NEET MDS Lessons
Oral and Maxillofacial Surgery
Management of Septic Shock
Septic shock is a life-threatening condition characterized by severe infection leading to systemic inflammation, vasodilation, and impaired tissue perfusion. Effective management is crucial to improve outcomes and reduce mortality. The management of septic shock should be based on several key principles:
Key Principles of Management
-
Early and Effective Volume Replacement:
- Fluid Resuscitation: Initiate aggressive fluid resuscitation with crystalloids (e.g., normal saline or lactated Ringer's solution) to restore intravascular volume and improve circulation.
- Goal: Aim for a rapid infusion of 30 mL/kg of crystalloid fluids within the first 3 hours of recognition of septic shock.
-
Restoration of Tissue Perfusion:
- Monitoring: Continuous monitoring of vital signs, urine output, and laboratory parameters to assess the effectiveness of resuscitation.
- Target Blood Pressure: In most patients, a systolic blood pressure of 90 to 100 mm Hg or a mean arterial pressure (MAP) of 70 to 75 mm Hg is considered acceptable.
-
Adequate Oxygen Supply to Cells:
- Oxygen Delivery: Ensure adequate oxygen delivery to tissues by maintaining hemoglobin saturation (SaO2) above 95% and arterial oxygen tension (PaO2) above 60 mm Hg.
- Hematocrit: Maintain hematocrit levels above 30% to ensure sufficient oxygen-carrying capacity.
-
Control of Infection:
- Antibiotic Therapy: Administer broad-spectrum antibiotics as soon as possible, ideally within the first hour of recognizing septic shock. Adjust based on culture results and sensitivity.
- Source Control: Identify and control the source of infection (e.g., drainage of abscesses, removal of infected devices).
Pharmacological Management
-
Vasopressor Therapy:
- Indication: If hypotension persists despite adequate fluid resuscitation, vasopressors are required to increase arterial pressure.
- First-Line Agents:
- Dopamine: Often the first choice due to its ability to maintain organ blood flow, particularly to the kidneys and mesenteric circulation. Typical dosing is 20 to 25 micrograms/kg/min.
- Noradrenaline (Norepinephrine): Should be added if hypotension persists despite dopamine administration. It is the preferred vasopressor for septic shock due to its potent vasoconstrictive properties.
-
Cardiac Output and Myocardial Function:
- Dobutamine: If myocardial depression is suspected (e.g., low cardiac output despite adequate blood pressure), dobutamine can be added to improve cardiac output without significantly increasing arterial pressure. This helps restore oxygen delivery to tissues.
- Monitoring: Continuous monitoring of cardiac output and systemic vascular resistance is essential to assess the effectiveness of treatment.
Additional Considerations
- Supportive Care: Provide supportive care, including mechanical ventilation if necessary, and monitor for complications such as acute respiratory distress syndrome (ARDS) or acute kidney injury (AKI).
- Nutritional Support: Early enteral nutrition should be initiated as soon as feasible to support metabolic needs and improve outcomes.
- Reassessment: Regularly reassess the patient's hemodynamic status and adjust fluid and medication therapy accordingly.
Submasseteric Space Infection
Submasseteric space infection refers to an infection that occurs in the submasseteric space, which is located beneath the masseter muscle. This space is clinically significant in the context of dental infections, particularly those arising from the lower third molars (wisdom teeth) or other odontogenic sources. Understanding the anatomy and potential spread of infections in this area is crucial for effective diagnosis and management.
Anatomy of the Submasseteric Space
-
Location:
- The submasseteric space is situated beneath the masseter muscle, which is a major muscle involved in mastication (chewing).
- This space is bordered superiorly by the masseter muscle and inferiorly by the lower border of the ramus of the mandible.
-
Boundaries:
- Inferior Boundary: The extension of an abscess or infection inferiorly is limited by the firm attachment of the masseter muscle to the lower border of the ramus of the mandible. This attachment creates a barrier that can restrict the spread of infection downward.
- Anterior Boundary: The forward spread of infection beyond the anterior border of the ramus is restricted by the anterior tail of the tendon of the temporalis muscle, which inserts into the anterior border of the ramus. This anatomical feature helps to contain infections within the submasseteric space.
-
Posterior Boundary: The posterior limit of the submasseteric space is generally defined by the posterior border of the ramus of the mandible.
