Herpetic Gingivostomatitis

Herpetic gingivostomatitis is an infection of the oral cavity caused by the herpes simplex virus (HSV), primarily HSV type 1. It is characterized by inflammation of the gingiva and oral mucosa, and it is most commonly seen in children.

Etiology and Transmission

• Causative Agent: Herpes simplex virus (HSV).
• Transmission: The virus is communicated through personal contact, particularly via saliva. Common routes include:
  • Direct contact with an infected individual.
  • Transmission from mother to child, especially during the neonatal period.

Epidemiology

• Prevalence: Studies indicate that antibodies to HSV are present in 40-90% of individuals across different populations, suggesting widespread exposure to the virus.
• Age of Onset:
  • The incidence of primary herpes simplex infection increases after 6 months of age, peaking between 2 to 5 years.
  • Infants under 6 months are typically protected by maternal antibodies.

Clinical Presentation

• Incubation Period: 3 to 5 days following exposure to the virus.
• Symptoms:
  • General Symptoms: Fever, headache, malaise, and oral pain.
  • Oral Symptoms:
    • Initial presentation includes acute herpetic gingivostomatitis, with the gingiva appearing red, edematous, and inflamed.
    • After 1-2 days, small vesicles develop on the oral mucosa, which subsequently rupture, leading to painful ulcers with diameters of 1-3 mm.

Course of the Disease

• Self-Limiting Nature: The primary herpes simplex infection is usually self-limiting, with recovery typically occurring within 10 days.
• Complications: In severe cases, complications may arise, necessitating hospitalization or antiviral treatment.

Treatment

• Supportive Care:
  • Pain management with analgesics for fever and discomfort.
  • Ensuring adequate hydration through fluid intake.
  • Topical anesthetic ointments may be used to facilitate eating and reduce pain.
• Severe Cases:
  • Hospitalization may be required for severe symptoms or complications.
  • Antiviral agents (e.g., acyclovir) may be administered in severe cases or for immunocompromised patients.

Recurrence of Herpetic Infections

• Reactivation: Recurrent herpes simplex infections are due to the reactivation of HSV, which remains dormant in nerve tissue after the primary infection.
• Triggers for Reactivation:
  • Mucosal injuries (e.g., from dental treatment).
  • Environmental factors (e.g., sunlight exposure, citrus fruits).
• Location of Recurrence: Recurrent infections typically occur at the same site as the initial infection, commonly manifesting as herpes labialis (cold sores).

Self-Mutilation in Children: Causes and Management

Overview of Self-Mutilation

Self-mutilation through biting and other forms of self-injury can be a significant concern in children, particularly those with severe emotional disturbances or specific syndromes. Understanding the underlying causes and appropriate management strategies is essential for healthcare providers.

Associated Conditions

1. Lesch-Nyhan Syndrome (LNS):

   • A genetic disorder characterized by hyperuricemia, neurological impairment, and self-mutilating behaviors, including biting and head banging.
   • Children with LNS often exhibit severe emotional disturbances and may engage in self-injurious behaviors.

2. Congenital Insensitivity to Pain:

   • A rare condition where individuals cannot feel physical pain, leading to a higher risk of self-injury due to the inability to recognize harmful stimuli.
   • Children with this condition may bite or injure themselves without understanding the consequences.

3. Autism:

   • Children with autism may engage in self-injurious behaviors, including biting, as a response to sensory overload, frustration, or communication difficulties.
   • Friedlander and colleagues noted that facial bruising, abrasions, and intraoral traumatic ulcerations in autistic children are often the result of self-injurious behaviors rather than abuse.

Management Strategies

Management of self-mutilation in children requires careful consideration of the underlying condition and the child's developmental stage. Two primary approaches are often discussed:

1. Protective Appliances:

   • Mouthguards:
     • Littlewood and Mitchell reported that mouthguards can be beneficial for children with congenital insensitivity to pain. These devices help protect the oral cavity from self-inflicted injuries.
     • Mouthguards can serve as a temporary measure until the child matures enough to understand and avoid self-mutilating behaviors, which is typically learned through painful experiences.

2. Surgical Procedures:

   • In some cases, surgical intervention may be necessary to address severe self-injurious behaviors or to repair damage caused by biting.
   • The decision to pursue surgical options should be made on a case-by-case basis, considering the child's overall health, the severity of the behaviors, and the potential for improvement.

