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Periodontology - NEETMDS- courses
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Periodontology

Localized Aggressive Periodontitis and Necrotizing Ulcerative Gingivitis

Localized Aggressive Periodontitis (LAP)

Localized aggressive periodontitis, previously known as localized juvenile periodontitis, is characterized by specific microbial profiles and clinical features.

  • Microbiota Composition:
    • The microbiota associated with LAP is predominantly composed of:
      • Gram-Negative, Capnophilic, and Anaerobic Rods.
    • Key Organisms:
      • Actinobacillus actinomycetemcomitans: The main organism involved in LAP.
      • Other significant organisms include:
        • Porphyromonas gingivalis
        • Eikenella corrodens
        • Campylobacter rectus
        • Bacteroides capillus
        • Spirochetes (various species).
    • Viral Associations:
      • Herpes viruses, including Epstein-Barr Virus-1 (EBV-1) and Human Cytomegalovirus (HCMV), have also been associated with LAP.

Necrotizing Ulcerative Gingivitis (NUG)

  • Microbial Profile:
    • NUG is characterized by high levels of:
      • Prevotella intermedia
      • Spirochetes (various species).
  • Clinical Features:
    • NUG presents with necrosis of the gingival tissue, pain, and ulceration, often accompanied by systemic symptoms.

Microbial Shifts in Periodontal Disease

When comparing the microbiota across different states of periodontal health, a distinct microbial shift can be identified as the disease progresses from health to gingivitis to periodontitis:

  1. From Gram-Positive to Gram-Negative:

    • Healthy gingival sites are predominantly colonized by gram-positive bacteria, while diseased sites show an increase in gram-negative bacteria.
  2. From Cocci to Rods (and Later to Spirochetes):

    • In health, cocci (spherical bacteria) are prevalent. As the disease progresses, there is a shift towards rod-shaped bacteria, and in advanced stages, spirochetes become more prominent.
  3. From Non-Motile to Motile Organisms:

    • Healthy sites are often dominated by non-motile bacteria, while motile organisms increase in number as periodontal disease develops.
  4. From Facultative Anaerobes to Obligate Anaerobes:

    • In health, facultative anaerobes (which can survive with or without oxygen) are common. In contrast, obligate anaerobes (which thrive in the absence of oxygen) become more prevalent in periodontal disease.
  5. From Fermenting to Proteolytic Species:

    • The microbial community shifts from fermentative bacteria, which primarily metabolize carbohydrates, to proteolytic species that break down proteins, contributing to tissue destruction and inflammation.

Assessing New Attachment in Periodontal Therapy

Assessing new attachment following periodontal therapy is crucial for evaluating treatment outcomes and understanding the healing process. However, various methods of assessment have limitations that must be considered. This lecture will discuss the reliability of different assessment methods for new attachment, including periodontal probing, radiographic analysis, and histologic methods.

1. Periodontal Probing

  • Assessment Method: Periodontal probing is commonly used to measure probing depth and attachment levels before and after therapy.

  • Limitations:

    • Coronal Positioning of Probe Tip: After therapy, when the inflammatory lesion is resolved, the probe tip may stop coronal to the apical termination of the epithelium. This can lead to misleading interpretations of attachment gain.
    • Infrabony Defects: Following treatment of infrabony defects, new bone may form so close to the tooth surface that the probe cannot penetrate. This can result in a false impression of improved attachment levels.
    • Interpretation of Results: A gain in probing attachment level does not necessarily indicate a true gain of connective tissue attachment. Instead, it may reflect improved health of the surrounding tissues, which increases resistance to probe penetration.

2. Radiographic Analysis and Reentry Operations

  • Assessment Method: Radiographic analysis involves comparing radiographs taken before and after therapy to evaluate changes in bone levels. Reentry operations allow for direct inspection of the treated area.

  • Limitations:

    • Bone Fill vs. New Attachment: While radiographs can provide evidence of new bone formation (bone fill), they do not document the formation of new root cementum or a new periodontal ligament. Therefore, radiographic evidence alone cannot confirm the establishment of new attachment.

3. Histologic Methods

  • Assessment Method: Histologic analysis involves examining tissue samples under a microscope to assess the formation of new attachment, including new cementum and periodontal ligament.