Clinical Implications
-
Sources of Infection:
- Infections in the submasseteric space often arise from odontogenic
sources, such as:
- Pericoronitis associated with impacted lower third molars.
- Dental abscesses from other teeth in the mandible.
- Periodontal infections.
- Infections in the submasseteric space often arise from odontogenic
sources, such as:
-
Symptoms:
- Patients with submasseteric space infections may present with:
- Swelling and tenderness in the area of the masseter muscle.
- Limited mouth opening (trismus) due to muscle spasm or swelling.
- Pain that may radiate to the ear or temporomandibular joint (TMJ).
- Fever and systemic signs of infection in more severe cases.
- Patients with submasseteric space infections may present with:
-
Diagnosis:
- Diagnosis is typically made through clinical examination and imaging studies, such as panoramic radiographs or CT scans, to assess the extent of the infection and its relationship to surrounding structures.
-
Management:
- Treatment of submasseteric space infections usually involves:
- Antibiotic Therapy: Broad-spectrum antibiotics are often initiated to control the infection.
- Surgical Intervention: Drainage of the abscess may be necessary, especially if there is significant swelling or if the patient is not responding to conservative management. Incision and drainage can be performed intraorally or extraorally, depending on the extent of the infection.
- Management of the Source: Addressing the underlying dental issue, such as extraction of an impacted tooth or treatment of a dental abscess, is essential to prevent recurrence.
- Treatment of submasseteric space infections usually involves:
Lateral Pharyngeal Space
The lateral pharyngeal space is an important anatomical area in the neck that plays a significant role in various clinical conditions, particularly infections. Here’s a detailed overview of its anatomy, divisions, clinical significance, and potential complications.
Anatomy
- Shape and Location: The lateral pharyngeal space is a
potential cone-shaped space or cleft.
- Base: The base of the cone is located at the base of the skull.
- Apex: The apex extends down to the greater horn of the hyoid bone.
- Divisions: The space is divided into two compartments
by the styloid process:
- Anterior Compartment: Located in front of the styloid process.
- Posterior Compartment: Located behind the styloid process.
Boundaries
- Medial Boundary: The lateral wall of the pharynx.
- Lateral Boundary: The medial surface of the mandible and the muscles of the neck.
- Superior Boundary: The base of the skull.
- Inferior Boundary: The greater horn of the hyoid bone.
Contents
The lateral pharyngeal space contains various important structures, including:
- Muscles: The stylopharyngeus and the superior pharyngeal constrictor muscles.
- Nerves: The glossopharyngeal nerve (CN IX) and the vagus nerve (CN X) may be present in this space.
- Vessels: The internal carotid artery and the internal jugular vein are closely associated with this space, particularly within the carotid sheath.
Clinical Significance
-
Infection Risk: Infection in the lateral pharyngeal space can be extremely serious due to its proximity to vital structures, particularly the carotid sheath, which contains the internal carotid artery, internal jugular vein, and cranial nerves.
-
Potential Complications:
- Spread of Infection: Infections can spread from the lateral pharyngeal space to other areas, including the mediastinum, leading to life-threatening conditions such as mediastinitis.
- Airway Compromise: Swelling or abscess formation in this space can lead to airway obstruction, necessitating urgent medical intervention.
- Vascular Complications: The close relationship with the carotid sheath means that infections can potentially involve the carotid artery or jugular vein, leading to complications such as thrombosis or carotid artery rupture.
Diagnosis and Management
-
Diagnosis:
- Clinical examination may reveal signs of infection, such as fever, neck swelling, and difficulty swallowing.
- Imaging studies, such as CT scans, are often used to assess the extent of infection and involvement of surrounding structures.
-
Management:
- Antibiotics: Broad-spectrum intravenous antibiotics are typically initiated to manage the infection.
- Surgical Intervention: In cases of abscess formation or significant swelling, surgical drainage may be necessary to relieve pressure and remove infected material.
Sutures
Sutures are an essential component of oral surgery, used to close wounds, secure grafts, and stabilize tissues after surgical procedures. The choice of suture material and sterilization methods is critical for ensuring effective healing and minimizing complications. Below is a detailed overview of suture materials, specifically focusing on catgut and its sterilization methods.
Types of Suture Materials
-
Absorbable Sutures: These sutures are designed to be broken down and absorbed by the body over time. They are commonly used in oral surgery for soft tissue closure where long-term support is not necessary.
