Agents Used for Sedation in Children

1. Nitrous Oxide (N₂O)

   • Type: Gaseous agent
   • Description: Commonly used for conscious sedation in pediatric dentistry. It provides anxiolytic and analgesic effects, making dental procedures more tolerable for children.

2. Benzodiazepines

   • Examples:
     • Diazepam: Used for its anxiolytic and sedative properties.
     • Midazolam: Frequently utilized for its rapid onset and short duration of action.

3. Barbiturates

   • Description: Sedative-hypnotics that can be used for sedation, though less commonly in modern practice due to the availability of safer alternatives.

4. Chloral Hydrate

   • Description: A sedative-hypnotic agent used for its calming effects in children.

5. Narcotics

   • Examples:
     • Meperidine: Provides analgesia and sedation.
     • Fentanyl: A potent opioid used for sedation and pain management.

6. Antihistamines

   • Examples:
     • Hydroxyzine: An anxiolytic and sedative.
     • Promethazine (Phenergan): Used for sedation and antiemetic effects.
     • Chlorpromazine: An antipsychotic that can also provide sedation.
     • Diphenhydramine: An antihistamine with sedative properties.

7. Dissociative Agents

   • Example:
     • Ketamine: Provides dissociative anesthesia, analgesia, and sedation. It is particularly useful in emergency settings and for procedures that may cause significant discomfort.

Phenytoin-Induced Gingival Overgrowth

• Phenytoin (Dilantin):
  • An anticonvulsant medication primarily used in the treatment of epilepsy.
  • First introduced in 1938 by Merrit and Putnam.

Gingival Hyperplasia

• Gingival hyperplasia refers to the overgrowth of gum tissue, which can lead to aesthetic concerns and functional issues, such as difficulty in maintaining oral hygiene.
• Historical Context:
  • The association between phenytoin therapy and gingival hyperplasia was first reported by Kimball in 1939.
  • In his study, 57% of 119 patients taking phenytoin for seizure control experienced some degree of gingival overgrowth.

Mechanism of Gingival Overgrowth

• Fibroblast Activity:

  • Early research indicated an increase in the number of fibroblasts in the gingival tissues of patients receiving phenytoin.
  • This led to the initial terminology of "Dilantin hyperplasia."

• Current Understanding:

  • Subsequent studies, including those by Hassell and colleagues, have shown that true hyperplasia does not exist in this condition.
  • Findings indicate:
    • There is no excessive collagen accumulation per unit of tissue.
    • Fibroblasts do not appear abnormal in number or size.
  • As a result, the term phenytoin-induced gingival overgrowth is now preferred, as it more accurately reflects the condition.

Clinical Implications

• Management:

  • Patients on phenytoin should be monitored for signs of gingival overgrowth, especially if they have poor oral hygiene or other risk factors.
  • Dental professionals should educate patients about maintaining good oral hygiene practices to minimize the risk of gingival overgrowth.
  • In cases of significant overgrowth, treatment options may include:
    • Improved oral hygiene measures.
    • Professional dental cleanings.
    • Surgical intervention (gingivectomy) if necessary.

• Patient Education:

  • It is important to inform patients about the potential side effects of phenytoin, including gingival overgrowth, and the importance of regular dental check-ups.

Polycarbonate Crowns in Pedodontics

Polycarbonate crowns are commonly used in pediatric dentistry, particularly for managing anterior teeth affected by nursing bottle caries. These crowns serve as temporary fixed prostheses for primary teeth, providing a functional and aesthetic solution until the natural teeth exfoliate. This lecture will discuss the indications, contraindications, and advantages of polycarbonate crowns in pedodontic practice.

Nursing Bottle Caries

• Definition: Nursing bottle caries, also known as early childhood caries, is a condition characterized by the rapid demineralization of the anterior teeth, primarily affecting the labial surfaces.
• Progression: The lesions begin on the labial face of the anterior teeth and can lead to extensive demineralization, affecting the entire surface of the teeth.
• Management Goal: The primary objective is to stabilize the lesions without attempting a complete reconstruction of the coronal anatomy.

Treatment Approach

1. Preparation of the Lesion:

   • The first step involves creating a clean periphery around the carious lesion using a small round bur.
   • Care should be taken to leave the central portion of the affected dentin intact to avoid pulp exposure.
   • This preparation allows for effective ion exchange with glass ionomer materials, facilitating a good seal.

2. Use of Polycarbonate Crowns:

   • Polycarbonate crowns are indicated as temporary crowns for deciduous anterior teeth that will eventually exfoliate.
   • They provide a protective covering for the tooth while maintaining aesthetics and function.

Contraindications for Polycarbonate Crowns

Polycarbonate crowns may not be suitable in certain situations, including:

• Severe Bruxism: Excessive grinding can lead to premature failure of the crown.
• Deep Bite: A deep bite may cause undue stress on the crown, leading to potential fracture or dislodgment.
• Excessive Abrasion: High levels of wear can compromise the integrity of the crown.

Advantages of Polycarbonate Crowns

Polycarbonate crowns offer several benefits in pediatric dentistry:

• Time-Saving: The application of polycarbonate crowns is relatively quick, making them efficient for both the clinician and the patient.
• Ease of Trimming: These crowns can be easily trimmed to achieve the desired fit and contour.
• Adjustability: They can be adjusted with pliers, allowing for modifications to ensure proper seating and comfort for the patient.

Frenectomy and Frenotomy

A frenectomy is a surgical procedure that involves the complete excision of the frenum and its periosteal attachment. This procedure is typically indicated when large, fleshy frenums are present and may interfere with oral health or function.