  • Advantages:

    • Validity: Histologic methods are considered the only valid approach to assess the formation of new attachment accurately.
  • Limitations:

    • Pre-Therapy Assessment: Accurate assessment of the attachment level prior to therapy is essential for histologic analysis. If the initial attachment level cannot be determined with certainty, it may compromise the validity of the findings.

Plaque Formation

Dental plaque is a biofilm that forms on the surfaces of teeth and is a key factor in the development of dental caries and periodontal disease. The process of plaque formation can be divided into three major phases:

1. Formation of Pellicle on the Tooth Surface

  • Definition: The pellicle is a thin, acellular film that forms on the tooth surface shortly after cleaning.
  • Composition: It is primarily composed of salivary glycoproteins and other proteins that are adsorbed onto the enamel surface.
  • Function:
    • The pellicle serves as a protective barrier for the tooth surface.
    • It provides a substrate for bacterial adhesion, facilitating the subsequent stages of plaque formation.

2. Initial Adhesion & Attachment of Bacteria

  • Mechanism:
    • Bacteria in the oral cavity begin to adhere to the pellicle-coated tooth surface.
    • This initial adhesion is mediated by specific interactions between bacterial adhesins (surface proteins) and the components of the pellicle.
  • Key Bacterial Species:
    • Primary colonizers, such as Streptococcus sanguis and Actinomyces viscosus, are among the first to attach.
  • Importance:
    • Successful adhesion is crucial for the establishment of plaque, as it allows for the accumulation of additional bacteria.

3. Colonization & Plaque Maturation

  • Colonization:
    • Once initial bacteria have adhered, they proliferate and create a more complex community.
    • Secondary colonizers, including gram-negative anaerobic bacteria, begin to join the biofilm.
  • Plaque Maturation:
    • As the plaque matures, it develops a three-dimensional structure, with different bacterial species occupying specific niches within the biofilm.
    • The matrix of extracellular polysaccharides and salivary glycoproteins becomes more pronounced, providing structural integrity to the plaque.
  • Coaggregation:
    • Different bacterial species can adhere to one another through coaggregation, enhancing the complexity of the plaque community.

Composition of Plaque

  • Matrix Composition:
    • Plaque is primarily composed of bacteria embedded in a matrix of salivary glycoproteins and extracellular polysaccharides.
  • Implications for Removal:
    • The dense and cohesive nature of this matrix makes it difficult to remove plaque through simple rinsing or the use of sprays.
    • Effective plaque removal typically requires mechanical means, such as brushing and flossing, to disrupt the biofilm structure.

Periodontal Diseases Associated with Neutrophil Disorders

  1. Acute Necrotizing Ulcerative Gingivitis (ANUG)

    • Description: A severe form of gingivitis characterized by necrosis of the interdental papillae, pain, and foul odor.
    • Association: Neutrophil dysfunction can exacerbate the severity of ANUG, leading to rapid tissue destruction.
  2. Localized Juvenile Periodontitis

    • Description: A form of periodontitis that typically affects adolescents and is characterized by localized bone loss around the permanent teeth.
    • Association: Impaired neutrophil function contributes to the pathogenesis of this condition.
  3. Prepubertal Periodontitis

    • Description: A rare form of periodontitis that occurs in children before puberty, leading to rapid attachment loss and bone destruction.
    • Association: Neutrophil disorders can play a significant role in the development and progression of this disease.
  4. Rapidly Progressive Periodontitis

    • Description: A form of periodontitis characterized by rapid attachment loss and bone destruction, often occurring in young adults.
    • Association: Neutrophil dysfunction may contribute to the aggressive nature of this disease.
  5. Refractory Periodontitis

    • Description: A form of periodontitis that does not respond to conventional treatment and continues to progress despite therapy.
    • Association: Neutrophil disorders may be implicated in the persistent nature of this condition.

Gracey Curettes

Gracey curettes are specialized instruments designed for periodontal therapy, particularly for subgingival scaling and root planing. Their unique design allows for optimal adaptation to the complex anatomy of the teeth and surrounding tissues. This lecture will cover the characteristics, specific uses, and advantages of Gracey curettes in periodontal practice.

  • Gracey curettes are area-specific curettes that come in a set of instruments, each designed and angled to adapt to specific anatomical areas of the dentition.

  • Purpose: They are considered some of the best instruments for subgingival scaling and root planing due to their ability to provide excellent adaptation to complex root anatomy.