- Catgut: A natural absorbable suture made from the intestinal mucosa of sheep or cattle. It is widely used in oral surgery due to its good handling properties and ability to promote healing.
-
Non-Absorbable Sutures: These sutures remain in the body until they are removed or until they eventually break down. They are used in situations where long-term support is needed.
Catgut Sutures
Sterilization Methods: Catgut sutures must be properly sterilized to prevent infection and ensure safety during surgical procedures. Two common sterilization methods for catgut are:
-
Gamma Radiation Sterilization:
- Process: Catgut sutures are sterilized using gamma radiation, typically at a dose of 2.5 mega-rads. This method effectively kills bacteria and other pathogens without compromising the integrity of the suture material.
- Preservation: After sterilization, catgut sutures are preserved in a solution of 2.5 percent formaldehyde and denatured absolute alcohol. This solution helps maintain the sterility of the sutures while preventing degradation.
- Packaging: The sutures are stored in spools or foils to protect them from contamination until they are ready for use.
-
Chromic Acid Method:
- Process: In this method, catgut sutures are immersed in a solution containing 20 percent chromic acid and five parts of 8.5 percent glycerin. This process not only sterilizes the sutures but also enhances their durability.
- Benefits: The chromic acid treatment helps to secure a longer stay in the pack, meaning that the sutures can maintain their strength and integrity for a more extended period before being used. This is particularly beneficial in surgical settings where sutures may need to be stored for some time.
Characteristics of Catgut Sutures
- Absorbability: Catgut sutures are absorbable, typically losing their tensile strength within 7 to 14 days, depending on the type (plain or chromic).
- Tensile Strength: They provide good initial tensile strength, making them suitable for various surgical applications.
- Biocompatibility: Being a natural product, catgut is generally well-tolerated by the body, although some patients may have sensitivities or allergic reactions.
- Handling: Catgut sutures are easy to handle and tie, making them a popular choice among surgeons.
Applications in Oral Surgery
- Soft Tissue Closure: Catgut sutures are commonly used for closing incisions in soft tissues of the oral cavity, such as after tooth extractions, periodontal surgeries, and mucosal repairs.
- Graft Stabilization: They can also be used to secure grafts in procedures like guided bone regeneration or soft tissue grafting.
Fixation of Condylar Fractures
Condylar fractures of the mandible can be challenging to manage due to their location and the functional demands placed on the condylar region. Various fixation techniques have been developed to achieve stable fixation and promote healing. Below is an overview of the different methods of fixation for condylar fractures, including their advantages, disadvantages, and indications.
1. Miniplate Osteosynthesis
-
Overview:
- Miniplate osteosynthesis involves the use of condylar plates and screw systems designed to withstand biochemical forces, minimizing micromotion at the fracture site.
-
Primary Bone Healing:
- Under optimal conditions of stability and fracture reduction, primary bone healing can occur, allowing new bone to form along the fracture surface without the formation of fibrous tissue.
-
Plate Placement:
- High condylar fractures may accommodate only one plate with two screws above and below the fracture line, parallel to the posterior border, providing adequate stability in most cases.
- For low condylar fractures, two plates may be required. The posterior plate should parallel the posterior ascending ramus, while the anterior plate can be angulated across the fracture line.
-
Mechanical Advantage:
- The use of two miniplates at the anterior and posterior borders of the condylar neck restores tension and compression trajectories, neutralizing functional stresses in the condylar neck.
-
Research Findings:
- Studies have shown that the double mini plate method is the only system able to withstand normal loading forces in cadaver mandibles.
2. Dynamic Compression Plating
-
Overview:
- Dynamic compression plating is generally not recommended for condylar fractures due to the oblique nature of the fractures, which can lead to overlap of fragment ends and loss of ramus height.
-
Current Practice:
- The consensus is that treatment is adequate with miniplates placed in a neutral mode, avoiding the complications associated with dynamic compression plating.
3. Lag Screw Osteosynthesis
-
Overview:
- First described for condylar fractures by Wackerbauer in 1962, lag screws provide a biomechanically advantageous method of fixation.
-
Mechanism:
- A true lag screw has threads only on the distal end, allowing for compression when tightened against the near cortex. This central placement of the screw enhances stability.
-
Advantages:
- Rapid application of rigid fixation and close approximation of fractured parts due to significant compression generated.
- Less traumatic than miniplates, as there is no need to open the joint capsule.
