NEET MDS Lessons
Oral Pathology
- Pioneer bacteria invade dentinal tubules before clinical signs
- Tubules contain pure forms:
- One tubule → cocci
- Adjacent tubule → bacilli or threads
- No mixed forms within a single tubule
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Cheiloscopy: The examination of lip prints.
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Gustafson's Method for Age Estimation: Includes assessment of:
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Amount of occlusal attrition
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Secondary dentine deposition (coronal)
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Periodontal attachment loss
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Cementum apposition at root apex
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Root resorption at apex
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Dentine translucency
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Pulp Polyp (Chronic Hyperplastic Pulpitis):
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Source of epithelium: Implantation of desquamated cells from saliva or by implantation from oral mucosa due to continuous rubbing.
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Most common teeth: Deciduous molars and permanent first molars.
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Periapical Granuloma: Always associated with a non-vital tooth.
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Garre's Osteomyelitis: Another name for Chronic Osteomyelitis with Proliferative Periostitis.
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Actinomycosis (Sulfur Granules):
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Yellow sulfur granules: Are actually bacterial colonies.
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Histopathology: Colonies appear "cotton wool" shaped. (Note: "Cotton wool appearance" is seen radiographically in Paget's disease).
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Tuberculosis (TB):
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Diagnosis (Gold Standard): Presence of acid-fast bacilli in sputum.
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Staining Method: Ziehl-Neelsen staining method is used to identify acid-fast bacilli.
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Scrofula: TB of cervical lymph nodes.
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Lupus Vulgaris: TB of skin.
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Tongue & Gingival Appearance in Systemic Conditions:
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Strawberry tongue and Raspberry tongue: Seen in stomatitis of Scarlet Fever.
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Strawberry Gingivitis: Seen in Wegener's Granulomatosis.
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Lichen Planus:
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Reticular form: Most common type, characterized by Wickham's striae.
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Malignant potential: Atrophic and erosive forms are associated with significant malignant transformation risk.
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Histology: Saw-tooth shaped rete pegs.
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Solar Elastosis: Characterized clinically by "sailor's skin" or "farmer's skin" (due to chronic sun exposure).
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Psoriasis & Hereditary Gingival Fibromatosis: Both show test tube-shaped rete pegs histologically.
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LE Cell Test: LE cells represent rosettes of neutrophils that have phagocytosed other leukocytes (seen in Systemic Lupus Erythematosus).
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Tzanck Cells: Seen in vesiculobullous conditions like Pemphigus, Herpes Simplex, Varicella, Herpes Zoster, and CMV infection.
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Ectodermal Dysplasia: Characterized by truncated, conical teeth and missing teeth (hypodontia).
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Widened Periodontal Ligament Space: Extreme widening seen in Scleroderma and Osteosarcoma.
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Geographic Tongue & Psoriasis: Share a common histological feature: Munro's abscesses (neutrophilic microabscesses).
| Syndrome | Confirmatory Sign |
|---|---|
| Trigeminal Neuralgia | Relief with carbamazepine |
| Eagle’s Syndrome | Relief after styloidectomy |
| Frey’s Syndrome | Positive Minor’s starch-iodine test (sweat mapping) |
| Ramsay Hunt Syndrome | Vesicular eruptions in ear/oral mucosa + facial palsy |
Paget's Disease
- Chief Complaint: Denture tightening (due to arch expansion)
- Fractures: Chalk-stick fractures
- Facial Feature: Leontiasis ossea (lion-like facies)
- Radiology: Cotton wool appearance
- Histology: Jigsaw puzzle pattern
- Clinical: Bone warm to touch (↑ vascularity)
- Laboratory: ↑ Alkaline phosphatase (>250 Bodansky units)
- Other Signs: Osteoporosis circumscripta, platybasia
- Memory Aid: "Paget's Patients Prefer Tight Dentures"
Osteopetrosis
- Radiographic Sign: Rugger Jersey Spine (classic)
- Fractures: Chalk-stick fractures
Fibrous Dysplasia
- Facial Feature: Leontiasis ossea
- Histology: Chinese script pattern
- Radiology:
- Ground glass appearance
- Rind sign, orange peel appearance
- Bone Deformity: Hockey stick/Shepherd's crook deformity (femur)
- Key Feature: Lesional bone fused with normal bone (vs COF)
- Memory Aid: "Fibrous Faces Feel Funny"
Cemento-Ossifying Fibroma (COF)
- Histology: Chinese script pattern
- Facial Feature: Leontiasis ossea
- Difference: NOT fused with normal bone (vs Fibrous Dysplasia)
Hyperparathyroidism
- Radiology: Ground glass appearance (brown tumor)
- Histology: Numerous giant cells, vascular stroma, hemosiderin deposits
Cherubism & Central Giant Cell Granuloma
- Histology: Same as hyperparathyroidism (giant cells + vascular stroma + hemosiderin)
- Note: Cherubism previously called "Familial fibrous dysplasia"
- Memory Aid: "Giant Cells Have Three Homes" (Hyperparathyroidism, Cherubism, CGCG)
Juvenile Ossifying Fibroma
- Aggressiveness: More aggressive than Cemento-ossifying fibroma
- Types:
- Trabecular type: Common in jaws
- Psammomatoid type: Involves base of skull