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Conservative Dentistry

Carisolv

Carisolv is a dental caries removal system that offers a unique approach to the treatment of carious dentin. It differs from traditional methods, such as Caridex, by utilizing amino acids and a lower concentration of sodium hypochlorite. Below is an overview of its components, mechanism of action, application process, and advantages.

1. Components of Carisolv

A. Red Gel (Solution A)

  • Composition:
    • Amino Acids: Contains 0.1 M of three amino acids:
      • I-Glutamic Acid
      • I-Leucine
      • I-Lysine
    • Sodium Hydroxide (NaOH): Used to adjust pH.
    • Sodium Hypochlorite (NaOCl): Present at a lower concentration compared to Caridex.
    • Erythrosine: A dye that provides color to the gel, aiding in visualization during application.
    • Purified Water: Used as a solvent.

B. Clear Liquid (Solution B)

  • Composition:
    • Sodium Hypochlorite (NaOCl): Contains 0.5% NaOCl w/v, which contributes to the antimicrobial properties of the solution.

C. Storage and Preparation

  • Temperature: The two separate gels are stored at 48°C before use and are allowed to return to room temperature prior to application.

2. Mechanism of Action

  • Softening Carious Dentin: Carisolv is designed to soften carious dentin by chemically disrupting denatured collagen within the affected tissue.
  • Collagen Disruption: The amino acids in the formulation play a crucial role in breaking down the collagen matrix, making it easier to remove the softened carious dentin.
  • Scraping Away: After the dentin is softened, it is removed using specially designed hand instruments, allowing for precise and effective caries removal.

3. pH and Application Time

  • Resultant pH: The pH of Carisolv is approximately 11, which is alkaline and conducive to the softening process.
  • Application Time: The recommended application time for Carisolv is between 30 to 60 seconds, allowing for quick treatment of carious lesions.

4. Advantages

  • Minimally Invasive: Carisolv offers a minimally invasive approach to caries removal, preserving healthy tooth structure while effectively treating carious dentin.
  • Reduced Need for Rotary Instruments: The chemical action of Carisolv reduces the reliance on traditional rotary instruments, which can be beneficial for patients with anxiety or those requiring a gentler approach.
  • Visualization: The presence of erythrosine allows for better visualization of the treated area, helping clinicians ensure complete removal of carious tissue.

Tooth Deformation Under Load

Biomechanical Properties of Teeth

  • Deformation (Strain): Teeth are not rigid structures; they undergo deformation (strain) during normal loading. This deformation is a natural response to the forces applied during chewing and other functional activities.
  • Intraoral Loads: The loads experienced by teeth can vary widely, with reported forces ranging from 10 to 431 N (1 N = 0.225 lb of force). A functional load of approximately 70 N is considered clinically normal.

Factors Influencing Load Distribution

  • Number of Teeth: The total number of teeth in the arch affects how forces are distributed. More teeth can share the load, reducing the stress on individual teeth.
  • Type of Occlusion: The occlusal relationship (how the upper and lower teeth come together) influences how forces are transmitted through the dental arch.
  • Occlusal Habits: Habits such as bruxism (teeth grinding) can significantly increase the forces applied to individual teeth, leading to greater strain and potential damage.

Clinical Implications

  • Restorative Considerations: Understanding the biomechanical behavior of teeth under load is essential for designing restorations that can withstand functional forces without failure.
  • Patient Management: Awareness of occlusal habits, such as bruxism, can guide clinicians in developing appropriate treatment plans, including the use of occlusal splints or other interventions to protect teeth from excessive forces.

Antimicrobial Agents in Dental Care

Antimicrobial agents play a crucial role in preventing dental caries and managing oral health. Various agents are available, each with specific mechanisms of action, antibacterial activity, persistence in the mouth, and potential side effects. This guide provides an overview of key antimicrobial agents used in dentistry, their properties, and their applications.

1. Overview of Antimicrobial Agents

A. General Use

  • Antimicrobial agents are utilized to prevent caries and manage oral microbial populations. While antibiotics may be considered in rare cases, their systemic effects must be carefully evaluated.
  • Fluoride: Known for its antimicrobial effects, fluoride helps reduce the incidence of caries.
  • Chlorhexidine: This agent has been widely used for its beneficial results in oral health, particularly in periodontal therapy and caries prevention.

2. Chlorhexidine

A. Properties and Use

  • Initial Availability: Chlorhexidine was first introduced in the United States as a rinse for periodontal therapy, typically prescribed as a 0.12% rinse for high-risk patients for short-term use.
  • Varnish Application: In other countries, chlorhexidine is used as a varnish, with professional application being the most effective mode. Chlorhexidine varnish enhances remineralization and decreases the presence of mutans streptococci (MS).