-
Disadvantages:
- Risk of lateralization and rotation of the condylar head if the screw is not placed centrally.
- Requires a steep learning curve for proper application.
-
Contraindications:
- Not suitable for cases with loss of bone in the fracture gap or comminution that could lead to displacement when compression is applied.
-
Popular Options:
- The Eckelt screw is one of the most widely used lag screws in current practice.
4. Pin Fixation
-
Overview:
- Pin fixation involves the use of 1.3 mm Kirschner wires (K-wires) placed into the condyle under direct vision.
-
Technique:
- This method requires an open approach to the condylar head and traction applied to the lower border of the mandible. A minimum of three convergent K-wires is typically needed to ensure stability.
5. Resorbable Pins and Plates
-
Overview:
- Resorbable fixation devices may take more than two years to fully resorb. Materials used include self-reinforced poly-L-lactide screws (SR-PLLA), polyglycolide pins, and absorbable alpha-hydroxy polyesters.
-
Indications:
- These materials are particularly useful in pediatric patients or in situations where permanent hardware may not be desirable.
Characteristics of Middle-Third Facial Fractures
Middle-third facial fractures, often referred to as "midfacial fractures," involve the central portion of the face, including the nasal bones, maxilla, and zygomatic arch. These fractures can result from various types of trauma, such as motor vehicle accidents, falls, or physical assaults. The following points highlight the key features and clinical implications of middle-third facial fractures:
1. Oedema of the Middle Third of the Face
-
Rapid Development: Oedema (swelling) in the middle third of the face develops quickly after the injury, leading to a characteristic "balloon" appearance. This swelling is due to the accumulation of fluid in the soft tissues of the face.
-
Absence of Deep Cervical Fascia: The unique anatomical structure of the middle third of the face contributes to this swelling. The absence of deep cervical fascia in this region allows for the rapid spread of fluid, resulting in pronounced oedema.
-
Clinical Presentation: In the early stages following injury, patients with middle-third fractures often present with similar facial appearances due to the characteristic swelling. This can make diagnosis based solely on visual inspection challenging.
2. Lengthening of the Face
-
Displacement of the Middle Third: The downward and backward displacement of the middle third of the facial skeleton can lead to an increase in the overall length of the face. This displacement forces the mandible to open, which can result in a change in occlusion, particularly in the molar region.
-
Gagging of Occlusion: The altered position of the mandible can lead to a malocclusion, where the upper and lower teeth do not align properly. This can cause discomfort and difficulty in chewing or speaking.
-
Delayed Recognition of Lengthening: The true increase in facial length may not be fully appreciated until the initial oedema subsides. As the swelling decreases, the changes in facial structure become more apparent.
3. Nasal Obstruction
-
Blood Clots in the Nares: Following a middle-third fracture, the nares (nostrils) may become obstructed by blood clots, leading to nasal congestion. This can significantly impact the patient's ability to breathe through the nose.
-
Mouth Breathing: Due to the obstruction, patients are often forced to breathe through their mouths, which can lead to additional complications, such as dry mouth and increased risk of respiratory infections.
Management of Nasal Complex Fractures
Nasal complex fractures involve injuries to the nasal bones and surrounding structures, including the nasal septum, maxilla, and sometimes the orbits. Proper management is crucial to restore function and aesthetics.
Anesthesia Considerations
- Local Anesthesia:
- Nasal complex fractures can be reduced under local anesthesia, which may be sufficient for less complicated cases or when the patient is cooperative.
- General Anesthesia:
- For more complex fractures or when significant manipulation of the nasal structures is required, general anesthesia is preferred.
- Per-oral Endotracheal Tube: This method allows for better airway management and control during the procedure.
- Throat Pack: A throat pack is often used to minimize the risk of aspiration and to manage any potential hemorrhage, which can be profuse in these cases.
Surgical Technique
-
Reduction of Fractures:
- The primary goal is to realign the fractured nasal bones and restore the normal anatomy of the nasal complex.
- Manipulation of Fragments:
- Walsham’s Forceps: These are specialized instruments used to grasp and manipulate the nasal bone fragments during reduction.
- Asche’s Forceps: Another type of forceps that can be used for similar purposes, allowing for precise control over the fractured segments.
-
Post-Reduction Care:
- After the reduction, the nasal structures may be stabilized using splints or packing to maintain alignment during the healing process.
- Monitoring for complications such as bleeding, infection, or airway obstruction is essential.