Indications for Frenectomy

The decision to perform a frenectomy or frenotomy should be based on the ability to maintain gingival health and the presence of specific clinical conditions. The following are key indications for treating a high frenum:

1. Persistent Gingival Inflammation:

   • A high frenum attachment associated with an area of persistent gingival inflammation that has not responded to root planing and good oral hygiene practices.

2. Progressive Recession:

   • A frenum associated with an area of gingival recession that is progressive, indicating that the frenum may be contributing to the loss of attached gingiva.

3. Midline Diastema:

   • A high maxillary frenum that is associated with a midline diastema (gap between the central incisors) that persists after the complete eruption of the permanent canines.

4. Mandibular Lingual Frenum:

   • A mandibular lingual frenum that inhibits the tongue from making contact with the maxillary central incisors, potentially interfering with the child’s ability to articulate sounds such as /t/, /d/, and /l/.
   • If the child has sufficient range of motion to raise the tongue to the roof of the mouth, surgery may not be indicated. Most children typically develop the ability to produce these sounds after the age of 6 or 7, and speech therapy may be recommended if issues persist.

Surgical Considerations

• Keratinized Gingiva:

  • If a high frenum is associated with an area of no or minimal keratinized gingiva, a vestibular extension or graft may be used to augment the surgical procedure. This is important for ensuring stable long-term results.

• Frenotomy vs. Frenectomy:

  • In cases where a frenotomy or frenectomy does not create stable long-term results, alternative approaches may be considered. Bohannan indicated that if there is an adequate band of attached gingiva, high frenums and vestibular depth do not pose significant problems.

• Standard Approach:

  • The use of surgical procedures to eliminate the frenum pull is considered a standard approach when indicated. The goal is to improve gingival health and function while minimizing the risk of recurrence.

Self-Mutilation in Children: Causes and Management

Overview of Self-Mutilation

Self-mutilation through biting and other forms of self-injury can be a significant concern in children, particularly those with severe emotional disturbances or specific syndromes. Understanding the underlying causes and appropriate management strategies is essential for healthcare providers.

Associated Conditions

1. Lesch-Nyhan Syndrome (LNS):

   • A genetic disorder characterized by hyperuricemia, neurological impairment, and self-mutilating behaviors, including biting and head banging.
   • Children with LNS often exhibit severe emotional disturbances and may engage in self-injurious behaviors.

2. Congenital Insensitivity to Pain:

   • A rare condition where individuals cannot feel physical pain, leading to a higher risk of self-injury due to the inability to recognize harmful stimuli.
   • Children with this condition may bite or injure themselves without understanding the consequences.

3. Autism:

   • Children with autism may engage in self-injurious behaviors, including biting, as a response to sensory overload, frustration, or communication difficulties.
   • Friedlander and colleagues noted that facial bruising, abrasions, and intraoral traumatic ulcerations in autistic children are often the result of self-injurious behaviors rather than abuse.

Management Strategies

Management of self-mutilation in children requires careful consideration of the underlying condition and the child's developmental stage. Two primary approaches are often discussed:

1. Protective Appliances:

   • Mouthguards:
     • Littlewood and Mitchell reported that mouthguards can be beneficial for children with congenital insensitivity to pain. These devices help protect the oral cavity from self-inflicted injuries.
     • Mouthguards can serve as a temporary measure until the child matures enough to understand and avoid self-mutilating behaviors, which is typically learned through painful experiences.

2. Surgical Procedures:

   • In some cases, surgical intervention may be necessary to address severe self-injurious behaviors or to repair damage caused by biting.
   • The decision to pursue surgical options should be made on a case-by-case basis, considering the child's overall health, the severity of the behaviors, and the potential for improvement.

3. Pharmacological Interventions:

   • Carbamazepine:
     • Cusumano and colleagues reported that carbamazepine may be beneficial for children with Lesch-Nyhan syndrome. This medication can help manage behavioral symptoms and reduce self-injurious behaviors.

Maternal Attitudes and Corresponding Child Behaviors

1. Overprotective:

   • Mother's Behavior: A mother who is overly protective tends to shield her child from potential harm or discomfort, often to the point of being controlling.
   • Child's Behavior: Children raised in an overprotective environment may become shy, submissive, and anxious. They may struggle with independence and exhibit fearfulness in new situations due to a lack of opportunities to explore and take risks.

2. Overindulgent:

   • Mother's Behavior: An overindulgent mother tends to give in to the child's demands and desires, often providing excessive affection and material rewards.
   • Child's Behavior: This can lead to children who are aggressive, demanding, and prone to temper tantrums. They may struggle with boundaries and have difficulty managing frustration when they do not get their way.

3. Under-affectionate:

   • Mother's Behavior: A mother who is under-affectionate may be emotionally distant or neglectful, providing little warmth or support.
   • Child's Behavior: Children in this environment may be generally well-behaved but can struggle with cooperation. They may be shy and cry easily, reflecting their emotional needs that are not being met.

4. Rejecting:

   • Mother's Behavior: A rejecting mother may be dismissive or critical of her child, failing to provide the emotional support and validation that children need.
   • Child's Behavior: This can result in children who are aggressive, overactive, and disobedient. They may act out as a way to seek attention or express their frustration with the lack of nurturing.

5. Authoritarian:

   • Mother's Behavior: An authoritarian mother enforces strict rules and expectations, often without providing warmth or emotional support. Discipline is typically harsh and non-negotiable.
   • Child's Behavior: Children raised in authoritarian environments may become evasive and dawdling, as they may fear making mistakes or facing punishment. They may also struggle with self-esteem and assertiveness.