A medication that reduces the rate of aqueous humor formation in acute glaucoma
1) phenothiazines
2) amphotericin B
3) Isoniazid
4) carbonic anhydrase inhibitors
๐ Explanation:
Carbonic anhydrase is found in erythrocytes, kidney, gut, ciliary body, choroid plexus, and glial cells.
Carbonic anhydrase inhibitors are used primarily as probes for studying renal transport mechanisms and in the treatment of glaucoma
When used to treat glaucoma, carbonic anhydrase inhibitors diminish the transport of HCO3 - and Na+ by the ciliary process, which limits intraocular pressure.
This reduces the formation of aqueous humor by up to 50%, thereby reducing the intraocular pressure. These agents can also limit CSF and endolymph formation.
MCQ