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- NEETMDS- courses
NEET MDS Lessons
Oral Pathology

  • Pemphigus → Granular IgG intercellular
  • Lichen Planus → Linear anti-fibrinogen at BM, with lamina propria extensions
  • Cicatricial Pemphigoid → Patchy linear IgG/C3 at BM
  • Bullous Pemphigoid → Patchy linear IgG at BMZ
  • Erythema Multiforme → Patchy linear fluorescence
  • Discoid Lupus (Lesional mucosa) → Speckled pattern (IgG, IgM, IgA, C3, fibrinogen)

  • Radicular Cysts: Derived from Rests of Malassez.

  • Impacted Canine Associations:

    • Most common odontogenic cyst: Dentigerous cyst.

    • Most common odontogenic tumor: Adenomatoid Odontogenic Tumor (AOT).

  • Eruption Cyst: Considered an extra-alveolar dentigerous cyst (soft tissue counterpart).

  • Epithelial Plaques (localized thickenings): Found in:

    • Lateral Periodontal Cyst

    • Botryoid Odontogenic Cyst

    • Gingival Cyst of Adults

    • Glandular Odontogenic Cyst

  • SLE → IgG, IgM, IgA deposits at BMZ + superficial lamina propria
  • Lichen Planus (Erosive/Atrophic) → Autoimmune T-cell; BMZ involvement
  • Cicatricial Pemphigoid → Subepidermal blistering from anti-BMZ antibodies

  • Bull Neck: Seen in Diphtheria and Ludwig's Angina.

  • Bull's Eye Lesion / Target Lesions: Characteristic of Stevens-Johnson Syndrome and Erythema Multiforme.

  • Bull's Teeth: Refers to Taurodontism.

  • Circus Rubber Man: Clinical appearance associated with Ehlers-Danlos Syndrome (due to hypermobility and skin elasticity).

  • Claw Hands: A physical deformity seen in advanced Scleroderma.

  • Coup de Sabre: A linear depression or groove resembling a "saber cut" seen in Facial Hemiatrophy (Parry-Romberg Syndrome) and localized Scleroderma (linear scleroderma).

  • CREST Syndrome: A limited form of Scleroderma, characterized by:

    • Calcinosis

    • Raynaud's phenomenon

    • Esophageal dysfunction

    • Sclerodactyly

    • Telangiectasias

  • Crowe's Sign: Axillary or inguinal freckling seen in Neurofibromatosis Type 1.

  • Frog Facies: A characteristic facial appearance seen in Crouzon Syndrome (due to midfacial hypoplasia and exophthalmos).

  • Gorlin Sign: The ability to touch the tip of the nose with the tongue, seen in Ehlers-Danlos Syndrome (due to increased joint laxity).

  • Hockey Stick Deformity of Femur and Shepherd's Crook Sign: Radiographic findings typically associated with Fibrous Dysplasia.

  • Parrot's Beak Nose: A nasal deformity seen in Crouzon Syndrome.

  • Red Strawberry Tongue and Pastia's Lines: Clinical signs characteristic of Scarlet Fever.

  • Rodent Facies: A facial appearance often associated with Thalassemia.

  • Simian Stance: A stooped posture, reminiscent of an ape, seen in Paget's Disease of Bone.

  • Snail Track Ulcers: Serpiginous, grayish-white lesions on mucous membranes, characteristic of Syphilis (mucous patches in secondary syphilis).

  • Socks Feet and Mitten Hands: Refers to syndactyly (fusion of digits) appearing like a sock or mitten, seen in Apert's Syndrome.

  • Parrot Beak Shaped Nails: A nail deformity (onychogryphosis) seen in Congenital Syphilis.

  1. Zone 1 – Normal Dentin:
    Healthy tissue; no treatment needed

  2. Zone 2 – Subtransparent Dentin:
    Acid-demineralized, no bacteria, remineralizable; preserve

  3. Zone 3 – Transparent Dentin:
    Softened, no bacterial invasion; remineralizable; preserve

  4. Zone 4 – Turbid Dentin:
    Bacterial invasion; not remineralizable; must be removed

  5. Zone 5 – Infected Dentin:
    Fully decomposed; heavily infected; must be removed

Infantile Osteomyelitis

  • Osteomyelitis Maxillaries Neonatarum, Maxillitis of infancy
  • Osteomyelitis in the jaws of new born infants occurs almost exclusively in maxilla.

Etiology

  • Trauma – through break in mucosa cause during delivery.
  • Infection of maxillary sinus
  • Paunz & Ramon et al  believe that disease caused through infection from the nose.
  • Hematogenous spread through streptococci & pneumococci

Clinical features

  • Fever, anorexia & intestinal disturbances.
  • swelling or redness below the inner canthus of the eye in lacrimal region.
  • Followed by marked edema of the eyelids on the affected side.
  • Next, alveolus & palate in region of first deciduous molar become swollen.
  • Pus discharge from affected sites

D/D for Infantile Osteomyelitis

  • Dacrocystitis neonatarum
  • Orbital cellulitis
  • Ophthalmia neonatarum
  • Infantile cortical hyperostosis

TREATMENT

  • Intravenous antibiotics, preferably penicillin.
  • Culture & sensitivity testing
  • Incision & drainage of fluctuant areas
  • Sequestrectomy
  • Supportive therapy

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