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General Pathology - 3 Questions
Osmotic fragility is increased in hereditary spherocytosis due to the abnormal shape and membrane stability of red blood cells.
Splenomegaly is not usually seen in sickle cell anemia; instead, autosplenectomy often occurs due to repeated splenic infarctions.
In sickle cell trait, the number of bands found in hemoglobin is typically 2, representing both HbA and HbS.