • Facial Feature: Leontiasis ossea
  • Histology: Chinese script pattern
  • Radiology:
    • Ground glass appearance
    • Rind sign, orange peel appearance
  • Bone Deformity: Hockey stick/Shepherd's crook deformity (femur)
  • Key Feature: Lesional bone fused with normal bone (vs COF)
  • Memory Aid: "Fibrous Faces Feel Funny"

Cemento-Ossifying Fibroma (COF)

  • Histology: Chinese script pattern
  • Facial Feature: Leontiasis ossea
  • Difference: NOT fused with normal bone (vs Fibrous Dysplasia)

Hyperparathyroidism

  • Radiology: Ground glass appearance (brown tumor)
  • Histology: Numerous giant cells, vascular stroma, hemosiderin deposits

Cherubism & Central Giant Cell Granuloma

  • Histology: Same as hyperparathyroidism (giant cells + vascular stroma + hemosiderin)
  • Note: Cherubism previously called "Familial fibrous dysplasia"
  • Memory Aid: "Giant Cells Have Three Homes" (Hyperparathyroidism, Cherubism, CGCG)

Juvenile Ossifying Fibroma

  • Aggressiveness: More aggressive than Cemento-ossifying fibroma
  • Types:
    • Trabecular type: Common in jaws
    • Psammomatoid type: Involves base of skull

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