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NEET MDS Quiz - Practice Test
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Practice Test

Pharmacology - 3 Questions

1
Pharmacology

Which of the following agents is used for the treatment of Thrombocytopenia secondary to myelosuppressive cancer chemotherapy?

1) Filgrastim
2) Sargramostim
3) Oprelvekin
4) Erythropoietin

📝 Explanation:

Oprelvekin (Interleukin 11) is the only agent approved by the FDA for treatment of thrombocytopenia secondary to myelosuppressive cancer chemotherapy
Filgrastim (G-CSF) and Sargramostim (GM-SCF) are used in the treatment of neutropenia
Erythropoietin is used in treatment of anemia

2
Pharmacology

False statement regarding phenytoin is?

1) It is a teratogenic drug
2) Highly protein bound
3) Induces insulin secretion 
4) Follows saturation kinetics 

📝 Explanation:

Phenytoin inhibits insulin secretion and causes hyperglycemia.

3
Pharmacology

Which of the following fluoroquinolones does not require dose adjustment in a patient with creatinine clearance of < 50mg/min?

1) Ciprofloxacin 
2) Trovafloxacin 
3) Lomefloxacin 
4) Sparfloxacin

📝 Explanation:

Fluoroquinolones that are excreted mainly by non renal mechanisms:

Pefloxacin Trovafloxacin Grepofloxacin Nalidixic acid

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