3. Pharmacological Interventions:

   • Carbamazepine:
     • Cusumano and colleagues reported that carbamazepine may be beneficial for children with Lesch-Nyhan syndrome. This medication can help manage behavioral symptoms and reduce self-injurious behaviors.

Cherubism

Cherubism is a rare genetic disorder characterized by bilateral or asymmetric enlargement of the jaws, primarily affecting children. It is classified as a benign fibro-osseous condition and is often associated with distinctive radiographic and histological features.

Clinical Presentation

• Jaw Enlargement:

  • Patients may present with symmetric or asymmetric enlargement of the mandible and/or maxilla, often noticeable at an early age.
  • The enlargement can lead to facial deformities and may affect the child's appearance and dental alignment.

• Tooth Eruption and Loss:

  • Teeth in the affected areas may exfoliate prematurely due to loss of support, root resorption, or interference with root development in permanent teeth.
  • Spontaneous loss of teeth can occur, or children may extract teeth themselves from the soft tissue.

Radiographic Features

• Bone Destruction:
  • Radiographs typically reveal numerous sharp, well-defined multilocular areas of bone destruction.
  • There is often thinning of the cortical plate surrounding the affected areas.
• Cystic Involvement:
  • The radiographic appearance is often described as "soap bubble" or "honeycomb" due to the multilocular nature of the lesions.

Case Report

• Example: McDonald and Shafer reported a case involving a 5-year-old girl with symmetric enlargement of both the mandible and maxilla.
  • Radiographic Findings: Multilocular cystic involvement was observed in both the mandible and maxilla.
  • Skeletal Survey: A complete skeletal survey did not reveal similar lesions in other bones, indicating the localized nature of cherubism.

Histological Features

• Microscopic Examination:
  • A biopsy of the affected bone typically shows a large number of multinucleated giant cells scattered throughout a cellular stroma.
  • The giant cells are large, irregularly shaped, and contain 30-40 nuclei, which is characteristic of cherubism.

Pathophysiology

• Genetic Basis: Cherubism is believed to have a genetic component, often inherited in an autosomal dominant pattern. Mutations in the SH3BP2 gene have been implicated in the condition.
• Bone Remodeling: The presence of giant cells suggests an active process of bone remodeling and resorption, contributing to the characteristic bone changes seen in cherubism.

Management

• Monitoring: Regular follow-up and monitoring of the condition are essential, especially during periods of growth.
• Surgical Intervention: In cases where the enlargement causes significant functional or aesthetic concerns, surgical intervention may be considered to remove the affected bone and restore normal contour.
• Dental Care: Management of dental issues, including premature tooth loss and alignment problems, is crucial for maintaining oral health.

Soldered Lingual Holding Arch as a Space Maintainer

Introduction

The soldered lingual holding arch is a classic bilateral mixed-dentition space maintainer used in the mandibular arch. It is designed to preserve the space for the permanent canines and premolars during the mixed dentition phase, particularly when primary molars are lost prematurely.

Design and Construction

• Components:

  • Bands: Fitted to the first permanent molars.
  • Wire: A 0.036- or 0.040-inch stainless steel wire is contoured to the arch.
  • Extension: The wire extends forward to make contact with the cingulum area of the incisors.

• Arch Form: The wire is contoured to provide an anterior arch form, allowing for the alignment of the incisors while ensuring it does not interfere with the normal eruption paths of the teeth.

Functionality

• Stabilization: The design stabilizes the positions of the lower molars, preventing them from moving mesially and maintaining the incisor relationship to avoid retroclination.
• Leeway Space: The arch helps sustain the canine-premolar segment space, utilizing the leeway space available during the mixed dentition phase.

Clinical Considerations

• Eruption Path: The lingual wire must be contoured to avoid interference with the normal eruption paths of the permanent canines and premolars.
• Breakage and Hygiene: The soldered lingual holding arch is designed to present minimal problems with breakage and minimal oral hygiene concerns.
• Eruptive Movements: It should not interfere with the eruptive movements of the permanent teeth, allowing for natural development.

Timing of Placement

• Transitional Dentition Period: The bilateral design and use of permanent teeth as abutments allow for application during the full transitional dentition period of the buccal segments.
• Timing of Insertion: Lower lingual arches should not be placed before the eruption of the permanent incisors due to their frequent lingual eruption path. If placed too early, the lingual wire may interfere with normal incisor positioning, particularly before the lateral incisor erupts.
• Anchorage: Using primary incisors as anterior stops does not provide sufficient anchorage to prevent significant loss of arch length.

