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Anatomy - 3 Questions
The auriculotemporal nerve carries some fibers which are sensory to lining of tympanic cavity
Clavicle is the first bone to Ossify in the body
The largest resting membrane potential is observed in skeletal muscle. Resting membrane potential (RMP) is the electrical potential difference across the membrane of a cell when it is not undergoing an action potential or a similar excitation. It is crucial for the functioning of excitable cells, such as neurons and muscle cells, as it is the basis for the transmission of electrical signals. The RMP is primarily determined by the concentration gradients of ions across the cell membrane and the permeability of the membrane to those ions. In skeletal muscle cells, the resting membrane potential is typically around -90 millivolts (mV). This relatively high negative value is due to the higher concentration of potassium ions (K+) inside the cell compared to the outside, and the lower concentration of sodium ions (Na+) inside the cell compared to the outside. The cell membrane is more permeable to K+ than to Na+ at rest, which allows K+ to leak out through potassium channels and sets up the resting membrane potential. Smooth muscle cells, on the other hand, have a resting membrane potential that is generally less negative than that of skeletal muscle cells. The typical RMP in smooth muscle cells ranges from -40 to -70 mV, which is closer to the threshold for depolarization and makes these cells more responsive to stimuli that could cause contraction. The difference in RMP between smooth and skeletal muscle is due to variations in ion channel expression and the activity of ion pumps, which control the ionic composition of the intracellular and extracellular environments. To summarize: 1. Skeletal muscle cells have a resting membrane potential of approximately -90 mV. 2. Smooth muscle cells have a resting membrane potential that is generally more positive than skeletal muscle cells, typically ranging from -40 to -70 mV.