NEET MDS Lessons
Oral Pathology
- Pemphigus → Granular IgG intercellular
- Lichen Planus → Linear anti-fibrinogen at BM, with lamina propria extensions
- Cicatricial Pemphigoid → Patchy linear IgG/C3 at BM
- Bullous Pemphigoid → Patchy linear IgG at BMZ
- Erythema Multiforme → Patchy linear fluorescence
- Discoid Lupus (Lesional mucosa) → Speckled pattern (IgG, IgM, IgA, C3, fibrinogen)
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Radicular Cysts: Derived from Rests of Malassez.
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Impacted Canine Associations:
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Most common odontogenic cyst: Dentigerous cyst.
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Most common odontogenic tumor: Adenomatoid Odontogenic Tumor (AOT).
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Eruption Cyst: Considered an extra-alveolar dentigerous cyst (soft tissue counterpart).
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Epithelial Plaques (localized thickenings): Found in:
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Lateral Periodontal Cyst
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Botryoid Odontogenic Cyst
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Gingival Cyst of Adults
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Glandular Odontogenic Cyst
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- SLE → IgG, IgM, IgA deposits at BMZ + superficial lamina propria
- Lichen Planus (Erosive/Atrophic) → Autoimmune T-cell; BMZ involvement
- Cicatricial Pemphigoid → Subepidermal blistering from anti-BMZ antibodies
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Bull Neck: Seen in Diphtheria and Ludwig's Angina.
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Bull's Eye Lesion / Target Lesions: Characteristic of Stevens-Johnson Syndrome and Erythema Multiforme.
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Bull's Teeth: Refers to Taurodontism.
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Circus Rubber Man: Clinical appearance associated with Ehlers-Danlos Syndrome (due to hypermobility and skin elasticity).
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Claw Hands: A physical deformity seen in advanced Scleroderma.
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Coup de Sabre: A linear depression or groove resembling a "saber cut" seen in Facial Hemiatrophy (Parry-Romberg Syndrome) and localized Scleroderma (linear scleroderma).
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CREST Syndrome: A limited form of Scleroderma, characterized by:
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Calcinosis
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Raynaud's phenomenon
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Esophageal dysfunction
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Sclerodactyly
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Telangiectasias
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Crowe's Sign: Axillary or inguinal freckling seen in Neurofibromatosis Type 1.
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Frog Facies: A characteristic facial appearance seen in Crouzon Syndrome (due to midfacial hypoplasia and exophthalmos).
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Gorlin Sign: The ability to touch the tip of the nose with the tongue, seen in Ehlers-Danlos Syndrome (due to increased joint laxity).
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Hockey Stick Deformity of Femur and Shepherd's Crook Sign: Radiographic findings typically associated with Fibrous Dysplasia.
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Parrot's Beak Nose: A nasal deformity seen in Crouzon Syndrome.
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Red Strawberry Tongue and Pastia's Lines: Clinical signs characteristic of Scarlet Fever.
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Rodent Facies: A facial appearance often associated with Thalassemia.
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Simian Stance: A stooped posture, reminiscent of an ape, seen in Paget's Disease of Bone.
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Snail Track Ulcers: Serpiginous, grayish-white lesions on mucous membranes, characteristic of Syphilis (mucous patches in secondary syphilis).
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Socks Feet and Mitten Hands: Refers to syndactyly (fusion of digits) appearing like a sock or mitten, seen in Apert's Syndrome.
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Parrot Beak Shaped Nails: A nail deformity (onychogryphosis) seen in Congenital Syphilis.
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Zone 1 – Normal Dentin:
Healthy tissue; no treatment needed -
Zone 2 – Subtransparent Dentin:
Acid-demineralized, no bacteria, remineralizable; preserve -
Zone 3 – Transparent Dentin:
Softened, no bacterial invasion; remineralizable; preserve -
Zone 4 – Turbid Dentin:
Bacterial invasion; not remineralizable; must be removed -
Zone 5 – Infected Dentin:
Fully decomposed; heavily infected; must be removed
Infantile Osteomyelitis
- Osteomyelitis Maxillaries Neonatarum, Maxillitis of infancy
- Osteomyelitis in the jaws of new born infants occurs almost exclusively in maxilla.
Etiology
- Trauma – through break in mucosa cause during delivery.
- Infection of maxillary sinus
- Paunz & Ramon et al believe that disease caused through infection from the nose.
- Hematogenous spread through streptococci & pneumococci
Clinical features
- Fever, anorexia & intestinal disturbances.
- swelling or redness below the inner canthus of the eye in lacrimal region.
- Followed by marked edema of the eyelids on the affected side.
- Next, alveolus & palate in region of first deciduous molar become swollen.
- Pus discharge from affected sites
D/D for Infantile Osteomyelitis
- Dacrocystitis neonatarum
- Orbital cellulitis
- Ophthalmia neonatarum
- Infantile cortical hyperostosis
TREATMENT
- Intravenous antibiotics, preferably penicillin.
- Culture & sensitivity testing
- Incision & drainage of fluctuant areas
- Sequestrectomy
- Supportive therapy