Specific Gracey Curette Designs and Uses

  1. Gracey 1/2 and 3/4:

    • Indication: Designed for use on anterior teeth.
    • Application: Effective for scaling and root planing in the anterior region, allowing for precise access to the root surfaces.
  2. Gracey 5/6:

    • Indication: Suitable for anterior teeth and premolars.
    • Application: Versatile for both anterior and premolar areas, providing effective scaling in these regions.
  3. Gracey 7/8 and 9/10:

    • Indication: Designed for posterior teeth, specifically for facial and lingual surfaces.
    • Application: Ideal for accessing the buccal and lingual surfaces of posterior teeth, ensuring thorough cleaning.
  4. Gracey 11/12:

    • Indication: Specifically designed for the mesial surfaces of posterior teeth.
    • Application: Allows for effective scaling of the mesial aspects of molars and premolars.
  5. Gracey 13/14:

    • Indication: Designed for the distal surfaces of posterior teeth.
    • Application: Facilitates access to the distal surfaces of molars and premolars, ensuring comprehensive treatment.

Key Features of Gracey Curettes

  • Area-Specific Design: Each Gracey curette is tailored for specific areas of the dentition, allowing for better access and adaptation to the unique contours of the teeth.

  • Offset Blade: Unlike universal curettes, the blade of a Gracey curette is not positioned at a 90-degree angle to the lower shank. Instead, the blade is angled approximately 60 to 70 degrees from the lower shank, which is referred to as an "offset blade." This design enhances the instrument's ability to adapt to the tooth surface and root anatomy.

Advantages of Gracey Curettes

  1. Optimal Adaptation: The area-specific design and offset blade allow for better adaptation to the complex anatomy of the roots, making them highly effective for subgingival scaling and root planing.

  2. Improved Access: The angled blades enable clinicians to access difficult-to-reach areas, such as furcations and concavities, which are often challenging with standard instruments.

  3. Enhanced Efficiency: The design of Gracey curettes allows for more efficient removal of calculus and biofilm from root surfaces, contributing to improved periodontal health.

  4. Reduced Tissue Trauma: The precise design minimizes trauma to the surrounding soft tissues, promoting better healing and patient comfort.

Finger Rests in Dental Instrumentation

Use of finger rests is essential for providing stability and control during procedures. A proper finger rest allows for more precise movements and reduces the risk of hand fatigue.

Importance of Finger Rests

  • Stabilization: Finger rests serve to stabilize the hand and the instrument, providing a firm fulcrum that enhances control during procedures.
  • Precision: A stable finger rest allows for more accurate instrumentation, which is crucial for effective treatment and patient safety.
  • Reduced Fatigue: By providing support, finger rests help reduce hand and wrist fatigue, allowing the clinician to work more comfortably for extended periods.

Types of Finger Rests

  1. Conventional Finger Rest:

    • Description: The finger rest is established on the tooth surfaces immediately adjacent to the working area.
    • Application: This is the most common type of finger rest, providing direct support for the hand while working on a specific tooth. It allows for precise movements and control during instrumentation.
  2. Cross Arch Finger Rest:

    • Description: The finger rest is established on the tooth surfaces on the other side of the same arch.
    • Application: This technique is useful when working on teeth that are not directly adjacent to the finger rest. It provides stability while allowing access to the working area from a different angle.
  3. Opposite Arch Finger Rest:

    • Description: The finger rest is established on the tooth surfaces of the opposite arch (e.g., using a mandibular arch finger rest for instrumentation on the maxillary arch).
    • Application: This type of finger rest is particularly beneficial when accessing the maxillary teeth from the mandibular arch, providing a stable fulcrum while maintaining visibility and access.
  4. Finger on Finger Rest:

    • Description: The finger rest is established on the index finger or thumb of the non-operating hand.
    • Application: This technique is often used in areas where traditional finger rests are difficult to establish, such as in the posterior regions of the mouth. It allows for flexibility and adaptability in positioning.

Some important points about the periodontal pocket :
·Soft tissue of pocket wall shows both proliferative & degenerative changes
·Most severe degenerative changes are seen on the lateral wall of pocket
·Plasma cells are the predominant infiltrate (80%). Others include lymphocytes & a scattering of PMNs
·Height of junctional epithelium shortened to only 50-100µm
·Severity of degenerative changes is not linked to pocket depth
·Junctional epithelium starts to lose attachment to tooth when PMN infiltration in junctional epithelium increases above 60%.

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