B. Mechanism of Action

  • Antiseptic Properties: Chlorhexidine acts as an antiseptic, preventing bacterial adherence and reducing microbial counts.

C. Application and Efficacy

  • Home Use: Chlorhexidine is prescribed for home use at bedtime as a 30-second rinse. This timing allows for better interaction with MS organisms due to decreased salivary flow.
  • Duration of Use: Typically used for about 2 weeks, chlorhexidine can reduce MS counts to below caries-potential levels, with sustained effects lasting 12 to 26 weeks.
  • Professional Application: It can also be applied professionally once a week for several weeks, with monitoring of microbial counts to assess effectiveness.

D. Combination with Other Measures

  • Chlorhexidine may be used in conjunction with other preventive measures for high-risk patients.

 Antimicrobial Agents

A. Antibiotics

These agents inhibit bacterial growth or kill bacteria by targeting specific cellular processes.

Agent Mechanism of Action Spectrum of Activity Persistence in Mouth Side Effects
Vancomycin Blocks cell-wall synthesis Narrow (mainly Gram-positive) Short Can increase gram-negative bacterial flora
Kanamycin Blocks protein synthesis Broad Short Not specified
Actinobolin Blocks protein synthesis Targets Streptococci Long Not specified

B. Bis-Biguanides

These are antiseptics that prevent bacterial adherence and reduce plaque formation.

Agent Mechanism of Action Spectrum of Activity Persistence in Mouth Side Effects
Alexidine Antiseptic; prevents bacterial adherence Broad Long Bitter taste; stains teeth and tongue brown; mucosal irritation
Chlorhexidine Antiseptic; prevents bacterial adherence Broad Long Bitter taste; stains teeth and tongue brown; mucosal irritation

C. Halogens

Halogen-based compounds work as bactericidal agents by disrupting microbial cell function.

Agent Mechanism of Action Spectrum of Activity Persistence in Mouth Side Effects
Iodine Bactericidal (kills bacteria) Broad Short Metallic taste

D. Fluoride

Fluoride compounds help prevent dental caries by inhibiting bacterial metabolism and strengthening enamel.

Concentration Mechanism of Action Spectrum of Activity Persistence in Mouth Side Effects
1–10 ppm Reduces acid production in bacteria Broad Long Increases enamel resistance to caries attack; fluorosis with chronic high doses in developing teeth
250 ppm Bacteriostatic (inhibits bacterial growth) Broad Long Not specified
1000 ppm Bactericidal (kills bacteria) Broad Long Not specified

Summary & Key Takeaways:

  • Antibiotics target specific bacterial processes but may lead to resistance or unwanted microbial shifts.
  • Bis-Biguanides (e.g., Chlorhexidine) are effective but cause staining and taste disturbances.
  • Halogens (e.g., Iodine) are broad-spectrum but may have unpleasant taste.
  • Fluoride plays a dual role: it reduces bacterial acid production and strengthens enamel.

Antimicrobial agents in operative dentistry include a variety of substances used to prevent infections and enhance oral health. Key agents include:

  1. Chlorhexidine: A broad-spectrum antiseptic that prevents bacterial adherence and is effective in reducing mutans streptococci. It can be used as a rinse or varnish.

  2. Fluoride: Offers antimicrobial effects at various concentrations, enhancing enamel resistance to caries and reducing acid production.

  3. Antibiotics: Such as amoxicillin and metronidazole, are used in specific cases to control infections, with careful consideration of systemic effects.

  4. Bis Biguanides: Agents like alexidine and chlorhexidine, which have long-lasting effects and can cause staining and irritation.

  5. Halogens: Iodine is bactericidal but has a short persistence in the mouth and may cause a metallic taste.

These agents are crucial for managing oral health, particularly in high-risk patients. ## Other Antimicrobial Agents in Operative Dentistry

In addition to the commonly known antimicrobial agents, several other substances are utilized in operative dentistry to prevent infections and promote oral health. Here’s a detailed overview of these agents:

1. Antiseptic Agents

  • Triclosan:

    • Mechanism of Action: A chlorinated bisphenol that disrupts bacterial cell membranes and inhibits fatty acid synthesis.
    • Applications: Often found in toothpaste and mouthwashes, it is effective in reducing plaque and gingivitis.
    • Persistence: Moderate substantivity, allowing for prolonged antibacterial effects.
  • Essential Oils:

    • Components: Includes thymol, menthol, and eucalyptol.
    • Mechanism of Action: Disrupts bacterial cell membranes and has anti-inflammatory properties.
    • Applications: Commonly used in mouthwashes, they can reduce plaque and gingivitis effectively.

