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Pharmacology - 3 Questions
Which of the following agents is used for the treatment of Thrombocytopenia secondary to myelosuppressive cancer chemotherapy?
1) Filgrastim 2) Sargramostim 3) Oprelvekin 4) Erythropoietin
Oprelvekin (Interleukin 11) is the only agent approved by the FDA for treatment of thrombocytopenia secondary to myelosuppressive cancer chemotherapy Filgrastim (G-CSF) and Sargramostim (GM-SCF) are used in the treatment of neutropenia Erythropoietin is used in treatment of anemia
Nonselective beta blocker possessing quinidine-like membrane stabilizing effects.
1) pindolol 2) acebutolol 3) sotalol 4) esmolol
Beta-blockers, such as propranolol, labetalol, and pindolol, can have membrane stabilizing effects (eg, quinidinelike effects, Vaughan-Williams class I antiarrhythmic effects). This property, usually not evident with therapeutic doses, may significantly contribute to toxicity by prolonging QRS duration and impairing cardiac conduction. Seizures are more commonly observed in the drugs with quinidinelike membrane stabilizing effects.
Which of the following action is ascribed to delta type of opioid receptors?
1) Supraspinal analgesis 2) Respiratory depression 3) Euphoria 4) Reduced intestinal motility
Functions of delta type opioid receptors are:
supraspinal analgesia spinal analgesia modulation of hormone and neurotransmitter release
MCQ