What is the primary mechanism of action of Shiga-like toxins produced by EHEC?
1) Inhibits protein synthesis by binding to ribosomes
2) Induces lipid peroxidation in cell membranes
3) Increases intracellular cAMP
4) Induces endothelial cell damage
📝 Explanation:
Shiga-like toxins produced by EHEC bind to ribosomes in target cells, particularly endothelial cells, and inhibit protein synthesis. This leads to cell damage and contributes to the development of hemolytic uremic syndrome.