2. Enzymatic Agents

  • Enzymes:
    • Mechanism of Action: Certain enzymes can activate salivary antibacterial mechanisms, aiding in the breakdown of biofilms.
    • Applications: Enzymatic toothpastes are designed to enhance the natural antibacterial properties of saliva.

3. Chemical Plaque Control Agents

  • Zinc Compounds:

    • Zinc Citrate:
      • Mechanism of Action: Exhibits antibacterial properties and inhibits plaque formation.
      • Applications: Often combined with other agents like triclosan in toothpaste formulations.
  • Sanguinarine:

    • Source: A plant extract with antimicrobial properties.
    • Applications: Available in some toothpaste and mouthwash formulations, it helps in reducing plaque and gingivitis.

4. Irrigation Solutions

  • Povidone Iodine:

    • Mechanism of Action: A broad-spectrum antiseptic that kills bacteria, viruses, and fungi.
    • Applications: Used for irrigation during surgical procedures to reduce the risk of infection.
  • Hexetidine:

    • Mechanism of Action: An antiseptic that disrupts bacterial cell membranes.
    • Applications: Found in mouthwashes, it has minimal effects on plaque but can help in managing oral infections.

5. Photodynamic Therapy (PDT)

  • Mechanism of Action: Involves the use of light-activated compounds that produce reactive oxygen species to kill bacteria.
  • Applications: Used in the treatment of periodontal diseases and localized infections, PDT can effectively reduce bacterial load without the use of traditional antibiotics.

6. Low-Level Laser Therapy (LLLT)

  • Mechanism of Action: Utilizes specific wavelengths of light to promote healing and reduce inflammation.
  • Applications: Effective in managing pain and promoting tissue repair in dental procedures, it can also help in controlling infections.

Onlay Preparation

Onlay preparations are a type of indirect restoration used to restore teeth that have significant loss of structure but still retain enough healthy tooth structure to support a restoration. Onlays are designed to cover one or more cusps of a tooth and are often used when a full crown is not necessary.

1. Definition of Onlay

A. Onlay

  • An onlay is a restoration that is fabricated using an indirect procedure, covering one or more cusps of a tooth. It is designed to restore the tooth's function and aesthetics while preserving as much healthy tooth structure as possible.

2. Indications for Onlay Preparation

  • Extensive Caries: When a tooth has significant decay that cannot be effectively treated with a filling but does not require a full crown.
  • Fractured Teeth: For teeth that have fractured cusps or significant structural loss.
  • Strengthening: To reinforce a tooth that has been weakened by previous restorations or caries.

3. Onlay Preparation Procedure

A. Initial Assessment

  • Clinical Examination: Assess the extent of caries or damage to determine if an onlay is appropriate.
  • Radiographic Evaluation: Use X-rays to evaluate the tooth structure and surrounding tissues.

B. Tooth Preparation

  1. Burs Used:

    • Commonly used burs include No. 169 L for initial cavity preparation and No. 271 for refining the preparation.
  2. Cavity Preparation:

    • Occlusal Entry: The initial occlusal entry should be approximately 1.5 mm deep.
    • Divergence of Walls: All cavity walls should diverge occlusally by 2-5 degrees:
      • 2 degrees: For short vertical walls.
      • 5 degrees: For long vertical walls.
  3. Proximal Box Preparation:

    • The proximal box margins should clear adjacent teeth by 0.2-0.5 mm, with 0.5 ± 0.2 mm being ideal.

C. Bevels and Flares

  1. Facial and Lingual Flares:

    • Primary and secondary flares should be created on the facial and lingual proximal walls to form the walls in two planes.
    • The secondary flare widens the proximal box, allowing for better access and cleaning.
  2. Gingival Bevels:

    • Should be 0.5-1 mm wide and blend with the secondary flare, resulting in a marginal metal angle of 30 degrees.
  3. Occlusal Bevels:

    • Present on the cavosurface margins of the cavity on the occlusal surface, approximately 1/4th the depth of the respective wall, resulting in a marginal metal angle of 40 degrees.

4. Dimensions for Onlay Preparation

A. Depth of Preparation

  • Occlusal Depth: Approximately 1.5 mm to ensure adequate thickness of the restorative material.
  • Proximal Box Depth: Should be sufficient to accommodate the onlay while maintaining the integrity of the tooth structure.

B. Marginal Angles

  • Facial and Lingual Margins: Should be prepared with a 30-degree angle for burnishability and strength.
  • Enamel Margins: Ideally, the enamel margins should be blunted to a 140-degree angle to enhance strength.