1. Behavior Modification: Aversive Conditioning (HOME)

• Definition: Aversive conditioning is a behavior modification technique used to manage undesirable behaviors in children, particularly in a dental setting.
• Method: Known as the Hand-Over-Mouth Exercise (HOME), this technique was introduced by Evangeline Jordan in 1920.
  • Procedure: The dentist gently places their hand over the child’s mouth to prevent them from speaking or crying, allowing for a calm environment to perform dental procedures. This method is intended to help the child understand that certain behaviors (e.g., crying or moving excessively) are not conducive to receiving care.

2. Dental Materials: Crowns

• Cheng Crowns:

  • Composition: These crowns feature a pure resin facing, which makes them stain-resistant.
  • Design: Pre-crimped for ease of placement and adaptation to the tooth structure.

• Pedo Pearls:

  • Description: Aluminum crown forms coated with tooth-colored epoxy paint.
  • Durability: Relatively soft, which may affect their long-term durability compared to other crown materials.

3. Oral Hygiene for Infants

• Gum Pad Cleaning:
  • Timing: Cleaning of gum pads can begin as early as the first week after birth.
  • Parental Responsibility: Parents should brush or clean their baby’s gums and emerging teeth daily until the child is old enough to manage oral hygiene independently.

4. Indicators of Trauma and Abuse in Children

• Frenum Conditions:

  • Maxillary Labial Frenum: A torn frenum in a young child may indicate trauma from a slap, fist blow, or forced feeding.
  • Lingual Frenum: A torn lingual frenum could suggest sexual abuse or forced feeding.

• Signs of Abuse:

  • Bruising or Petechiae: Presence of bruising or petechiae on the soft and hard palate may indicate sexual abuse, particularly in cases of oral penetration.
  • Infection or Ulceration: If any signs of infection or ulceration are noted, specimens should be cultured for sexually transmitted diseases (STDs) such as gonorrhea, syphilis, or venereal warts.

• Neglect Indicators:

  • A child presenting with extensive untreated dental issues, untreated infections, or dental pain may be considered a victim of physical neglect, indicating that parents are not attending to the child’s basic medical needs.

5. Classical Conditioning

• Pavlov’s Contribution: Ivan Petrovich Pavlov was the first to study classical conditioning, a learning process that occurs through associations between an environmental stimulus and a naturally occurring stimulus.
  • Relevance in Dentistry: Understanding classical conditioning can help dental professionals develop strategies to create positive associations with dental visits, thereby reducing anxiety and fear in children.

Frenectomy and Frenotomy

A frenectomy is a surgical procedure that involves the complete excision of the frenum and its periosteal attachment. This procedure is typically indicated when large, fleshy frenums are present and may interfere with oral health or function.

Indications for Frenectomy

The decision to perform a frenectomy or frenotomy should be based on the ability to maintain gingival health and the presence of specific clinical conditions. The following are key indications for treating a high frenum:

1. Persistent Gingival Inflammation:

   • A high frenum attachment associated with an area of persistent gingival inflammation that has not responded to root planing and good oral hygiene practices.

2. Progressive Recession:

   • A frenum associated with an area of gingival recession that is progressive, indicating that the frenum may be contributing to the loss of attached gingiva.

3. Midline Diastema:

   • A high maxillary frenum that is associated with a midline diastema (gap between the central incisors) that persists after the complete eruption of the permanent canines.

4. Mandibular Lingual Frenum:

   • A mandibular lingual frenum that inhibits the tongue from making contact with the maxillary central incisors, potentially interfering with the child’s ability to articulate sounds such as /t/, /d/, and /l/.
   • If the child has sufficient range of motion to raise the tongue to the roof of the mouth, surgery may not be indicated. Most children typically develop the ability to produce these sounds after the age of 6 or 7, and speech therapy may be recommended if issues persist.

Surgical Considerations

• Keratinized Gingiva:

  • If a high frenum is associated with an area of no or minimal keratinized gingiva, a vestibular extension or graft may be used to augment the surgical procedure. This is important for ensuring stable long-term results.

• Frenotomy vs. Frenectomy:

  • In cases where a frenotomy or frenectomy does not create stable long-term results, alternative approaches may be considered. Bohannan indicated that if there is an adequate band of attached gingiva, high frenums and vestibular depth do not pose significant problems.

• Standard Approach:

  • The use of surgical procedures to eliminate the frenum pull is considered a standard approach when indicated. The goal is to improve gingival health and function while minimizing the risk of recurrence.