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General Medicine - 3 Questions
CPR should have a ratio of chest compression to mouth breathing of 4:1
What is the primary function of the ATP7B protein in the context of Wilson's disease? 1) Copper uptake in the gut 2) Copper incorporation into ceruloplasmin 3) Copper excretion from hepatocytes 4) Copper metabolism in erythrocytes
The ATP7B protein is essential for copper excretion from hepatocytes into bile, and its deficiency leads to copper accumulation in the liver and other tissues in Wilson's disease.
Which autoantibody is most specific for the diagnosis of SLE?1) Anti-double stranded DNA2) Anti-Smith antigen3) Anti-nuclear antibody4) Anti-RNP antibody
Anti-Smith (anti-Sm) antibodies are highly specific for SLE and are found in about 20-30% of patients. While antinuclear antibodies and anti-double stranded DNA antibodies are also associated with SLE, they are less specific as they can also be present in other conditions.