C. Cusp Reduction

  • Cusp Coverage: Cusp reduction is indicated when more than 1/2 of a cusp is involved, and mandatory when 2/3 or more is involved.
  • Uniform Metal Thickness: The reduction must provide for a uniform metal thickness of approximately 1.5 mm over the reduced cusps.
  • Facial Cusp Reduction: For maxillary premolars and first molars, the reduction of the facial cusp should be 0.75-1 mm for esthetic reasons.

D. Reverse Bevel

  • Definition: A bevel on the margins of the reduced cusp, extending beyond any occlusal contact with opposing teeth, resulting in a marginal metal angle of 30 degrees.

5. Considerations for Onlay Preparation

  • Retention and Resistance: The preparation should be designed to maximize retention and resistance form, which may include the use of proximal retentive grooves and collar features.
  • Aesthetic Considerations: The preparation should account for the esthetic requirements, especially in anterior teeth or visible areas.
  • Material Selection: The choice of material (e.g., gold, porcelain, composite) will influence the preparation design and dimensions.

Radiographic Advancements in Caries Detection

Advancements in dental technology have significantly improved the detection and quantification of dental caries. This lecture will cover several key technologies used in caries detection, including Diagnodent, infrared and red fluorescence, DIFOTI, and QLF, as well as the film speeds used in radiographic imaging.

1. Diagnodent

  • Technology:

    • Utilizes infrared laser fluorescence for the detection and quantification of dental caries, particularly effective for occlusal and smooth surface caries.
    • Not as effective for detecting proximal caries.
  • Specifications:

    • Operates using red light with a wavelength of 655 nm.
    • Features a fiber optic cable with a handheld probe and a diode laser light source.
    • The device transmits light to the handheld probe and fiber optic tip.
  • Measurement:

    • Scores dental caries on a scale of 0-99.
    • Fluorescence is attributed to the presence of porphyrin, a compound produced by bacteria in carious lesions.
  • Scoring Criteria:

    • Score 1: <15 - No dental caries; up to half of enamel intact.
    • Score 2: 15-19 - Demineralization extends into the inner half of enamel or upper third of dentin.
    • Score 3: >19 - Extending into the inner portion of dentin.

2. Infrared and Red Fluorescence

  • Also Known As: Midwest Caries I.D. detection handpiece.
  • Technology:
    • Utilizes two wavelengths:
      • 880 nm - Infrared
      • 660 nm - Red
  • Application:
    • Designed for use over all tooth surfaces.
    • Particularly useful for detecting hidden occlusal caries.

3. DIFOTI (Digital Imaging Fiber Optic Transillumination)

  • Description:
    • An advancement of the Fiber Optic Transillumination (FOTI) technique.
  • Application:
    • Primarily used for the detection of proximal caries.
  • Drawback:
    • Difficulty in accurately determining the depth of the lesion.

4. QLF (Quantitative Laser Fluorescence)

  • Overview:
    • One of the most extensively investigated techniques for early detection of dental caries, introduced in 1978.
  • Effectiveness:
    • Good for detecting occlusal and smooth surface caries.
    • Challenging for detecting interproximal caries.

Film Speed in Radiographic Imaging

  • Film Types:
    • Film D: Best film for detecting incipient caries.
    • Film E: Most commonly used film in dentistry for caries detection.
    • Film F: Most recommended film speed for general use.
    • Film C: No longer available.

Pit and Fissure Sealants

Pit and fissure sealants are preventive dental materials applied to the occlusal surfaces of teeth to prevent caries in the pits and fissures. These sealants work by filling in the grooves and depressions on the tooth surface, thereby eliminating the sheltered environment where bacteria can thrive and cause decay.

Classification

Mitchell and Gordon (1990) classified pit and fissure sealants based on their composition and properties. While the specific classification details are not provided in the prompt, sealants can generally be categorized into:

  1. Resin-Based Sealants: These are the most common type, made from composite resins that provide good adhesion and durability.
  2. Glass Ionomer Sealants: These sealants release fluoride and bond chemically to the tooth structure, providing additional protection against caries.
  3. Polyacid-Modified Resin Sealants: These combine properties of both resin and glass ionomer sealants, offering improved adhesion and fluoride release.

Requisites of an Efficient Sealant

For a pit and fissure sealant to be effective, it should possess the following characteristics:

  • Viscosity: The sealant should be viscous enough to penetrate deep into pits and fissures.
  • Adequate Working Time: Sufficient time for application and manipulation before curing.
  • Low Sorption and Solubility: The material should have low water sorption and solubility to maintain its integrity in the oral environment.
  • Rapid Cure: Quick curing time to allow for efficient application and patient comfort.
  • Good Adhesion: Strong and prolonged adhesion to enamel to prevent microleakage.
  • Wear Resistance: The sealant should withstand the forces of mastication without wearing away.
  • Minimum Tissue Irritation: The material should be biocompatible and cause minimal irritation to oral tissues.
  • Cariostatic Action: Ideally, the sealant should have properties that inhibit the growth of caries-causing bacteria.

Indications for Use

Pit and fissure sealants are indicated in the following situations:

  • Newly Erupted Teeth: Particularly primary molars and permanent premolars and molars that have recently erupted (within the last 4 years).
  • Open or Sticky Pits and Fissures: Teeth with pits and fissures that are not well coalesced and may trap food particles.
  • Stained Pits and Fissures: Teeth with stained pits and fissures showing minimal decalcification.

Contraindications for Use

Pit and fissure sealants should not be used in the following situations:

  • No Previous Caries Experience: Teeth that have no history of caries and have well-coalesced pits and fissures.
  • Self-Cleansable Pits and Fissures: Wide pits and fissures that can be effectively cleaned by normal oral hygiene.
  • Caries-Free for Over 4 Years: Teeth that have been caries-free for more than 4 years.
  • Proximal Caries: Presence of caries on proximal surfaces, either clinically or radiographically.
  • Partially Erupted Teeth: Teeth that cannot be adequately isolated during the sealing process.

Key Points for Sealant Application

Age Range for Sealant Application

  • 3-4 Years of Age: Application is recommended for newly erupted primary molars.
  • 6-7 Years of Age: First permanent molars typically erupt during this age, making them prime candidates for sealant application.
  • 11-13 Years of Age: Second permanent molars and premolars should be considered for sealants as they erupt.

Concepts in Dental Cavity Preparation and Restoration

In operative dentistry, understanding the anatomy of tooth preparations and the techniques used for effective restorations is crucial. The importance of wall convergence in Class I amalgam restorations, the use of dental floss with retainers, and specific considerations for preparing mandibular first premolars.

1. Pulpal Wall and Axial Wall

Pulpal Wall

  • Definition: The pulpal wall is an external wall of a cavity preparation that is perpendicular to both the long axis of the tooth and the occlusal surface of the pulp. It serves as a boundary for the pulp chamber.
  • Function: This wall is critical in protecting the pulp from external irritants and ensuring the integrity of the tooth structure during restorative procedures.

Axial Wall

  • Transition: Once the pulp has been removed, the pulpal wall becomes the axial wall.
  • Definition: The axial wall is an internal wall that is parallel to the long axis of the tooth. It plays a significant role in the retention and stability of the restoration.

2. Wall Convergence in Class I Amalgam Restorations

Facial and Lingual Walls

  • Convergence: In Class I amalgam restorations, the facial and lingual walls should always be made slightly occlusally convergent.
  • Importance:
    • Retention: Slight convergence helps in retaining the amalgam restoration by providing a mechanical interlock.
    • Prevention of Dislodgement: This design minimizes the risk of dislodgement of the restoration during functional loading.

Clinical Implications

  • Preparation Technique: When preparing a Class I cavity, clinicians should ensure that the facial and lingual walls are slightly angled towards the occlusal surface, promoting effective retention of the amalgam.

3. Use of Dental Floss with Retainers

Retainer Safety

  • Bow of the Retainer: The bow of the retainer should be tied with approximately 12 inches of dental floss.
  • Purpose:
    • Retrieval: The floss allows for easy retrieval of the retainer or any broken parts if they are accidentally swallowed or aspirated by the patient.
    • Patient Safety: This precaution enhances patient safety during dental procedures, particularly when using matrix retainers for restorations.

Clinical Practice

  • Implementation: Dental professionals should routinely tie dental floss to retainers as a standard safety measure, ensuring that it is easily accessible in case of an emergency.

4. Pulpal Wall Considerations in Mandibular First Premolars

Anatomy of the Mandibular First Premolar

  • Pulpal Wall Orientation: The pulpal wall of the mandibular first premolar declines lingually. This anatomical feature is important to consider during cavity preparation.
  • Pulp Horn Location:
    • The facial pulp horn is prominent and located at a higher level than the lingual pulp horn. This asymmetry necessitates careful attention during preparation to avoid pulp exposure.

Bur Positioning

  • Tilting the Bur: When preparing the cavity, the bur should be tilted lingually to prevent exposure of the facial pulp horn.
  • Technique: This technique helps ensure that the preparation is adequately shaped while protecting the pulp from inadvertent injury.

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